A fluidic valve for switching between different fluid coupling states includes a stator having at least one fluidic stator interface, a rotor having at least one fluidic rotor interface, wherein the rotor is rotatable relative to the stator to thereby switch the fluidic valve between a plurality of different fluid coupling states between the at least one fluidic stator interface and the at least one fluidic rotor interface, and a force transmission mechanism configured for pressing the stator and the rotor together by a contactless force transmission to provide for a fluid tight sealing between the stator and the rotor.

The present invention relates to a method for providing information from a fraction collector in a liquid chromatography system, the system comprising a column, at least one reservoir for containing a fluid, at least one pump connected to said reservoir, a column arranged to receive an input from the reservoir, a measuring device for performing measurements on a fluid output from the column, and a fraction collector for receiving said fluid output in a plurality of receiving vessels, wherein the method comprisesdetermining at least one parameter of the fraction collector, andproviding information of said parameter on a display in the form of a graphical representation.

An apparatus, process, and system are disclosed that effectively provide separation of a combined gas/liquid flow stream into its separated gas and liquid factions. The invention is primarily directed to the fields of preparative supercritical fluid chromatography (SFC) and supercritical fluid extraction (SFE), but will have other utilization and applicability where phases of dramatically different density, viscosity and volumetric flow require separation.

Provided is a gas-spouting liquid-sample injector, for supplying a mist of liquid sample into a container, including: a sample introduction tube having an outer tube for a nebulizer gas and an inner tube for a liquid, the inner tube having a projecting section protruding from the lower end of the outer tube; a branch tube provided in the container, having a main line allowing an insertion of the sample introduction tube and a bypass line branched from the main line; an inlet portion provided at the upper end of the main line, for making gas-tight contact with the lower end of the outer tube; an outlet portion provided at the lower end of the main line, for making gas-tight contact with the outer circumferential surface of the inner tube; and a blower tube extending from the lower end of the bypass line toward an area below the outlet portion.

A mixer-settler countercurrent chromatography centrifuge and rotor of increased capacity is described.

A elution product yield improvement system includes a processor, an estimation model and an elution controller application including instructions configured, when executed by the processors, to receive initialization data; instantiate a communication link to a remote process/automation system; determine collection criteria; initiate collection; read data values; computing an area ratio via the estimation model; and cease collection. A computer-implemented method for improving elution yield and purity includes receiving initialization data; instantiating a communication link to a remote process/automation system; determining collection criteria; initiating collection; reading data values; computing an area ratio; and ceasing collection. A non-transitory computer readable medium includes program instructions that when executed, cause a computer to receive initialization data; instantiate a communication link to a remote process/automation system; determine collection criteria; initiate collection; read data values; computing an area ratio via the estimation model; and cease collection.

A target component is collected using a preparative separation and purification device having a holder for holding a trap column in which the target component has been captured, a liquid feeder for feeding a first solvent having compatibility with the water remaining in the trap column and a second solvent having low compatibility with water and high compatibility with the first solvent into the trap column, a flow-path switch for connecting the exit end of the trap column to a waste liquid flow path and a collection flow path, and a control unit for controlling the flow-path switch so that solution including water flows into the waste liquid flow path.

A plasma etching apparatus includes first, second and third chambers, and a plasma generation device. An inner cross-sectional area and shape of the second chamber interior substantially corresponds to the upper surface of a substrate, and a substrate support is disposed so that, in use, the substrate is substantially in register with the interior of the second chamber, and the upper surface of the substrate is positioned at a distance of 80 mm or less from the interface between the second and third chambers.

A liquid sending pump supplies an eluent. A first sample supplier supplies a sample to a first separation column used for an analysis of the sample. A second sample supplier supplies a sample to a second separation column used for separation of the sample. A detector detects a sample that has passed through the first separation column or the second separation column. A flow-path switching valve is switchable between a first flow-path state in which an eluent that has been supplied by the liquid sending pump to the first separation column and a sample that has passed through the first separation column to the detector and a second flow-path state in which an eluent that has been supplied by the liquid sending pump and part of a sample that has passed through the second separation column to the detector.

The present invention relates to a method for performing liquid chromatography purification of one or more target molecules from a sample comprising: providing an eluent flow having one or more target molecules, measuring an output parameter indicative of the content of the one or more target molecules in the eluent flow, storing output parameter data, and dividing the eluent flow into consecutive eluent fractions, dividing the output parameter data into corresponding data fractions, in each data fraction obtaining a value indicative of characteristic behavior of the measured output parameter, identifying trends in the measured output parameter based upon the obtained value in consecutive data fractions, and identifying peak(s) in the measured output parameter correlated to eluent fractions based upon the identified trends, whereby information of identified peak(s) and correlated eluent fraction(s) can be presented and purified sample(s) from the eluent may be collected.