A device for driving a plurality of rotatable agitators for use in a static batch reactor system, a reactor bottle cap for use with the rotatable agitator driving device and a static batch reactor system which includes the rotatable agitator driving device and bottles fitted with the reactor bottle cap are disclosed. The rotatable agitator driving device includes a planar case having first and second opposite faces, a plurality of drive heads projecting from the case through the second face and a gear train protectively housed in the case. The gear train includes a driver gear having a coupling for receiving drive from a motor, a set of idler gears and a set of driven gears. Each driven gear attached to a respective drive head for driving a rotatable agitator. The gear train is configured to cause the drive heads to rotate at the same rate.

Provided is a liquid stirring apparatus of the type using a non-contact drive mechanism (4) where the stirrer is driven through a magnetic drive effect without a mechanical connection member intruding through a wall of a container (2) for receiving a liquid to be stirred. The stirrer is received in use within the container (2). The non-connect driving mechanism (4) is arranged externally of the container (2). A holder is provided for positioning the stirrer within the container (2) where the holder is not integrally formed with the container (2), but is a separate component therefrom. The holder is not affixed to the container (2), but locates within the container (2) such that it positions the stirrer adjacent a wall of the container (2) near to the external location of the non-contact drive mechanism (4). The holder is manually removable from the container (2) and the stirrer is manually removable from the holder for cleaning.

The provided are a thickening device and method for uniform solidification of composite lost circulation material made up of liquid and granular lost circulation materials. The thickening device includes a base. The base is provided with a side wall; an upper end of the side wall is provided with a detachable top cover; the base, the side wall, and the top cover form a sealed chamber; the base is provided with a rotating support platform; the rotating support platform is provided with a detachable slurry cup; the slurry cup is provided therein with agitating shafts; the agitating shafts each are provided with a blade; a top end of the agitating shaft is connected to a threaded rod through a ball head connector; an upper end of the agitating shaft is provided with a second gear; and the threaded rod is provided with a second limit platform.

The provided are a thickening device and method for uniform solidification of composite lost circulation material made up of liquid and granular lost circulation materials. The thickening device includes a base. The base is provided with a side wall; an upper end of the side wall is provided with a detachable top cover; the base, the side wall, and the top cover form a sealed chamber; the base is provided with a rotating support platform; the rotating support platform is provided with a detachable slurry cup; the slurry cup is provided therein with agitating shafts; the agitating shafts each are provided with a blade; a top end of the agitating shaft is connected to a threaded rod through a ball head connector; an upper end of the agitating shaft is provided with a second gear, and the threaded rod is provided with a second limit platform.

The present set of embodiments relate to a bioproduction system, method, and apparatus for creating a scalable bioreactor system. Specifically, the present set of embodiments enable the determination of bioreaction performance characteristics of a commercial scale by matching operational parameters between a small test scale bioreaction to that of a commercial scale bioreaction. The system and methods do not rely on simply making bioreactor apparatuses across scales the same dimensionally which would not account for differences in fluid dynamic properties between very small to very large volumes, but requires tuning of a variety of systems (mixing assembly, sparger system, and headspace airflow system) in conjunction with one another to achieve predictive outcomes.

One variation of a mixing system includes: a container configured to store consumable beverages; a lid; and a mixer. The lid is configured to transiently couple to the container and includes: a housing; a mixer receptacle; a set of user controls arranged on an outer face of the lid; a set of electronics arranged within the housing and including a motor, a controller configured to actuate the motor responsive to selection of the set of user controls, and a power supply configured to supply power to the motor and the controller; and a set of supports arranged between the motor and walls of the housing and configured to absorb energy output by the motor. The mixer includes: a connector section configured to engage the mixer receptacle to couple the mixer to the motor; and a mixing section configured to mix ingredients in the container responsive to actuation of the motor.

A bioproduction mixing system includes a flexible compartment having a first end, a second end, and a sidewall extending therebetween, a center axis passing through the flexible compartment between the first end and the second end. A helical assembly is disposed within the flexible compartment and is suspended between the first end and the second end, the helical assembly being offset from the center axis of the flexible compartment.

A mixing device with rotatable container, which can simultaneously meet the sealing, material mixing and cleaning requirements of large-sized mixers, includes a fixed container having a top opening; a mixing container having a top opening and a bottom material outlet, rotatably connected to and positioned inside the fixed container; a driving cover configured to open or close the top opening of the fixed container; a mixing container cover integrally and coaxially arranged with the driving cover and to rotate relative to the driving cover, configured to open or close the top opening of the mixing container and to rotate synchronously with the mixing container after the mixing container is covered by the mixing container cover; and a discharge and sealing mechanism arranged coaxially with the driving cover to form an integral body, and configured to open or close the material outlet from inside.

A mixing device with rotatable container, which can simultaneously meet the sealing, material mixing and cleaning requirements of large-sized mixers, includes a fixed container having a top opening; a mixing container having a top opening and a bottom material outlet, rotatably connected to and positioned inside the fixed container; a driving cover configured to open or close the top opening of the fixed container; a mixing container cover integrally and coaxially arranged with the driving cover and to rotate relative to the driving cover, configured to open or close the top opening of the mixing container and to rotate synchronously with the mixing container after the mixing container is covered by the mixing container cover; and a discharge and sealing mechanism arranged coaxially with the driving cover to form an integral body, and configured to open or close the material outlet from inside.

A method of installing a flexible bioprocess container in a bioprocessing system having a rigid housing with an interior compartment and extending between a top and an opposing base. The method includes coupling a first surface of the flexible bioprocess container to a moveable platform positioned within the interior compartment of the rigid housing; coupling a second surface of the flexible bioprocess container to the base of the rigid housing; and moving the movable platform relative to the rigid housing and toward the top of the rigid housing so as to at least partially expand the flexible bioprocess container within the interior compartment of the rigid housing.