An apparatus to realize personalized cosmetic compositions including a formula supply assembly having a plurality of additive reservoirs that contains a plurality of additive substances, a plurality of additive pumps that supplies selected additive quantities of the plurality of additive substances, a base reservoir that contains a base substance, and a base pump that supplies a base quantity of the base substance and a mixing assembly having an additive inlet that receives the selected additive quantities, a base inlet that receives the base quantity, and a mixing channel that mixes the additive quantities with the base quantity to form the personalized cosmetic compositions.

In a method of detecting a test substance, a test substance is detected using a sample analysis cartridge supplied with a sample. The sample analysis cartridge includes: a passage part having a gas-phase space; and liquid containers communicating with the passage part through openings. The liquid containers include: a first liquid container containing a first liquid containing magnetic particles; and a second liquid container containing a second liquid containing a labeled substance. The magnetic particles are sequentially transported to the liquid containers through the gas-phase space in the passage part. Thus, the magnetic particles carry a complex of the test substance and the labeled substance. The test substance is detected based on the labeled substance in the complex.

A mixing device includes a mixing cavity having a partially open wall and a closed wall. In certain examples, the partially open wall and the closed wall are two separately formed pieces. A downstream side of the mixing device is shaped so as to define a helicoidal groove for circumferentially guiding gas from an outlet opening of the mixing cavity in a downstream direction. An injector sprays reactant into the mixing cavity.

An adapter for connecting one or more storage containers with a syringe is described. The adapter includes a first port that provide a connection with a first container volume, a second port that provides a connection with a second container volume, a third port that provides a connection to a syringe. The adapter further includes a mixing channel extending from a first end in fluid communication with the third port to a second end. The mixing channel includes a tortuous path along at least a portion of its length. The mixing channel enables two constituents of a pharmaceutical complex to be mixed through the mixing channel to form the pharmaceutical complex. Also disclosed is a system including such an adapter, a method of mixing two constituents of a pharmaceutical complex via such an adapter and a method of manufacturing such an adapter.

There is disclosed a capillary microfluidic circuit including a main channel communicating with a flow inducing element. The main channel has intermediary inlets. Reservoirs for containing one or more liquids prior to being drawn into the main channel. The reservoirs include a first reservoir and at least a second reservoir. Each of the reservoirs has an upstream end connectable to vents for filling the reservoirs with the one or more liquids and a downstream end. The downstream end of each of the reservoirs is connected to the intermediary inlets of the main channel A conduit is disposed between the first reservoir and the a least a second reservoir. The conduit links the downstream end of the first reservoir with the upstream end of the at least a second reservoir.

Limit size lipid nanoparticles, methods for using the lipid nanoparticles, and methods and systems for making limit size lipid nanoparticles.

A diffusion system comprising an upper unit and a lower unit. The upper unit comprises a series of tubing that is situated so as to effectuate collision of the fluid and air molecules. The upper unit uses vortex winding and unwinding and pressure gradients to avoid gas and liquid separation to accomplish successful collisions between a gas and a liquid. The lower unit comprises a filtering system, liquid intake system, air intake system, and submersible liquid transportation system.

A microfluidic apparatus includes a substrate defining a microchannel having inlet and an outlet defining a length of the microchannel. The microchannel has a main channel extending from the inlet to the outlet, and a plurality of side cavities extending from the main channel. The cavities are in fluid communication with the main channel. A method includes introducing a sample into the microchannel through the inlet to fill the entire microchannel, and then introducing a solvent into the microchannel through the inlet at a controlled flow rate and inlet pressure. A developed solvent front then moves along the main channel from the inlet to the outlet while displacing the sample in the main channel. Images of the microchannel are acquired as the front moves, and a miscibility condition is determined based on the images.

The subject matter of this specification can be embodied in, among other things, a gas mixer that includes a convergent-divergent nozzle comprising a convergent portion and a divergent portion and defining a first gas flow path, an air housing comprising an air inlet configured to supply air to the first gas flow path upstream of the convergent-divergent nozzle, a gas housing defining a second gas flow path and including a first gas inlet configured to receive a secondary gas and allow the secondary gas into a second gas flow path, and a gas nozzle positioned parallel to and centrally within the first gas flow path in a convergent portion of the convergent-divergent nozzle, the gas nozzle configured to supply the secondary gas to the first gas flow path upstream of the divergent portion.

A portable foam brush assembly having a base having a soap supply, a water supply, and an electrical supply. A foam brush wand is detachably dockable to the base and in electrical and fluid communication with the foam brush wand having battery pack, a peristaltic pump, a reservoir chamber, a foaming chamber, an air pump, a brush and a momentary release switch. The base water supply and the base soap supply, when activated, are configured to travel by a water supply hose and a soap supply hose to a tee in the base where they are combined in a combined hose to a base quick coupler that is connectable to a reciprocal foam brush wand quick coupler, which has a foam brush wand hose to deliver the water soap mixture to bladder in the foam brush wand.