Biomaterials, in particular bone foams, a process for preparing such materials as well as an applicator for applying the biomaterials directly to the patient's application site, and the use of a composition comprising water, a surfactant and a propellant in the preparation of a bone foam for the preparation of a calcium phosphate foam wherein the foam is obtainable by the mixture of at least two phases, a first phase comprising water and optionally a propellant, a second phase comprising one or more sources for calcium and/or phosphate, and wherein the foaming is performed during the mixture of the at least two phases to provide an improved calcium phosphate foam, process for the preparation of a calcium phosphate foam, use of a composition, solid state structure, calcium phosphate cement foam and bone foam applicator.

A flow shifter baffle for mixing a fluid flow having at least two components, a static mixer and method of mixing. The flow shifter baffle includes a double divider wall element adjacent to a leading edge and a plurality of occluding walls coupled to the double divider wall element. The double divider wall element includes first and second generally parallel walls which extend across the entire transverse flow cross-section. The double divider wall element is configured to divide the fluid flow into a central flow portion and first and second peripheral flow portions. This division of the fluid flow using the double divider wall element and the plurality of occluding walls improves the mixing of separate components by producing a greater number of layers with less jumbling of the layers, when a layered composition of multiple components is delivered into the flow shifter baffle.

A bone filler mixing and delivery device includes a mixing section adapted to mix components to form bone filler. A syringe barrel is coupled to the mixing section and has an opening through which the bone filler can be dispensed. A controllable portal can be manipulated to open a flow path between the mixing section and the syringe barrel. A plunger assembly is adapted to extend telescopically in an axial direction through the syringe barrel to dispense the bone filler through the opening.

A delivery system of a colored product having a target color including an application device of the colored product, at least two reservoirs each containing a respective base product, a calculation module configured to receive the information concerning the target color and to determine a composition of the colored product from the base products contained in the reservoirs, at least one metering device in fluid communication with the reservoirs, configured to deposit on the application device a dose of each of the base products corresponding to the determined composition, a mixing device configured to mix the doses of base products deposited on the application device. Also, a method for delivering a colored product having a target color via the delivery system. Finally, the use of the system for applications requiring the delivery of a colored product having a target color.

Disclosed is a double chamber container. The first chamber comprises a stopper coupled to a first end and a cover coupled to a second end. The second chamber comprises a plunger coupled to one end and an open second end. The first chamber is coupled to the second chamber such that the first end of the first chamber is coupled to the second end of the second chamber.

The present disclosure relates to systems and methods for mixing and injecting fluid treatment, such as cement to treat bone or hard tissue. In some embodiments, a mixing apparatus may facilitate mixing within a syringe. Additionally, the syringe may be configured to extract bone cement from a cement mixer. A syringe for mixing and injecting cement may include a detachable handle that may be detached after extracting bone cement from a mixer to facilitate coupling to a high-pressure syringe for injection.

A bone material comprising a coherent mass of cartridge milled and demineralized bone fibers is provided, the coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a bone material comprising a lyophilized coherent mass of cartridge milled and demineralized bone fibers is provided, the lyophilized coherent mass having no binder disposed in or on the coherent mass. In some embodiments, a method of making an implantable bone material is provided, the method comprising drying a coherent mass of cartridge milled and demineralized bone fibers, the coherent mass having no binder disposed in or on the coherent mass.

Biomaterials, in particular bone foams, a process for preparing such materials as well as an applicator for applying the biomaterials directly to the patient's application site, and the use of a composition comprising water, a surfactant and a propellant in the preparation of a bone foam for the preparation of a calcium phosphate foam wherein the foam is obtainable by the mixture of at least two phases, a first phase comprising water and optionally a propellant, a second phase comprising one or more sources for calcium and/or phosphate, and wherein the foaming is performed during the mixture of the at least two phases to provide an improved calcium phosphate foam, process for the preparation of a calcium phosphate foam, use of a composition, solid state structure, calcium phosphate cement foam and bone foam applicator.

A manifold for loading plural cannulae with a substance is described. The manifold includes a housing with a plurality of channels that route the flow of the mixed substance from a single central channel to multiple sub-channels for the simultaneous filling of attached cannulae. Each sub-channel extends to a fitting to which a cannula may be attached. The fittings are rotatably mounted to the housing. A lock assembly holds the cannulae to the individual fittings are so that when a cannula is removed from a fitting, the fitting rotates so as to close the fluid path from the sub-channel. In order to attach a second cannula to the same fitting the lock system requires the fitting to be rotates into a position in which the fluid communications path from the associated sub-channel is reopened.

Storage and mixing systems and methods for pasty multicomponent polymethylmethacrylate bone cements, the systems and methods comprise a first tubular cartridge with a first cylindrical internal space containing a first starting component, a first dispensing plunger, a second tubular cartridge that is arranged within the first tubular cartridge. The external wall of the second cartridge touches against the internal wall of the first cartridge and is attached to the internal wall of the first cartridge, whereby the second cartridge contains a second starting component and has a second dispensing plunger arranged in it, whereby a pressing device with a clamping edge for compressing the second cartridge that can be propelled axially in the internal space of the first cartridge is arranged, as seen from the cartridge head, behind the first dispensing plunger and the second dispensing plunger. The pressing device can be propelled appropriately in the direction of the cartridge head such that the second cartridge is being progressively compressed axially during the motion of the pressing device such that, in the process, the first dispensing plunger and the second dispensing plunger are propelled in the direction of the cartridge head.