This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals. In some embodiments, reactor systems comprising a mobile carriage assembly; a disposable reaction container removably attached to the carriage assembly; and, a carriage holder into which the mobile carriage assembly may be removably inserted are provided.

Disclosed herein is a water treatment system. The system comprises a mixing station in which coagulant is mixed into water for treatment in the system. The system comprises a floccule accumulation station in which the building of floccules in the water/coagulant mixture is promoted. The system comprises a settlement station in which the floccules are allowed to settle. The mixing station, floccule accumulation station and settlement station comprise one or more reservoirs, wherein at least one of the one or more reservoirs is an intermediate bulk container.

The present invention relates to a high-speed continuous mixing apparatus comprising: a motor stage (3), an intermediate stage (4) and a final stage (5) arranged in alignment with each other; a mixing chamber (25) in the final stage (5); a mixing shaft (7) rotating with respect to the mixing chamber (25) and provided with radial pins (9); an electric motor (6) in the motor stage (3) for driving the mixing shaft (7) in rotation; a coupling joint or fitting (27) between the electric motor (6) and the mixing shaft (7) in the intermediate stage and a pair of rolling bearings (2, 21) for the support of said mixing shaft (7) in said intermediate stage (4). This configuration allows a direct coupling between motor and mixing shaft without using an intermediate reducer.

A dynamic mixer head has a connecting cover, a rotor and a housing. The connecting cover has a rotor opening. The rotor has a first rotor axle mounted in the rotor opening and a mixing rotor connected with the first rotor axle. The mixing rotor has multiple vaned inner rotors with quarter-circle shaped multiple vanes and a vaned front rotor opposite to a second rotor axle of the mixing rotor with multiple vanes complementary to the multiple vanes of the multiple vaned inner rotors. The housing mounted to the connecting cover has at least two grooves disposed on the circular partition. Each of the at least two grooves has a spacer along each of the at least two grooves. The dynamic mixer head can enhance the mixing effect of two different component substances during rotation.

Methods and apparatus for the treatment of animal waste are disclosed, together with a treated animal waste and fertilizer and growth media products derived therefrom.

A mixing device includes a base, shaft, impeller sleeve, and impeller blades. The base can be constructed for releasable attachment to an opening of a container, such as a 55-gallon drum. The shaft extends from the base and is coupled thereto such that rotation can be transmitted to the shaft by way of or through the base. The impeller sleeve is mounted on the shaft and supports the impeller blades. Each impeller blade includes an attachment leg and a stirring leg extending from the attachment leg. The impeller blades are supported so as to transition from a collapsed position with the stirring leg proximal to a central axis of the shaft to an extended position with the stirring leg distal from the central axis when the shaft is rotated. Each impeller blade can be formed of a plastic, such as a glass-filled polypropylene or glass-filled nylon.

The present disclosure is directed to compositions and methods for making a pharmaceutical composition by thermokinetic compounding, wherein the compositions include one or more thermolabile components, for example one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients. The methods comprise thermokinetic processing of the thermolabile components into a composite by blending certain thermolabile components in a thermokinetic mixer using multiple speeds during a single, rotationally continuous operation. The composite can be further processed into pharmaceutical compositions by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.

A mixing device includes a base, shaft, impeller sleeve, and impeller blades. The base can be constructed for releasable attachment to an opening of a container, such as a 55-gallon drum. The shaft extends from the base and is coupled thereto such that rotation can be transmitted to the shaft by way of or through the base. The impeller sleeve is mounted on the shaft and supports the impeller blades. Each impeller blade includes an attachment leg and a stirring leg extending from the attachment leg. The impeller blades are supported so as to transition from a collapsed position with the stirring leg proximal to a central axis of the shaft to an extended position with the stirring leg distal from the central axis when the shaft is rotated. Each impeller blade can be formed of a plastic, such as a glass-filled polypropylene or glass-filled nylon.

A dynamic mixer head has a cover, a housing, and a rotor. The cover has a first base board, two inlets, and a holding cylinder. A rotor holding channel is formed in the holding cylinder and a sealing portion protrudes from an inner wall surface of the rotor holding channel. The housing is mounted on the cover and has a second base board, a mixing cylinder, and an inner channel. The inner channel is formed in the mixing cylinder and fluidly communicates with an outlet. The rotor is rotatably disposed in the inner channel and has a rotor axle and a mixing rod. The rotor axle is disposed through the rotor holding channel, contacts and is surrounded by the sealing portion. The mixing rod has multiple first vanes. The dynamic mixer head does not need two sealing structures and tight fitting of the rotor and the holding cylinder.