A fluid transfer assembly for single use bioreactors includes a fluid transfer housing that can be mounted to the impeller shaft using a bearing that places the fluid transfer assembly directly below the lowest impeller but allows the impeller shaft to spin inside independently of the fluid transfer assembly. A fluid conduit connects the fluid transfer housing to a port in the single use bag wall which allows fluids to be introduced into the sparger and which also helps prevent the fluid transfer assembly from rotating with the impeller shaft.

A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, is coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.

A system can include a dry powder mixing tank, a first powder input, a second powder input, a powder output, and a detection device. The first powder input and the second powder input can introduce powders containing different substances that become mixed in the dry powder mixing tank. The detection device can detect information about amounts of different substances in a blend of powder moved out of the tank by the powder output. In some aspects, portions of the blend that do not satisfy parameters for the blend can be diverted from a receptacle for the blend based on the detected information.

A single-use bioreactor is provided. The single-use bioreactor may include a bioprocess container, a shell, at least one agitator, at least one sparger, at least one gas filter inlet port for the sparger(s) and headspace overlay, at least one fill port, at least one harvest port, at least one sample port, and at least one probe. In examples, at least one controller may monitor and control one or more parameters associated with the single-use bioreactor A method to cultivate and propagate mammalian cells is also provided. The method may include cultivating under suitable conditions and in a suitable culture medium in a first single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a second single-use bioreactor, transferring the medium containing the cells obtained by propagation from the at least one mammalian cell is into a third single-use bioreactor, and cultivating the cells in the third bioreactor.

A method for stirring resin pellets, which includes stirring adhesive resin pellets in a liquid in a stirring tank equipped with a stirring impeller, under the condition satisfying the following relational expression (I):

[00001]$\begin{array}{cc}\frac{\rho .Math..Math.{\left({\mathrm{Np}}^{1/3}.Math.\mathrm{nD}\right)}^2}{\Delta .Math..Math.\mathrm{pgdp}}\geqq 10& \left(I\right)\end{array}$

wherein ρ is the density of the liquid (kg/m.sup.3), Np is the power number of the stirring impeller, n is the rotational speed (1/s), D is the diameter of the stirring impeller (m), Δρ is the difference in density between the resin pellets and the liquid (kg/m.sup.3), g is the gravitational acceleration (m/s.sup.2), and dp is the particle diameter of the resin pellets (m).

The present invention provides a beverage machine with at least three distinct zones 1, 3, 4. A first zone 1 for storing a liquid or semi-liquid product at ambient temperature, a second zone 3 for processing the stored product, in particular for cooling the product to a predetermined serving temperature, and a third zone 4 for storing the cooled product and maintaining it at the predetermined serving temperature. From the third zone 4 an iced beverage can be dispensed.

A stirring tool for a stirrer for stirring a mixture comprises a connecting element for connecting the stirring tool to a stirring drive, drivable about a rotational axis, of the stirrer, a carrier ring, a plurality of stirring spokes disposed between the connecting element and the carrier ring, and at least one stirring boss, which projects radially on the carrier ring, wherein two adjacent stirring spokes are arranged mutually offset in the direction of the rotational axis.

A vertical household noodle maker includes a base, a stirring container connected to the base, a stirring rod longitudinally arranged in the stirring container, an extrusion cylinder horizontally arranged at one side below the stirring container, a spiral rod arranged in the extrusion cylinder, an extrusion die and a control unit. The stirring rod includes a rod body and a stirring blade. The motor rotates the stirring rod and the spiral rod, and a feeding inlet in communication with the extrusion cylinder is provided at a bottom of the stirring container. An inner wall of the stirring container is provided with a cutting rod, and a projection of the cutting rod at least partially overlaps with a projection of the stirring blade in the horizontal direction when the stirring blade is driven by the motor to rotate to a position of the cutting rod.

The invention relates to a process for preparing a solid support for a procatalyst suitable for preparing a catalyst composition for olefin polymerization, said process for preparing said solid support comprising reacting a compound R.sup.4.sub.zMgX.sup.4.sub.2-z with a silane compound Si(OR.sup.5).sub.4-n(R.sup.6).sub.n in a solvent and mixing the resulting mixture with a mixing device and at a certain mixing speed in order to give a solid support Mg(OR.sup.1).sub.xX.sup.1.sub.2-x said solid support obtained having an average particle size of at most 17 μm, preferably at most 16 or 14 μm, more preferably at most 12 μm. The invention further relates to a solid support, a process for preparing a procatalyst and said procatalyst as well as polyolefins obtained using said procatalyst.

The invention pertains to a rotary mixer and disperser head consisting of a shaft to which is connected a mixing chamber that is to be disposed into a vat or the like for dispersing, dissolving or blending of solids liquids or gasses with other liquids. The mixing chamber has secured to its upper and lower ends a plurality of impeller blades which have an end thereof located outside the mixing chamber to direct material into the mixing chamber and out through openings in the side wall of the mixing chamber during the mixing and dispersing thereof. The mixer and disperser head also comprises shear arms having a sharpened leading edge, thereby providing an additional initial shear zone. The specific mixing chamber and its configuration provide for a very efficient mixing operation.