A human milk powderization system can include a spray drying machine, a receptacle, and a container. The spray drying machine can be configured to receive liquid human milk through an inlet at a rate of about 2 milliliters per minute and to spray dry the human milk at a temperature of about 163 to 167 degrees C. to transform the liquid human milk into a powderized human milk product. The receptacle can be coupled to and configured to receive the powderized human milk product from the spray drying machine. The receptacle can be formed from one or more nonreactive materials, such as crystal. The container can be removably coupled to and configured to receive the powderized human milk product from the receptacle. The container can be configured to transport the powderized human milk product away from the system, and can be formed from one or more nonreactive materials, such as aluminum.

A time and possibly a temperature device connects to a container with a band extending circumferentially around a portion of the container. The device has an input, a processor and a display permitting a countdown timer to be initiated relating to a status of goods in the container. For some embodiments, if temperature exceeds set ranges for specific times, step reductions, such as 10% or more can be deducted from the remaining time. The display can provide an indication of the status of the material in the container, and some embodiments provide for remote alerting to a remote communications device, such as a phone.

The disclosure features human milk compositions as well as methods of making human milk compositions and using human milk compositions. In particular, the disclosure features a method of using milk compositions to provide nutrition for subjects who are undergoing or have undergone bone marrow transplants.

A device for obtaining protein-enriched fractions from human or animal milk comprises a delipidating unit for reducing a lipid content in the human or animal milk to obtain delipidated milk and a filtering unit for increasing a protein concentration of the delipidated milk to obtain the protein-enriched fraction, comprising a replaceable filter having a nominal molecular weight limit of 2 kDa or more, in particular of 5 kDa or more.

This disclosure features human milk permeates and compositions containing the same obtained from fractionated whole human milk. The oligosaccharide rich permeate and permeate compositions of the present invention are useful as nutritional supplements for pre-term and full term infants, for establishing or maintaining gut flora and for treating the symptoms of inflammatory bowel disease.

A pasteurization device comprising an insulated heating tub, a metal grid heat sink, 69 C. melt-point paraffin wax, wherein the metal grid heat sink and the paraffin wax are combined inside the insulated heating tub; a temperature sensor connected to a microprocessor controlled device, suitable to measure temperature and to generate an alarm, a top plate, and a material suitable to cover the wax; wherein the top plate comprises a plurality of openings corresponding to an opening in the metal grid heat sink of suitable size to accept a baby bottle; wherein the insulated heating tub can be heated to at least 73 C. and wherein the microprocessor controlled device provides an audible tone upon the temperature sensor reading 73 C. for at least 30 seconds.

Systems and methods for generating a sterilized human milk product from raw human milk, and sterilized human milk product compositions obtained thereby, are provided. The method includes sterilizing the milk using a countercurrent heating process. The temperature of the milk is raised to a target temperature for a duration of time that is refined to provide a sterilized human milk product with low overall bioburden while also maintaining nutritional quality. As such, the sterilized milk product is suitable for ingestion by premature infants.

A process for preparing a low-lactose or lactose free mammalian milk product comprises the steps of enzymatically hydrolysing the lactose present in mammalian milk, diluting the milk with a lactose-reduced liquid, and adding one or more of a protein, a mineral, a vitamin, a gum, a starch, a stabiliser, and/or an emulsifier to the milk.

The present invention relates to a method for treating raw human milk to produce treated human milk having undetectable levels of bacteria. The milk is skimmed to produce skim human milk then subjected to microfiltration to yield a filtrate which has undetectable levels of bacteria, including Bacillus cereus. The resultant human milk can be further processed, used and/or sold.

The invention relates to the Proline-Rich Polypeptide complex (PRP) derived from the mammalian colostrum for use in the treatment of the disorders and conditions related to the alterations of the Brain-Derived Neurotrophic Factor level as well as modulation thereof, particularly disorders and conditions wherein therapeutic strategy is based on the increasing of the BDNF concentration in blood.

The PRP complex is postulated to be used for nutrition of adults, young children/babies and infants to promote and preserve the proper development and function of both immune and nervous system. PRPs may be used for supplementation of modified milk and infant milk formulae to make it closer to breast milk.