B01L3/50851

Reaction processor

A reaction processor is provided with a reaction processing vessel in which a channel is formed, a liquid feeding system, a temperature control system for providing a high temperature region and a low temperature region to the channel, and a fluorescence detector for detecting the sample passing through a fluorescence detection region of the channel, and a CPU for controlling the liquid feeding system based on a signal that is detected. A target stop position X.sup.[L].sub.0(n+1) of the sample in the low temperature region in an (n+1)th cycle is corrected from a target stop position X.sup.[L].sub.0(n) of the sample in the low temperature region in the nth cycle based on the result of stopping control on the sample in the nth cycle.

DEVICE FOR HEATING OFSAMPLES
20220412853 · 2022-12-29 ·

A container for the heating of samples and a system comprising such a container and provides a container for processing samples, wherein the container is made of a material comprising electrically conductive particles.

DETECTION CHIP, METHOD OF USING DETECTION CHIP AND REACTION SYSTEM
20220410149 · 2022-12-29 ·

A detection chip, a method of using a detection chip and a reaction system are provided. The detection chip includes a first substrate, a micro-chamber definition layer and a heating electrode. The micro-chamber definition layer is located on the first substrate and defines a plurality of micro-reaction chambers. The heating electrode is located on the first substrate and closer to the first substrate than the micro-chamber definition layer, and configured to release heat after being energized. The heating electrode includes a plurality of sub-electrodes, orthographic projections of the plurality of micro-reaction chambers on the first substrate overlap with orthographic projections of at least two of the plurality of sub-electrodes on the first substrate, and the at least two of the plurality of sub-electrodes have different heating values per unit time after being energized.

MICROFLUIDIC CHIP AND MICROFLUIDIC DEVICE
20220410160 · 2022-12-29 ·

The present disclosure provides a microfluidic chip including a plurality of microcavities, at least two of the plurality of microcavities have different volumes.

Cartridge

[Problem] To ensure that a fluid is prevented from overflowing from a well and exposing the user to a biohazard. [Solution] A cartridge for use in measuring a component to be measured contained in a fluid includes a recessed well, formed for storing the fluid, the well including: a lower barrel portion that defines a lower space having a closed bottom; and an upper barrel portion that is formed above the lower barrel portion and defines an upper space having an opening on the top end, wherein a step portion is formed between the lower barrel portion and the upper barrel portion, the step portion being formed on an inner wall surface of the well and defining a step that continuously connects the inner wall surface of the lower barrel portion and the inner wall surface of the upper barrel portion.

DETECTION CHIP, METHOD FOR MANUFACTURING DETECTION CHIP, METHOD FOR OPERATING DETECTION CHIP, AND REACTION SYSTEM
20220395828 · 2022-12-15 ·

A detection chip, a method for manufacturing a detection chip, a method for operating a detection chip, and a reaction system are disclosed. The detection chip includes a first substrate, a micro-cavity definition layer, and a heating electrode. The micro-cavity definition layer defines a plurality of micro-reaction chambers. The heating electrode is configured to release heat after being energized. The heating electrode includes a first electrode portion and at least one second electrode portion. Orthographic projections of the plurality of micro-reaction chambers on the first substrate are within an orthographic projection of the first electrode portion on the first substrate, the orthographic projections of the plurality of micro-reaction chambers on the first substrate do not overlap with an orthographic projection of the second electrode portion on the first substrate, and a resistance value of the first electrode portion is greater than a resistance value of the second electrode portion.

DIGITAL PCR MEASUREMENT METHOD AND MEASUREMENT DEVICE

The purpose of the present invention is to provide a novel digital PCR analysis method. In the digital PCR analysis method disclosed herein, a method for detecting DNA is used, which includes the steps of: dividing a DNA solution containing a fluorescent-labeled probe or a DNA intercalator and a plurality of DNAs to be detected into a plurality of compartments; carrying out PCR in the compartments; measuring a fluorescence intensity in association with a change in temperature; calculating a melting temperature from a melting curve for a DNA double strand measured on the basis of a change in fluorescence intensity, which is associated with the change in temperature; and calculating a temperature difference between two points with a slope of a predetermined value on a melting curve indicating a change in the fluorescence intensity.

Tubes
20220339624 · 2022-10-27 ·

A thin-walled microplate suitable for use in the Polymerase Chain Reaction (PCR) technique comprising a plurality of thin-walled tubes or wells arranged in a fixed array, each well having an upper portion with an open top and a lower, frustoconical portion having a substantially flat bottom.

HIGHLY DEFORMABLE POROUS MEMBRANE CULTURE SYSTEM AND ACTUATION METHODS FOR STUDYING THE EFFECTS OF BIOMECHANICAL STRETCH ON CULTURED TISSUE

The systems and methods of the present disclosure provide highly deformable porous membrane culture systems and actuation methods for studying the effects of biomedical stretch on cultured tissue. A well plate can include a well having a first opening configured to receive an insert coupled to a deformable membrane. The well plate can include a gasket positioned within the well and configured to create a seal between the insert and the well when the insert is positioned in the well. The well plate can include a chamber defined beneath the well, the chamber configured to receive fluid media and to expose the fluid media to a surface of the deformable membrane when the insert is positioned in the well. The well plate can include an actuator configured to stretch the deformable membrane by a target amount of strain.

Detection chip, using method for the same, and reaction system

A detection chip, a using method for the same, and a reaction system. The detection chip includes a first substrate, a micro-cavity defining layer, and a heating electrode. The micro-cavity defining layer is on the first substrate and defines a plurality of micro-reaction chambers. The heating electrode is on the first substrate and is closer to the first substrate than the micro-cavity defining layer, and is configured to heat a plurality of micro-reaction chambers. The orthographic projection of the plurality of micro-reaction chambers on the first substrate is within the orthographic projection of the heating electrode on the first substrate.