The present set of embodiments relate to a bioproduction system, method, and apparatus for mixing a fluid. The bioproduction mixing system includes an offset helical assembly having a stabilizer and impeller for mixing a fluid within a flexible compartment The bioproduction mixing system is designed for efficient mixing of the fluid and for use with a variety of different impellers that can be located at different locations according to the volume and shape characteristics of the flexible compartment. The bioproduction mixing system is optimized to eliminate stagnation zones while maximizing bulk fluid flow.

The present set of embodiments relate a system, method, and various devices for installation of a bioproduction system. The bioproduction system includes a rigid housing having a moveable platform to assist in the installation of a bioprocessing container within. The system also includes mounting systems for a variety of peripherals originating from the flexible container while safeguarding operators. More specifically, the system includes systems and methods for mounting bearings, organizing tube sets, and placement of the flexible container in its proper orientation.

The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

Systems and methods for mixing are disclosed. A system for mixing can include a mixer vessel that defines a chamber. The system can include a first mixing blade to cause a first rotational movement to mix a material within the chamber. The system can include a second mixing blade to cause a second rotational movement to mix the material within the chamber of the mixer vessel. The system can include a mixing element to cause a third rotational movement to mix the material within the chamber of the mixer vessel. The system can include the first mixing blade to cause the first rotational movement independent from at least one of the second rotational movement and the third rotational movement.

A manual mixer serves to facilitate mixing and agitating materials for use during surgery. For example, the manual mixer includes a body portion defining an interior area, a mixing assembly provided in the interior area of the body portion, a crank assembly for actuating the mixing assembly, and a valve assembly. The mixing assembly serves to mix and agitate the materials provided in the interior through rotation of a plunger portion and a spring attached thereto, and through upwards and downwards movement of the plunger portion in the interior area. Rotation of the crank assembly serves to rotate the plunger portion and the spring attached thereto, and effectuate upwards and downwards movement of the plunger portion. The valve assembly can be opened to facilitate dispensing of the materials from the interior area.

An agitator for being disposed in a container and rotated to agitate fluid in the container includes a shaft and an impeller attached thereto. The shaft, being supported relative to the container, provides an input for attachment of a rotation mechanism for causing rotation of the impeller and shaft. The impeller includes an impeller body defined by a hub portion for receiving and being mounted to the shaft, and a plurality of blades extending radially outwardly from a longitudinal axis of the hub portion. The impeller body is a single piece of unitary construction, such as where the plurality of blades are formed in a manner that the blades are integral with the hub portion at the formation of the blades.

Apparatus that mixes non-homogenous fluid. A threaded shaft within a housing circulates fluid within a container to effect mixing. In one embodiment, when placed in a container of fluid, the housing the fluid is recirculated through opposing ends of the housing. In an embodiment of a related method for mixing, a pump housing containing a screw journaled for rotation receives fluid within a container and conveys the fluid therethrough to circulate a fluid portion in the container along an exterior surface of the housing for mixing with another fluid portion to improve fluid homogeneity. After mixing, the portion of the fluid which first circulates through the housing may recirculate through the housing with said another portion of the fluid. The fluid may be continuously mixed and recirculated through the housing.

A manual mixer serves to facilitate mixing and agitating materials for use during surgery. For example, the manual mixer includes a body portion defining an interior area, a mixing assembly provided in the interior area of the body portion, a crank assembly for actuating the mixing assembly, and a valve assembly. The mixing assembly serves to mix and agitate the materials provided in the interior through rotation of a plunger portion and a spring attached thereto, and through upwards and downwards movement of the plunger portion in the interior area. Rotation of the crank assembly serves to rotate the plunger portion and the spring attached thereto, and effectuate upwards and downwards movement of the plunger portion. The valve assembly can be opened to facilitate dispensing of the materials from the interior area.

The present invention relates to a magnetic mixer capable of minimizing mixing of foreign substances, which are generated in components of the magnetic mixer, of a liquid to be mixed, having a simple structure for cleansing a structure supporting an impeller shaft, and capable of securing a sufficient output when a large-scale mixing system with an impeller shaft is configured; and a mixing system including the same.

The present invention discloses a sparkling water machine capable of achieving automatic resetting from gas inflow, comprising a main machine, a sub-machine, a gas inflow main body, a gas path main body, a button, a gas inflow pressure rod, a gas pressure chamber, a gas pressure valve body, a gas pressure valve rod, a first resetting device, a second resetting device and a gas inflow connecting rod hook, and the gas inflow pressure rod is provided with a through hole. When in use, gas is supplied to a carbon dioxide gas cylinder through the button, and the gas inflow pressure rod is fixed under the action of the second resetting device. When a gas pressure in a sparkling water bottle reaches a specified value, a driving end of the gas inflow connecting rod hook is pressed, thereby achieving automatic resetting and stopping gas inflow.