A liquid amount control device includes a position detector, a pump, a driver and a controller. The pump is connected with a first tip and configured to suck up the liquid out of the test tube. The driver is connected with the pump and configured to drive the pump to move. The controller is configured to: (1) control the driver to drive a first suction end of the first tip to enter a detection region of the position detector to obtain an end height position of the first suction end; (2) control the driver to drive the first suction end of the first tip to enter the liquid by a first entering depth according to the end height position; and (3) control the pump to suck up the liquid in the test tube through the first tip.

Described are exemplary methods for dispensing liquid from a handheld, powered positive displacement pipette.

A method for dosing a liquid using a pipette with adjustable dosing step size and an indicating equipment and a syringe that can be operated using the pipette, wherein the syringe is detachably connected to the pipette, at option, the dosing step size is set, or the dosing step size set before is maintained, the dosing volume adjusted via the dosing step size is indicated by means of the indicating equipment, the maximum number of dosing steps possible without refilling the syringe, with the set dosing step size and completely filled syringe is indicated by means of the indicating equipment, liquid is aspirated into the syringe, a reverse stroke is performed after the syringe is filled with liquid, dosing steps are performed, the performed dosing steps are counted and the number of performed dosing steps and/or the number of dosing steps still possible without refilling the syringe is determined and indicated by means of the indicating equipment, after performing the maximum number of dosing steps possible without refilling the syringe, either the syringe is detached from the pipette, or the previous steps are performed anew by means of the same syringe, wherein in the dosing step, the overall performed number of dosing steps with the syringe with the set dosing step size is counted, and/or the number of dosing steps still possible without refilling the syringe is determined and indicated by means of the indicating equipment.

A pipette module 10 has a pipette-module frame 12 attachable to the z-axis frame 120 of a liquid handling system 100. A translatory-motion frame 14 attached to the pipette-module frame 12 is movable with respect thereto by a motor 16. A pneumatic aspirator assembly 18 including a cylinder 20, tube 24, tube tip 26 and pressure sensor 28 is attached to the translatory-motion frame 14. A piston 22 disposed in the cylinder 20 is fixedly attached to the frame 12. A controller 30 for the pipette module 10 has a liquid surface detection mode which enables a pressure feedback control algorithm causing the motor 16 to move the translatory-motion frame 14 in a z-axis translator motion until a change in a pressure in the tip 26 as sensed by the pressure sensor 28 indicates that the tip 26 has made contact with the liquid surface 110.

The invention relates to a pipette with a first opening for receiving and removing a liquid to be dispensed and a second opening which lies opposite the first opening. According to the invention, the pipette comprises a material which causes a wavelength shift between the electromagnetic radiation absorbed by the pipette and the electromagnetic radiation emitted by the pipette. The invention additionally relates to a pipette aid for receiving a pipette for dispensing a liquid. According to the invention, the pipette aid comprises both a data storage device, in which a database with reference measurement data is stored, as well as two radiation sources and a radiation detector, wherein the two radiation sources emit electromagnetic radiation with different wavelengths, and the radiation detector detects the wavelength of the received electromagnetic radiation.

A pipette with an adjustable dosing increment, a display apparatus, a drawing lever to draw liquid into a syringe, and a control button to discharge liquid in steps from the syringe, and the syringe actuated by means of the pipette, wherein the syringe is releasably connected to the pipette, the dosing increment is optionally set, or the previously set dosing increment is retained, the dosing volume set by the dosing increment is displayed by means of the display apparatus, liquid is sucked into the syringe by actuating the drawing lever, the respective position of a drive element of a drive mechanism of the pipette for filling and draining the syringe when the drive element is shifted along a path is detected, the possible maximum number of dosing steps with the set dosing increment without refilling the syringe after executing the reverse stroke starting from the position of the drive element reached at the end of filling is determined and displayed by means of the display apparatus, after the syringe is completely or partially filled with liquid, the reverse stroke is executed by actuating the control button at least once, dosing steps are executed by actuating the dosing button, the executed dosing steps are counted, the number of executed dosing steps and/or the number of still possible dosing steps without refilling the syringe are determined and displayed by means of the display apparatus, and after executing the maximum possible number of dosing steps without refilling the syringe, either the syringe is removed from the pipette, or steps 1.2 to 1.8 are repeated with same syringe, wherein in step 1.8, the total number of dosing steps performed with the syringe with the set dosing increments is counted, and/or the number of still possible dosing steps without refilling the syringe is determined and displayed by means of the display apparatus.

Devices and methods for determining whether a contact of a liquid dispenser with a liquid based on sound and/or for determining a liquid volume in the liquid dispenser are provided. According to an embodiment, the liquid dispenser includes a sound generator and an acoustic sensor, and at least one of the sound generator or the acoustic sensor is disposed within the dispense chamber portion. According to an embodiment, the liquid dispenser includes a sound generator and an acoustic sensor, and further includes one or more side conduits, where at least one of the sound generator or the acoustic sensor is disposed within a cavity of a respective one of the one or more side conduits, wherein the cavity and a connector of each of the one or more side conduits are free from resonance within a frequency range of the sound sensed by the acoustic sensor.

The present invention is directed generally to devices and methods for manipulating laboratory pipettes in a programmable manner. The present invention is directed to an apparatus and methods for allowing a user to instruct the device to perform a specific process; identifying the type, location and identity of the consumables to be used; manipulating a plurality of pipettes for performing the liquid handling; monitoring the process during and after its execution; generating a detailed report for the plurality of actions. Other aspects of this invention include optimization of the liquid dispensing performances of a pipette; monitoring and controlling individual actions by means of vision; virtualization of the protocol definition by means of a reality augmented software interface; integration of the system in a conventional laboratory environment workflow.

Techniques for antenna positioning system having a drive element shared by multiple antennas for positioning about a positioning degree of freedom are described. In some examples, each antenna can be coupled with a rotating spindle, with each antenna spindle being coupled with the shared drive element. By driving a shared drive element, each of the antenna spindles in the system can be rotated via the associated coupling. In some examples, such a coupling may include link arms with an adjustable length to reduce backlash or to apply a preload to the system. In some examples, such a coupling may be configured to position multiple antennas over different orientation ranges in response to the drive element driving over an actuation range, which may include one antenna being idled or otherwise maintained at an orientation while another antenna is driven, or may include different antennas being driven according to different actuation ratios.

The automated pipette manipulation system of the present invention allows for the automated manipulation of any pipette commercially available to aspire and dispense liquids in a chemical or biochemical laboratory setting. Measuring the amount of liquid aspired or dispensed by a pipette is conducted by a load sensor that records the starting point of the displacement of a pushbutton of said pipette and a motor that drives the displacement of said pushbutton a predetermined distance past the starting point that corresponds to a predetermined volume of liquid aspired or dispensed by said pipette. The automated pipette manipulation system of the present invention further detects whether a pipette tip is attached to said pipette and then automatically ejects said pipette tip at the end of a liquid handling process.