The present invention provides means and methods for delivering a predetermined volume of a substance, within at least one body cavity of a subject, comprising a predefined volume for containing the predetermined volume of the at least one substance; a delivery end for placement in proximity to the body cavity; the delivery end comprises at least one orifice of diameter D [mm]; a valve mechanically connectable to the container, characterized by at least two configurations: (i) an ACTIVE CONFIGURATION in which the valve enables delivery of predetermined volume V.sub.sub [ml] of the substance; and, (ii) an INACTIVE CONFIGURATION, in which the valve prevents delivery of the predetermined volume V.sub.sub [ml] of the substance from the container to the body cavity; and a fluid tight chamber configured to contain predetermined volume V.sub.gas [ml] of pressurized gas at a predetermined pressure, P.sub.gas [barg].

A nebulizer for nebulizing a fluid and a reservoir with a fluid are proposed. The reservoir includes a collapsible bag with the fluid, where the bag extends in a circumferential direction within the housing part and wherein the reservoir is manually rotated for tensioning the nebulizer.

A nebulizer includes a replaceable container with fluid to be nebulized. The container includes an inseparable indicator device. The container and the indicator device are axially moved during nebulization and tensioning of the nebulizer. The indicator device controls locking of the nebulizer against further use if a predetermined number of uses has been reached or exceeded.

A nebulizer for nebulizing a liquid from a container includes a fluid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The nebulizer includes in addition an air pump with a piston/cylinder arrangement for pumping air into the container to pressurize the liquid in the container to help withdrawing the liquid from the container.

The present invention provides a device for delivering a predetermined volume of a substance, within at least one body cavity of a subject, comprising a predefined volume for containing the predetermined volume of the at least one substance; a delivery end for placement in proximity to the body cavity; the delivery end comprises at least one orifice of diameter D [mm]; a valve mechanically connectable to the container, characterized by at least two configurations: (i) an active configuration in which the valve enables delivery of predetermined amount M.sub.sub of the substance; and, (ii) an inactive configuration, in which the valve prevents delivery of the predetermined amount M.sub.sub of the substance from the container to the body cavity; and a fluid tight chamber configured to contain predetermined volume V.sub.gas of pressurized gas at a predetermined pressure, P.sub.gas.

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an inhalation device having improved flow characteristics. A inhalation device for medically active liquids (F) for generation of an aerosol comprises a housing (1), inside this housing (1) a reservoir (2) for storing a liquid (F), a pumping device with a hollow cylinder (9) providing a pumping chamber (3) for the generation of a pressure inside said pumping chamber (3), wherein the pumping chamber is fluidically connected with the reservoir (2) via an inlet check valve (4) which blocks in direction of the reservoir (2), a riser pipe (5) which can be received with at least one reservoir-facing, interior end (5A) in said hollow cylinder (9), and a nozzle (6) which is connected liquid-tight to an exterior end (5B) of the riser pipe (5), wherein the volume of the pumping chamber (3) is changeable by means of relative motion of the cylinder (9) to the riser pipe (5), and is characterised in that the riser pipe (5) is immobile and firmly attached to the housing (1) and to the nozzle (6), whereas the hollow cylinder (9) is moveable relative to the housing (1) and to the nozzle (6). The invention also discloses a method for the generation of an aerosol of a medically active liquid (F) by means of an inhalation device.

A nebulizer for nebulizing a liquid from a container, where the nebulizer includes a fluid pump for withdrawing the liquid in doses from the container and pressurizing the respective doses for nebulization. The container includes an air pump with a piston/cylinder arrangement to pressurizing the liquid in the container to help withdrawing the liquid from the container. A control valve limits the air pressure acting on the liquid.

A nebulizer for nebulizing a fluid from a cartridge and a cartridge for such a nebulizer is proposed. The cartridge comprises a container containing the fluid to be nebulized and is fluidically connected to the nebulizer by inserting a connecting element of the nebulizer for conveying the fluid out of the container. The cartridge is preferably adapted to sealingly receive the connecting element and can optionally comprise a membrane or sealing wall which seals the cartridge initially and is piercable or breakable by the connecting element upon insertion. The cartridge can further comprise an at least partially flexible and/or bendable tube for conveying the fluid out of the container. The tube is preferably wettable with the fluid and/or comprises an at least partially hydrophilic and/or polar surface. Further, the tube can at least partially be shaped as a helix. When the cartridge is connected to the nebulizer, the tube and the connecting element preferably form a continuous capillary and/or an at least essentially constant flow area.

The present invention relates to a device for the delivery of a mist of a dose of an ophthalmic liquid, including a housing with a holding chamber having a discharge opening for holding the dose of liquid to be delivered, a pump for pumping, via a dose supply conduit, the dose of the liquid to the holding chamber, the pump being connected with a container containing a plurality of the doses, and an air flow conduit for supplying a flow of air to the holding chamber so as to force the dose delivered by the pump to the holding chamber out through the discharge opening.

An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.