Disclosed is a heat exchange module for use in a chemical, pharmaceutical or biological reactor system, the module configured to be disposed in the reactor system having a flexible single use container, and including at least one thermally conductive surface adapted to contact the flexible single use container to facilitate heat transfer, and a fluid circulation path through which a heat exchange fluid can be circulated.

This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals. In some embodiments, reactor systems comprising a mobile carriage assembly; a disposable reaction container removably attached to the carriage assembly; and, a carriage holder into which the mobile carriage assembly may be removably inserted are provided.

This disclosure describes an improved heat transfer system for use in reaction vessels used in chemical and biological processes. In one embodiment, a heat transfer baffle comprising two sub-assemblies adjoined to one another is provided.

A horizontal reactor equipped with a front cover and including a circular cylindrical rotating cage having multiple openings and rotated about a horizontal axis by a motor, a single horizontal rotary shaft mechanically connecting the rotating cage to the motor and extending towards the outside from the distal face of the housing, at least one bearing provided around the rotary shaft to hold it and guide it, and to support the weight of the rotating cage in cantilever, at least one removable basket having multiple openings and intended to be able to be introduced inside the rotating cage and to be removed through an open circular face of the rotating cage provided opposite the cover.

The present invention relates to novel microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the gastrointestinal tract at an elevated rate without causing undesirable side effects. The preferred formulations are designed avoid increase in pH of urine in patients and/or avoid potential entry of particles into the bloodstream of the patient. Also disclosed is a method for preparing high purity crystals of UZSi-9 exhibiting an enhanced level of potassium exchange capacity. These compositions are particularly useful in the therapeutic treatment of hyperkalemia.

A process involving the steps of: (a) supplying reactants to a reactor vessel (A); (b) optionally, supplying a solvent to the reactor vessel; (c) subjecting the contents of the reactor vessel to reactive conditions to obtain a product mixture (1) including a reaction product; (d) removing the product mixture (1) from the reactor vessel and supplying it to a decanter system (B); (e) in the decanter system, separating the reaction product from the product mixture by decantation and removal of a stream (2) including the reaction product; (f) removal of a stream (3) including the solvent from the decanter system; wherein at least one of the reactants supplied in step (a) is supplied in a form dissolved in a solvent, or a solvent is supplied in step (b).