Methods and systems for chromatography are disclosed that employ a flexible container configured to fit within a support structure and adapted to receive a filtration or absorptive medium. The flexible container can include at least one inlet, at least one outlet, and a separation barrier peripherally sealed within the container to separate the container into a resin containing portion and a drainage portion. The barrier can be configured to exclude the resin material from the drainage portion while allowing fluids to pass therethrough. The disposable chromatography system can further include one or more agitators disposed within the flexible container and adjustably configured to be raised or lowered in the flexible container. When the agitator is in the raised position, the resin packing material can operate in a settled, packed-bed configuration. Alternatively, the agitator in the lowered position permits the chromatography resin packing material to operate in a mixed, slurry configuration.

A method for connecting functional elements (14) to a shaft (10, having the following steps: (a) forming elevations (12) for receiving the functional elements (14), said elevations (12) being machined out of the shaft (10) by removing material, and (b) welding the functional elements (14) to the elevations (12) on the shaft (10).

A packaging for a flexible container, in particular for a disposable bag for use in a bioreactor, including a bottom part for fixing a first portion of the container, a ceiling part for fixing an opposite second portion of the container, a receiving space which on a first side is defined by the bottom part and on an opposite second side is defined by the ceiling part, and struts arranged between the bottom part and the ceiling part, which fix a defined distance between the bottom part and the ceiling part.

A pulping machine includes a frame, a mixing device, and a dispersing device. The frame has a mixing chamber and a dispersing chamber, the mixing device is accommodated in the mixing chamber, the dispersing device is accommodated in the dispersing chamber; the dispersing chamber has a liquid inlet, the mixing chamber has a liquid outlet, the liquid inlet, the dispersing chamber, the mixing chamber and the liquid outlet are sequentially communicated; the mixing chamber also has a powder material inlet, the powder material inlet, the mixing chamber and the liquid outlet are sequentially communicated along a flow direction of powder material; the liquid outlet is connected with a filter device.

Blender and food processing devices dampen impact forces between a blending blade and a blending jar. One blender includes a blender base and a blending jar that has a seal opening. A blending blade assembly in the jar includes a blending blade, a jar shaft attached to the blending blade and extending through the seal opening, a circular motion guide positioned around the jar shaft, and a jar seal positioned between the circular motion guide and the seal opening. The jar seal prevents contact between the circular motion guide and the seal opening and dampens forces induced by relative motion between the seal opening and the blending blade, jar shaft, and/or circular motion guide. The dampening may reduce wear or damage to the jar and may improve quality of the blending jar and blade assembly.

A beverage stirring assembly for selectively stirring a liquid in a container includes a container that may contain a liquid. A stirring unit is removably coupled to the container and the stirring unit is selectively manipulated. The stirring unit stirs the liquid when the stirring unit is manipulated. Moreover, the stirring unit is selectively removed from the container thereby facilitating an interior of the container to be washed.

Methods and systems for chromatography are disclosed that employ a flexible container configured to fit within a support structure and adapted to receive a filtration or absorptive medium, such as a chromatography resin. The flexible container can include at least one inlet, at least one outlet, and a separation barrier peripherally sealed within the container to separate the container into a resin containing portion and a drainage portion. The barrier can be configured to exclude the resin material from the drainage portion during use while allowing fluids to pass therethrough. The disposable chromatography system can further include one or more agitators disposed within the flexible container and adjustably configured to be raised or lowered in the flexible container. When the agitator is in the raised position, the resin packing material can operate in a settled, packed-bed configuration. Alternatively, the agitator in the lowered position permits the chromatography resin packing material to operate in a mixed, slurry configuration.

The present invention concerns a mixing shaft comprising a tool holder and a mixing blade, wherein the tool holder has a recess in which a portion of the mixing blade is fixed. To provide a simple mixing shaft, there is proposed a clamping portion fitted into the recess for fixing the mixing blade portion in the recess, wherein the clamping portion, the recess and the mixing blade portion are of such a configuration that a force-locking connection of the mixing blade in the recess is implemented by means of the clamping portion.

A packaging for a flexible container, in particular for a disposable bag for use in a bioreactor, comprises a bottom part for fixing a first portion of the container, a ceiling part for fixing an opposite second portion of the container, a receiving space which on a first side is defined by the bottom part and on an opposite second side is defined by the ceiling part, and struts arranged between the bottom part and the ceiling part, which fix a defined distance between the bottom part and the ceiling part.

A dynamic mixer dispense valve and metering apparatus suitable for use in mixing and applying high viscosity, disparate viscosity, high ratio and/or relatively immiscible two part compounds that exhibit short cure times includes a housing supporting a pair of valve assemblies each coupled to respective sources of base and accelerator components. A pair of pneumatic valve actuator s control the operation of the valve assemblies to control the flow of components into a mixing chamber. Within the mixing chamber a mixer impeller is rotatably supported and coupled to a source of rotational power. An additional pneumatic valve actuator combination operates a further flow control to prevent undesired material loss following a shot cycle.