An auto-pipetting apparatus includes a dispensing head with at least one pipetting tip mandrel having an elongated stud body with an insertion end. The at least one pipetting tip mandrel mates with a pipetting tip. A first adjustable seal, disposed on the elongated stud body, and a second adjustable seal, disposed on the elongated stud body, seal the pipetting tip mated to the at least one pipetting tip mandrel. The first adjustable seal defines a snub surface. The snub surface effects a substantially continuous circumferential contact seal with radially impinging contact between the pipetting tip and the at least one pipetting tip mandrel. The second adjustable seal is adjustable between a disengaged position and an engaged position and effects a releasable grip and another substantially continuous circumferential contact seal between the pipetting tip and the at least one pipetting tip mandrel around the pipetting tip.

According to one embodiment, a droplet dispensing apparatus include a droplet ejecting array having a plurality of nozzles from which solution can be ejected into a microplate on a baseplate, a sensor configured to detect a solution amount in the microplate, and a controller configured to detect that a nozzle in the plurality of nozzles is malfunctioning during a solution ejection process based on an initial solution amount in the microplate and a final solution amount in the microplate as detected by the sensor, and control a supplemental droplet dispensing operation in which an additional solution amount is ejected into the microplate based on the initial solution amount and the final solution amount in the microplate.

The present disclosure provides methods and devices for sample extraction.

An add-on device for attachment to a micropipette for determining the rotational movement and longitudinal displacement of a micropipette plunger for digitization, communication and quantification of pipetting actions.

Techniques for antenna positioning system having a drive element shared by multiple antennas for positioning about a positioning degree of freedom are described. In some examples, each antenna can be coupled with a rotating spindle, with each antenna spindle being coupled with the shared drive element. By driving a shared drive element, each of the antenna spindles in the system can be rotated via the associated coupling. In some examples, such a coupling may include link arms with an adjustable length to reduce backlash or to apply a preload to the system. In some examples, such a coupling may be configured to position multiple antennas over different orientation ranges in response to the drive element driving over an actuation range, which may include one antenna being idled or otherwise maintained at an orientation while another antenna is driven, or may include different antennas being driven according to different actuation ratios.

The present invention determines whether or not a mounted tip and a dispensing amount match with each other in order to prevent contamination in a dispensing device. The present invention is provided with a pipette mechanism 108, 109 that performs suction and discharge, a motor 102 that drives the pipette mechanism, and a pressure sensor 113 that detects a pressure of the pipette mechanism. A dispensing tip 110 is mounted to the pipette mechanism. A control computer 116 controls the motor 102, drives the pipette mechanism in a suction or discharge direction, and determines a type of the dispensing tip 110 on the basis of a difference in pressure waveform detected by the pressure sensor 113.

Non-contact dispensers and related methods are disclosed. In an implementation, an apparatus includes a plate receptacle, a reagent reservoir receptacle, and a non-contact dispenser. The reagent reservoir receptacle receives a reagent reservoir containing reagent and the non-contact dispenser includes an inlet, an upstream valve, a syringe pump, a downstream valve, and an outlet. The syringe pump has a barrel and a hollow plunger movably disposed within the barrel. A flow path is defined between the inlet and the outlet and through the upstream valve, the barrel, the hollow plunger, and the downstream valve. The barrel is fluidically between the upstream valve and the downstream valve. The plate receptacle is to receive a well plate having a well and the non-contact dispenser is to dispense the reagent from the reagent reservoir into the well of the plate.

An automated pipetting system includes a pipettor. The pipettor includes a pipetting channel, a first plunger mechanism operable to change a pressure in the pipetting channel to aspirate or dispense a liquid, and a second plunger mechanism operable to change the pressure in the pipetting channel to aspirate or dispense the liquid.

An automated pipetting system includes a pipettor. The pipettor includes a pipetting channel, a first plunger mechanism operable to change a pressure in the pipetting channel to aspirate or dispense a liquid, and a second plunger mechanism operable to change the pressure in the pipetting channel to aspirate or dispense the liquid.

An automatic analyzer and a dispensing method of an reagent are provided, in which a troubleshooting time by an operator can be reduced to a shorter one than before. A control device 115 in an automatic analyzer 1: determines from a pressure value of a pressure sensor 202b whether there is an error in dispensing; determines from a capacitance value detected by a capacitance detection mechanism 117b whether a reagent dispensing nozzle, after its lowering is stopped, reaches the liquid level of a reagent; and decides a processing content for the reagent container from results of the determination on whether there is an error in the pressure and the liquid level detection determination.