A vesicle in a liquid composition including an amphiphilic diblock copolymer of the PMOXA.sub.a-b-PDMS.sub.c-d type as vesicle membrane forming material, further including as an additive from about 0.05% to about 1% v/v of reactive end group functionalised PDMS.sub.e-f, and a transmembrane protein. The vesicle optionally includes about 1 to about 12% v/v of triblock copolymer of the PMOXA.sub.a-b-PDMS.sub.c-d-PMOXA.sub.a-b type as membrane forming material.

The device, that can be implanted in the intestinal cavity, comprises a reactor comprising a semi-permeable or porous membrane or coating linked to a element for attachment to an intestinal or gastric wall. The reactor can be in the form of a ribbon, a structure having more than two faces or an open structure delimiting a lumen, comprising, or formed from, a semi-permeable or porous membrane. The reactor can also delimit, at least partially with the semi-permeable or porous membrane of same, a closed inner space. The reactor can comprise or carry enzymes or micro-organisms, in particular bacteria or yeast. The reactor is used for generating a chemical reaction with one or more molecules present in the intestine, or for producing one or more biologically active molecules. It can, in particular, be used for consuming sugars, disaccharides and simple sugars or producing essential amino acids or other molecules having a positive effect on the health.

Disclosed herein are compositions and methods that involve inserting connector protein channels of bacteriophage DNA packaging motors into copolymeric membranes via liposome-polymer fusion, which can be used as nanopore sensors for biomedical applications such as high throughput protein sequencing or cancer diagnosis. For example, disclosed are compositions comprising a copolymeric membrane into which a connector protein channel of a bacteriophage packaging motor has been inserted.

Disclosed are a method for whole blood filtration and a filter membrane structure for whole blood filtration, specifically including the following steps: (1) a filter membrane structure made up of at least two filtration membranes sequentially stacked from top to bottom is selected, and subjected to hemagglutinin treatment for later use; (2) a whole blood sample is added to the filter membrane structure for filtration; and (3) the filtered serum or plasma is collected. The filter membrane structure is composed of at least two filtration membranes stacked from top to bottom, and the pore sizes of the filtration membranes stacked gradually decrease from top to bottom, and the areas of the same gradually increase or are equal to each other from top to bottom.

A photothermal distillation membrane comprising a tridecafluoro-1,1,2,2-tetrahydrooctyl-trichlorosilane (FTCS) fluoro-silanized, polydopamine (PDA) coated, polyvinylidene fluoride (PVDF) membrane is disclosed, as well as a process for synthesizing a FTCS-PDA-PVDF membrane. A tridecafluoro-1,1,2,2-tetrahydrooctyl-trichlorosilane (FTCS) fluoro-silanized, polydopamine (PDA) containing bacterial nanocellulose (BNC) aerogel membrane is also disclosed, as well as a process for synthesizing a FTCS-PDA/BNC aerogel membrane.

The disclosure relates to processes, related polyacid polymers, and related articles for functionalizing a porous membrane by contacting the membrane with a polyacid polymer at low pH to stably adsorb a polyacid layer on the membrane pore surface, in particular polyacid polymers including repeating units with a pendent metal-binding ligand or star polyacid polymers. The resulting functionalized membrane is characterized by a high density of free acid groups, resulting in a higher specific capacity for its intended application. The process allows functionalization of porous membranes in a very simple, one-step process, for example without a need to derivatize an adsorbed polyacid layer to impart metal-binding ligand functionality thereto. Such functional membranes may find multiple uses, including rapid, selective binding of proteins for their purification or immobilization.

The present invention relates to a device and method for sample preparation and collection. More closely the invention relates to a device to isolate DNA, RNA and proteins or other biomolecules in one single step from the same undivided sample

A microchannel-membrane device comprises a microchannel extending through at least one electrode, the microchannel having a predetermined depth; an ionic permselective medium, such as a membrane, across the microchannel between the electrodes; and a heater, or array of heaters, embedded below the microchannel on at least one side of the permselective membrane. The heaters can be either prefabricated or dynamically patterned using laser illumination with/without photoconductive coating. The heaters are on the depletion side of the membrane and induce a vortex which limits the growth of the diffusion area. Operation of the heaters allows for controlled positioning of the end of the diffusion area and with it also the position of the preconcentrated molecule plug.

Provided are methods of preparing, detecting, and/or assaying an analyte of interest from a sample. The methods utilize functionalized silicon membranes, such as, for example, functionalized silicon nanomembranes. Samples that can be used in the methods may be biological samples, food samples, environmental samples, industrial samples, or a combination thereof. Also provided are kits to perform methods of the present disclosure.

Disclosed is a urea biosensor that is stable at ambient temperature, and methods of making thereof.