An accessory device for delivering medications from press and breath metered-dose inhalers (pMDIs), including those medications containing hydrofluoroalkane propellants. The device includes a collapsible flexible bag to which is attached a bidirectional mouthpiece and an adaptor that receives the press and breath MDI. The mouthpiece contains a reed that functions as an audible signal, and a screen to prevent inhalation of unwanted particles. The adaptor positions the press and breath MDI at an angle to direct the aerosol spray toward the center of the collapsible flexible bag. When the press and breath MDI is triggered, it discharges the aerosolized medication into the center of the collapsible flexible bag which is then inhaled by the user through the mouthpiece. This collapses the bag. The reed emits an audible sound if the user inhales above a pre-determined flow rate to maximize medication delivery and ensure dose-to-dose consistency.

A metering valve includes: a high-pressure partition wall to isolate a storage region from an atmospheric pressure space; an internal partition wall arranged inside the high-pressure partition wall and forming a metering chamber partitioned from the storage region; a stem linearly movably supported and biased to be positioned at an origin position; a first seal hole penetrating the high-pressure partition wall to extend over the atmospheric pressure space and the metering chamber with a first seal portion linearly movably supporting a first intermediate portion; a second seal hole penetrating the internal partition wall to extend over the metering chamber and the storage region with a second seal portion linearly movably supporting a second intermediate portion; and a starting-end-side stem internal flow path formed inside the stem and extending from a starting end of the stem to the second intermediate portion, the starting end being always positioned in the storage region.

A discharge apparatus and a discharge method for a moving vehicle are provided in which a content in an aerosol container can be stirred in a state where the aerosol container is mounted on the moving vehicle, so that the content of a constant quality can be discharged. The discharge apparatus for a moving vehicle, which is provided with an aerosol container mounted on the moving vehicle and discharges the content in the aerosol container, is characterized by including a stirring means that stirs the content by causing the aerosol container to rotate, reciprocate, swing, vibrate, or otherwise move with respect to the moving vehicle.

Aerosol actuation mechanisms include improvements allowing a user to extend the reach of an aerosol application device, apply an aerosol in a windy environment, improve coverage of the aerosol product, or facilitate improved ability to ensure coverage for an aerosol product.

A nasal inhaler for the inhalation of inhalable substances comprise: a canister having an interior reservoir containing pressurised inhalable substances including fluid; a metering valve including a metering chamber and a valve stem defining a communication path between the metering chamber and the interior reservoir, the communication path including an opening configured to permit flow between a transfer space inside the valve stem and the interior reservoir, the interior reservoir being arranged for orientation above the metering chamber whereby gas located within the metering chamber is replaced with liquid from the interior reservoir.

A refill assembly (129) for use in a medicinal inhaler (100). The refill assembly includes a patient port (110), and an adapter (118) configured to cause a dose of medicament to be released. The adapter is movable between a first position in which a dose of medicament is not released and a second position in which a dose of medicament is released. The refill assembly further includes a lockout member (117) movable between (i) a first (locked) position in which the adapter is not movable from its first position to its second position, and (ii) a second (unlocked) position in which the adapter is movable from its first position to its second position.

A metering valve includes: a high-pressure partition wall to isolate a storage region from an atmospheric pressure space; an internal partition wall arranged inside the high-pressure partition wall and forming a metering chamber partitioned from the storage region; a stem linearly movably supported and biased to be positioned at an origin position; a first seal hole penetrating the high-pressure partition wall to extend over the atmospheric pressure space and the metering chamber with a first seal portion linearly movably supporting a first intermediate portion; a second seal hole penetrating the internal partition wall to extend over the metering chamber and the storage region with a second seal portion linearly movably supporting a second intermediate portion; and a starting-end-side stem internal flow path formed inside the stem and extending from a starting end of the stem to the second intermediate portion, the starting end being always positioned in the storage region.

An auto-reset dose release firing system (101) and a method of using same. The system can include an a stored energy device (109); a first plunger (103) movable between first, second, and third positions, the first plunger configured to be operatively coupled to a medicament canister (51); and a second plunger (104) movable between first and second positions; the first and second plunger being movable with respect to one another and shaped to define an evacuable chamber (185) therebetween. The first plunger and the second plunger can move together from their respective first positions to their respective second positions, due to a reduced pressure in the chamber, to cause a dose release valve (54) to fire. After firing, air can be allowed to move into the chamber to allow the first plunger to move with respect to the second plunger to its third position to allow the dose release valve to reset.

An inhaler (10) for the inhalation of inhalable substances comprise: a canister (50) having an interior reservoir (84) containing pressurised inhalable substances including fluid; a metering valve (52) including a metering chamber (82) and a valve stem (54) defining a communication path between the metering chamber and the interior reservoir, the communication path (86) including an opening (106) configured to permit flow between a transfer space inside the valve stem and the interior reservoir, the interior reservoir being arranged for orientation above the metering chamber whereby gas such as air located within the metering chamber is replaced with liquid from the interior reservoir.

The present disclosure relates to a dispenser. Specifically, the dispenser comprises a housing and a stop member fixedly positioned in the housing configured to receive at least a portion of a container and an actuator engagable by a user, whereby contents of the container are released.