Compositions and methods that utilize a combination of essential oils or other plant-derived extracts or compounds and an emulsifier as an antimicrobial are provided. In some embodiments the compositions further include ozone. In some embodiments, the composition includes one or more plant essential oils, plant extracts, or plant-derived compounds, or combinations thereof, and an emulsifier (such as a saponin). The antimicrobial composition may also include water, peracetic acid, acetic acid, lactic acid, citric acid, and/or hydrogen peroxide. Methods of killing a microorganism, including contacting the microorganism with the disclosed antimicrobial compositions are also provided. The microorganism may be present on a food item or a food contact of non-food contact surface and may be in the form of a biofilm. In some examples, the antimicrobial composition is used one or more times (such as 1 to 5 times).

Agents and natural and synthetic formulations and extracts are useful in control of pathogen infection and infestation in humans, animals and plants, as well as pathogen contamination in environmental locales. A method inhibits growth or infection or infestation of a pathogen, including contacting the pathogen with an effective amount of a combination of a plant defensin or a functional natural or synthetic derivative or variant thereof and a non-defensin peptide, such as a cathelicidin peptide, a hairpin peptide, a hairpin peptide from which disulfide bridges have been removed, indolicidin, synthetic peptide CP-29, or a peptide derived from a cystatin. The combination of the defensin and peptide are synergistic compared to the use of each alone at the same individual dose as used in the combination.

Agents and natural and synthetic formulations and extracts are useful in control of pathogen infection and infestation in humans, animals and plants, as well as pathogen contamination in environmental locales. A method inhibits growth or infection or infestation of a pathogen, including contacting the pathogen with an effective amount of a combination of a plant defensin or a functional natural or synthetic derivative or variant thereof and a non-defensin peptide, such as a cathelicidin peptide, a hairpin peptide, a hairpin peptide from which disulfide bridges have been removed, indolicidin, synthetic peptide CP-29, or a peptide derived from a cystatin. The combination of the defensin and peptide are synergistic compared to the use of each alone at the same individual dose as used in the combination.

Agents and formulations and cells including plant extracts are useful in a method for controlling pathogen infestation in human and animal subjects. A method for inhibiting growth or infestation of a pathogen in or on a human or animal subject, includes contacting the pathogen with an effective amount of a combination of a plant defensin or a functional natural or synthetic derivative or variant thereof and either: (i) a proteinase inhibitor; or (ii) a chemical pathogenicidic or pathogenostatic agent; in a combined amount effective to inhibit growth or infestation of the pathogen.

Agents and formulations and cells including plant extracts are useful in a method for controlling pathogen infestation in human and animal subjects. A method for inhibiting growth or infestation of a pathogen in or on a human or animal subject, includes contacting the pathogen with an effective amount of a combination of a plant defensin or a functional natural or synthetic derivative or variant thereof and either: (i) a proteinase inhibitor; or (ii) a chemical pathogenicidic or pathogenostatic agent; in a combined amount effective to inhibit growth or infestation of the pathogen.

Repellents that contain wax, oil and a repelling agent containing pepper are disclosed. Systems of repellents applied to a substrate to repel pests are disclosed. Methods of forming wax and pepper-containing repellents and methods of repelling pests that include applying wax-containing repellents to substrates are disclosed.

Repellents that contain wax, oil and a repelling agent containing pepper are disclosed. Systems of repellents applied to a substrate to repel pests are disclosed. Methods of forming wax and pepper-containing repellents and methods of repelling pests that include applying wax-containing repellents to substrates are disclosed.

Repellents that contain wax, oil and a repelling agent containing pepper are disclosed. Systems of repellents applied to a substrate to repel pests are disclosed. Methods of forming wax and pepper-containing repellents and methods of repelling pests that include applying wax-containing repellents to substrates are disclosed.

Game attractant and varmint repellent compositions which can be applied to a wildlife feeder to attract game animals to the feeder via positive aromatic characteristics and simultaneously deter or repel feed scavenging varmint animals from the feeder via negative gustatory characteristics may include a composition mixture comprising at least one carrier in a quantity of from about 55% to about 95% by weight; at least one pepper in a quantity of from about 0.5% to about 25% by weight; at least one oil in a quantity of from about 2% to about 25% by weight; and at least one spice in a quantity of from about 2% to about 20% by weight. Game attractant and varmint repelling methods are also disclosed.

Game attractant and varmint repellent compositions which can be applied to a wildlife feeder to attract game animals to the feeder via positive aromatic characteristics and simultaneously deter or repel feed scavenging varmint animals from the feeder via negative gustatory characteristics may include a composition mixture comprising at least one carrier in a quantity of from about 55% to about 95% by weight; at least one pepper in a quantity of from about 0.5% to about 25% by weight; at least one oil in a quantity of from about 2% to about 25% by weight; and at least one spice in a quantity of from about 2% to about 20% by weight. Game attractant and varmint repelling methods are also disclosed.