Embodiments disclosed herein are directed to membranes for filtration, methods of manufacturing the same, and membrane modules incorporating the same. In an embodiment, a membrane is disclosed. The membrane includes a porous cellulose layer, a polyamide thin film layer bonded to the porous cellulose layer, and a fabric support layer that supports the porous cellulose layer and the polyamide thin film layer. The porous cellulose layer has a pore size of about 30 nm to about 500 nm at an exposed surface of the porous cellulose layer.

Embodiments disclosed herein are directed to membranes for filtration, methods of manufacturing the same, and membrane modules incorporating the same. In an embodiment, a membrane is disclosed. The membrane includes a porous cellulose layer, a polyamide thin film layer bonded to the porous cellulose layer, and a fabric support layer that supports the porous cellulose layer and the polyamide thin film layer. The porous cellulose layer has a pore size of about 30 nm to about 500 nm at an exposed surface of the porous cellulose layer.

Provided is a flow path material for a liquid separation apparatus, which is less likely to collapse upon the application of a high pressure to the flow path material and causes a lower reduction of the flow rate. The flow path material for a liquid separation apparatus includes a tricot fabric containing thermoplastic core-sheath composite fibers each made of two kinds of polyester resins having different melting points or softening points. The flow path material for a liquid separation apparatus is configured such that: in the thermoplastic core-sheath composite fibers, a high-melting-point component is placed in the core, while a low-melting-point component is placed in the sheath; the tricot fabric is a tricot knitted fabric knitted with a two-guide-reed knitting machine using the thermoplastic core-sheath composite fibers as a front yarn and a back yarn and is rigidified by the thermoplastic core-sheath composite fibers being bonded to each other; the tricot fabric has a wale density of 45 to 70 yarns/inch (2.54 cm) and a course density of 40 to 70 yarns/inch (2.54 cm); and, when the tricot fabric is heat-pressed at 90? C. and 4.0 MPa for 3 minutes, the percentage of change in the thickness of the tricot fabric before and after pressing is 10% or less.

Provided is a flow path material for a liquid separation apparatus, which is less likely to collapse upon the application of a high pressure to the flow path material and causes a lower reduction of the flow rate. The flow path material for a liquid separation apparatus includes a tricot fabric containing thermoplastic core-sheath composite fibers each made of two kinds of polyester resins having different melting points or softening points. The flow path material for a liquid separation apparatus is configured such that: in the thermoplastic core-sheath composite fibers, a high-melting-point component is placed in the core, while a low-melting-point component is placed in the sheath; the tricot fabric is a tricot knitted fabric knitted with a two-guide-reed knitting machine using the thermoplastic core-sheath composite fibers as a front yarn and a back yarn and is rigidified by the thermoplastic core-sheath composite fibers being bonded to each other; the tricot fabric has a wale density of 45 to 70 yarns/inch (2.54 cm) and a course density of 40 to 70 yarns/inch (2.54 cm); and, when the tricot fabric is heat-pressed at 90? C. and 4.0 MPa for 3 minutes, the percentage of change in the thickness of the tricot fabric before and after pressing is 10% or less.

Problems that the invention is to solve is to provide a composite hollow fiber membrane being excellent in separation performance and permeation performance, having high membrane strength, and capable of being easily produced, and a method for producing the same. The present invention relates to a composite hollow fiber membrane including at least a layer (A) and a layer (B), in which the composite hollow fiber membrane has an outer diameter of 20 to 350 ?m and an inner diameter of 14 to 250 ?m, the tensile modulus of the composite hollow fiber membrane is from 1,000 to 6,500 MPa, the layer (A) contains a cellulose ester, the thickness of the layer (A) is from 0.01 to 5 ?m, and the open pore ratio H.sub.A of the layer (A) and the open pore ratio H.sub.B of the layer (B) satisfy H.sub.A<H.sub.B.

Problems that the invention is to solve is to provide a composite hollow fiber membrane being excellent in separation performance and permeation performance, having high membrane strength, and capable of being easily produced, and a method for producing the same. The present invention relates to a composite hollow fiber membrane including at least a layer (A) and a layer (B), in which the composite hollow fiber membrane has an outer diameter of 20 to 350 ?m and an inner diameter of 14 to 250 ?m, the tensile modulus of the composite hollow fiber membrane is from 1,000 to 6,500 MPa, the layer (A) contains a cellulose ester, the thickness of the layer (A) is from 0.01 to 5 ?m, and the open pore ratio H.sub.A of the layer (A) and the open pore ratio H.sub.B of the layer (B) satisfy H.sub.A<H.sub.B.

Disclosed is a method and apparatus for manufacturing a continuous web of polymeric membrane and for continuous downstream processing of said web. The apparatus (10) comprises: a casting station (20) for casting the continuous web (M); a carrier (24) for carrying the web downstream; a membrane drier (30) downstream of the carrier, for drying the web; and a brushing station (40) downstream of the drier for brushing the web. Said drier is located immediately downstream of the carrier, and upstream of said brushing station. The apparatus (10) further includes an additional drying station (50) downstream of the brushing station (40). Brushing after drying retains more surfactant in the membrane which is useful for certain applications. In addition, initial drying eliminates virtually all solvents from the membrane, but leaves some non-solvent (e.g. water) within it, which in turn fixes the surfactant on the nitrocellulose fibers, which improves significantly the consistency and reproducibility of the membrane.

The present disclosure relates to an exosome isolation method, more specifically, a method of isolating exosomes with high efficiency and high purity, including deproteinization, exosome aggregation, exosome binding, and exosome isolation. The method of isolating exosomes according to the present disclosure may be applied to all samples, such as body fluids and cell culture fluids, and thus, is characterized as a technique applicable to samples universally, and since total time required for exosome isolation is within 40 minutes, the method is time efficient, and since the method is capable of isolating 25 times more exosomes or greater than ultracentrifugation, the method may isolate exosomes with high efficiency and high purity. Therefore, the isolation method of the present disclosure and the exosomes isolated by the method are expected to be widely applicable in research on diagnosis or treatment methods requiring high-purity exosomes.

The present disclosure relates to an exosome isolation method, more specifically, a method of isolating exosomes with high efficiency and high purity, including deproteinization, exosome aggregation, exosome binding, and exosome isolation. The method of isolating exosomes according to the present disclosure may be applied to all samples, such as body fluids and cell culture fluids, and thus, is characterized as a technique applicable to samples universally, and since total time required for exosome isolation is within 40 minutes, the method is time efficient, and since the method is capable of isolating 25 times more exosomes or greater than ultracentrifugation, the method may isolate exosomes with high efficiency and high purity. Therefore, the isolation method of the present disclosure and the exosomes isolated by the method are expected to be widely applicable in research on diagnosis or treatment methods requiring high-purity exosomes.

Presented herein are membranes for use in separating solids including salts from water. One application of such membranes is in a sub-surface irrigation system that that utilizes a saline or tainted water as a feed source. In various embodiments, the membranes operate on a solution diffusion principle. In other embodiments the membranes operate on an ultrafiltration principle and/or a solution diffusion principle. In any embodiment, the membranes operate similar to pevaporation membranes suitable for non-pressure driven systems. The membranes are designed to provide increased flux rate while separating solids such as salts from water.