A continuous and fully-automatic energy-saving production line and method for vacuum glass are provided. The production line includes conveying roller tables that run through the entire production line, and includes a feeding platform, a low-vacuum pumping chamber, a high-vacuum pumping chamber, a main processing chamber, a high-vacuum automatic cooling chamber, a first-stage boosting and automatic cooling chamber, and a second-stage boosting and automatic cooling chamber in sequence. The main processing chamber is integrally welded, and cylindrical in shape, with two sides respectively provided with inspection holes; the low-vacuum pumping chamber and the high-vacuum pumping chamber are connected to form a degassing section; the high-vacuum automatic cooling chamber, the first-stage boosting and automatic cooling chamber, and the second-stage boosting and automatic cooling chamber form a cooling section; and the degassing section and the cooling section are respectively connected to two ends of the main processing chamber through sealing doors.