The present invention provides an aerosol device for delivering a pharmaceutical formulation by inhalation via the mouth to the lungs or to the nostril in metered doses comprising: a pressurised aerosol canister including a vial containing a pharmaceutical formulation comprising an active ingredient, a propellant and, optionally, a co-solvent, the aerosol canister further comprising a metering valve having a valve stem; and an actuator for the aerosol canister, the actuator including a delivery outlet and a stem block, the stem block having a receptacle into which the valve stem of the metering valve of the aerosol canister is received and axially located and being displaceable relative to the vial of the aerosol canister to actuate the metering valve of the aerosol canister, a sump extending below the receptacle, the stem block further defining a discharge orifice arranged to direct the pharmaceutical formulation through the delivery outlet, a transfer tunnel having an input opening and an output opening through which a dispensed dose of the pharmaceutical formulation is able to pass from the sump to the discharge orifice, and a land length defining the distance from between the input opening and output opening, wherein the input opening and the output opening have cross-sectional areas of from 0.002 to 0.8 mm.sup.2 and the cross-sectional area of the input opening is smaller than the cross-sectional area of the output opening, and wherein the land length is from 0.5 mm to 10 mm.

A ring for arranging around a valve body of a fluid dispenser valve mounted by a fastener capsule on a reservoir containing fluid to be dispensed. The ring includes a single piece including at least one inner portion that co-operates with the valve body, a radial flange that forms a neck gasket between the neck of the reservoir and the fastener capsule, and at least one axial recess that extends, at least in part, around the periphery of the ring, radially inwards from the radial flange, the single piece is made out of a first material that is substantially deformable; and at insert least one filler insert that fills the at least one axial recess at least in part, the at least one filler made out of a second material that is more rigid than the first material, the at least one filler insert being over-molded on the single piece.

A ring for arranging around a valve body of a fluid dispenser valve mounted by a fastener capsule on a reservoir containing fluid to be dispensed. The ring includes a single piece including at least one inner portion that co-operates with the valve body, a radial flange that forms a neck gasket between the neck of the reservoir and the fastener capsule, and at least one axial recess that extends, at least in part, around the periphery of the ring, radially inwards from the radial flange, the single piece is made out of a first material that is substantially deformable; and at insert least one filler insert that fills the at least one axial recess at least in part, the at least one filler made out of a second material that is more rigid than the first material, the at least one filler insert being over-molded on the single piece.

A fluid dispenser device having at least one reservoir (20) that is suitable for containing fluid to be dispensed; a pump (1) that is mounted on the reservoir (20); and a dispenser head (2) including a dispenser orifice (3) via which the fluid is dispensed, which dispenser head is suitable for actuating said pump (1). At least a rigid and/or non-deformable portion of the dispenser device is made out of a material comprising an aliphatic polyketone.

A fluid dispenser device having at least one reservoir (20) that is suitable for containing fluid to be dispensed; a pump (1) that is mounted on the reservoir (20); and a dispenser head (2) including a dispenser orifice (3) via which the fluid is dispensed, which dispenser head is suitable for actuating said pump (1). At least a rigid and/or non-deformable portion of the dispenser device is made out of a material comprising an aliphatic polyketone.

A method and a system are described herein for preparing a custom cosmetic formulation. The system includes a controller in electronic communication with an order management system, wherein the order management system stores user-specific data including data related to a custom cosmetic formulation and components thereof, a plurality of valves for receiving pressurized fluid, the plurality of valves in electronic communication with the controller; a plurality of dispensers, each having a valve for metering fluid in predetermined quantities, and each having a dispensing head having a nozzle, each nozzle comprising a nozzle tip on a distal end thereof, wherein the nozzle tips are arranged so as to dispense a fluid into an inlet of a product receptacle, the dispensers in electronic communication with a data port; a measuring device in electronic communication with the controller, the measuring device capable of capturing data related to dispensed fluids from each of the plurality of dispensers and transmitting the data to the controller; a barcode scanner for reading order-specific instructions; a user interface for operator communication with the order management system and with the controller; a plurality of fluid conduits for introducing fluid to the dispensers; a fluid delivery apparatus for delivery of components of a custom cosmetic component to the dispensers; and a pressure source for pressurizing fluid in the fluid delivery apparatus for delivery of fluid from the fluid delivery apparatus to the plurality of dispensers.

A method and a system are described herein for preparing a custom cosmetic formulation. The system includes a controller in electronic communication with an order management system, wherein the order management system stores user-specific data including data related to a custom cosmetic formulation and components thereof, a plurality of valves for receiving pressurized fluid, the plurality of valves in electronic communication with the controller; a plurality of dispensers, each having a valve for metering fluid in predetermined quantities, and each having a dispensing head having a nozzle, each nozzle comprising a nozzle tip on a distal end thereof, wherein the nozzle tips are arranged so as to dispense a fluid into an inlet of a product receptacle, the dispensers in electronic communication with a data port; a measuring device in electronic communication with the controller, the measuring device capable of capturing data related to dispensed fluids from each of the plurality of dispensers and transmitting the data to the controller; a barcode scanner for reading order-specific instructions; a user interface for operator communication with the order management system and with the controller; a plurality of fluid conduits for introducing fluid to the dispensers; a fluid delivery apparatus for delivery of components of a custom cosmetic component to the dispensers; and a pressure source for pressurizing fluid in the fluid delivery apparatus for delivery of fluid from the fluid delivery apparatus to the plurality of dispensers.

The purpose of the present invention is to enable a metering chamber and a propellant-accommodating space region to be reliably isolated from each other at a metering valve mechanism, where contents placed in an inner bag is discharged from the metering chamber to the outside space by means of an annular piston which is moved by pressure from the propellant acting thereon and is for configuring the metering chamber, the isolation being achieved by preventing the contents loaded into the inner bag from leaking through both inner and outer edges of a contents-receiving surface section of the annular piston to a propellant-receiving surface side on the other side thereof. For example, an annular piston 8 of a bag-on-valve type metering valve mechanism is composed of a lower surface section for having act thereon the pressure from contents to be sprayed, which are loaded via a stem vertical center passage section 6a and an inner housing 3 (3a+3b), and an upper surface section disposed on the other side thereof and having act thereon the pressure from a propellant via an upper vertical hole part 4f. An inner lower-side inverted skirt-like section 8b for providing a seal with the outer peripheral surface of the inner housing 3 and an outer lower-side skirt-like section 8b for providing a seal with the inner peripheral surface of an outer housing 4 are formed at least at the edges of the lower surface section.

The purpose of the present invention is to enable a metering chamber and a propellant-accommodating space region to be reliably isolated from each other at a metering valve mechanism, where contents placed in an inner bag is discharged from the metering chamber to the outside space by means of an annular piston which is moved by pressure from the propellant acting thereon and is for configuring the metering chamber, the isolation being achieved by preventing the contents loaded into the inner bag from leaking through both inner and outer edges of a contents-receiving surface section of the annular piston to a propellant-receiving surface side on the other side thereof. For example, an annular piston 8 of a bag-on-valve type metering valve mechanism is composed of a lower surface section for having act thereon the pressure from contents to be sprayed, which are loaded via a stem vertical center passage section 6a and an inner housing 3 (3a+3b), and an upper surface section disposed on the other side thereof and having act thereon the pressure from a propellant via an upper vertical hole part 4f. An inner lower-side inverted skirt-like section 8b for providing a seal with the outer peripheral surface of the inner housing 3 and an outer lower-side skirt-like section 8b for providing a seal with the inner peripheral surface of an outer housing 4 are formed at least at the edges of the lower surface section.

A piston for centrifugation according to one embodiment may include: a body; a valve which can move inside the body to the front side and the rear side of the body according to an applied external force; a fluid channel through which a fluid flows from the front side of the body to the rear side of the body; and a valve support for guiding movement of the valve.