B01L3/50857

Roughly cylindrical sample containers having multiple reservoirs therein and being adapted for acoustic ejections
11731133 · 2023-08-22 · ·

Provided herein is generally tubular container, preferably including a plurality of reservoirs defined therein. The container can be adapted for acoustic ejection of a fluid disposed within at least one of the reservoirs of the plurality of reservoirs. Alternatively, the container can be adapted for extraction of a fluid disposed within at least one of the reservoirs of the plurality of reservoirs using a non-acoustic liquid handling method.

SAMPLE STORAGE DEVICE
20220017304 · 2022-01-20 ·

A sample storage device may include: a storage chamber; paired rail sections separated in separating direction and extending in an extending direction; an antenna array substrate extending between the rail sections and having antennas; paired slide sections separated from each other in the separating direction and disposed at a position opposite to the antenna array substrate with respect to the rail sections and, so as to be slidable in the extending direction relative to the rail sections, respectively; a support plate transparent to radio waves, extending between the slide sections; and a storage box containable a plurality of containers each holding a sample and a radio tag, the storage box to be set on the support plate such that radio waves can be transmitted between the radio tag and corresponding one of the plurality of antennas.

Device with integrated methods for reverse transcription polymerase chain reaction (RT-PCR) and/or DNA/protein array based analyses

A device with integrated methods for carrying out reverse transcription polymerase chain reaction (RT-PCR) and/or array based analysis involving signal generating agents (gold nanoclusters) comprising a heating and cooling cycle based synthesis selectively with DIMA and protein as templates. The advancement is further directed to a portable device adapted for RT-PCR and array based gene and protein expression analyses based on a common detection agent involving luminescence of in-situ synthesized gold nanoclusters with adaptability for user friendly graphical user interface (GUI) for controlling, visualization and analysis of the data.

METHODS, TOOLS, AND TOOL ASSEMBLIES FOR BIOMOLECULAR ANALYSIS USING MICROARRAYS

Disclosed herein are methods, tools, pillar plates, and tool assemblies for biomolecular analysis using microarrays that reduces the likelihood of air bubbles being trapped by the microarrays. Embodiments of the tools include two clamps that have a tool mount portion and a grasping portion. The tool mount portion is configured to engage a lifting mechanism of a plate handling robot for moving a pillar plate that include microarrays. The grasping portion is configured to freely suspend the pillar plate at an inclination of a non-zero tilt angle relative to a plane normal to the tool mount portion. Embodiments of pillar plates include two protruding edges on opposite sides of the pillar plate and a plurality of pillars with one or more affixed microarrays. Embodiments of the tool assembly include the tool and the pillar plate, wherein the protruding edges are configured to engage with the grasping portions.

Biologic sample preparation system and related method

A biologic sample preparation system that prepares samples for processing includes a frame defining a horizontal plane, a pipette assembly, a sample module and an extraction module. The pipette assembly includes a first pipette. The pipette assembly is movably mounted to the frame in a direction substantially perpendicular to the horizontal plane during operation. The sample module includes a sample plate and is movably mounted to the frame. The sample module is movable substantially parallel to the horizontal plane at least from a sample area spaced from the pipette assembly and a working area proximate the pipette assembly. The extraction module includes an extraction plate and is movably mounted to the frame. The extraction module is movable substantially parallel to the horizontal plane at least from an extraction staging area spaced from the pipette, assembly and the working area proximate the pipette assembly.

ULTRAFAST PARTICLE SORTING

Described are platforms, systems, media, and methods for maintaining a database of items associated with one or more skill requirements and a visit duration; maintaining a database of experts associated with one or more skill proficiencies, a location, and a schedule; receiving a request from a consumer for delivery by an expert of one or more items in the database to a consumer address; identifying experts in the database having skill proficiencies matching the skill requirements of the one or more items and available in a timeslot for the visit duration of the one or more items; presenting timeslots for which one or more experts are identified to the consumer and allowing the consumer to select a timeslot; and selecting an expert from among the identified experts in the selected timeslot based on shortest travel time; provided that utilization of the selected expert exceeds a predetermined utilization threshold.

Simultaneous spot test and storage of blood samples
11772097 · 2023-10-03 · ·

A blood sample collection and/or storage device includes a two-piece housing that encompasses a port at which a fingertip blood sample is collected. After the sample is taken, the two-piece housing is moved to a closed position to protect the sample for storage and optionally process the sample within the housing. The housing may also be opened to access the stored sample for further processing.

Sample support body

Provided is a sample support body that includes a substrate, an ionization substrate, and a support. The ionization substrate has a plurality of measurement regions for dropping a sample on a second surface. A plurality of through-holes that open in a first surface and the second surface are formed at least in the measurement regions of the ionization substrate. A conductive layer is provided on peripheral edges of the through-holes at least on the second surface. The support has a first support provided on peripheral edges of the measurement regions on the first surface to separate the plurality of measurement regions when viewed in the direction in which the substrate and the ionization substrate face each other.

LIQUID SUPPLY METHOD
20230144260 · 2023-05-11 ·

The method includes preparing a liquid supply pipe in which the solution to be inspected, air, and oil are disposed in this order, and installing the liquid supply pipe above the substrate at an angle such that the solution to be inspected is positioned on a lowermost side and the solution to be inspected, the air, and the oil flow onto a front surface of the substrate by gravity. A cross-sectional area of the liquid supply pipe is designed such that the air continues to be present between the solution to be inspected and the oil while the solution to be inspected, the air, and the oil are flowing through the liquid supply pipe, and after the solution to be inspected is supplied to the spot, the solution to be inspected present on the front surface of the substrate is replaced with the air, and then the liquid supply progresses.

Micro-fabricated multi-well chips for long term automated imaging of <i>C. elegans </i>growth and behavior

A composition, including a substrate having a planar array of depressions each defined by concave walls and a moat disposed around each depression of said array of depressions.