This invention relates to the use of the combination of 25-hydroxyvitamin D3 (25-OH D3) and antioxidants/anti-inflammatories (ascorbic acid, vitamin E and at least one carotenoid) to make a pharmaceutical, nutraceutical or food supplement which can ameliorate various problems observed in humans connected with polycystic ovarian syndrome and cardiovascular diseases. Pharmaceuticals, nutraceuticals and food supplements containing the 25-OH D3 and antioxidants/anti-inflammatories and premixes are also provided.

This invention relates to the use of the combination of 25-hydroxyvitamin D3 (25-OH D3) and antioxidants/anti-inflammatories (ascorbic acid, vitamin E and at least one carotenoid) to make a pharmaceutical, nutraceutical or food supplement which can ameliorate various problems observed in humans connected with polycystic ovarian syndrome and cardiovascular diseases. Pharmaceuticals, nutraceuticals and food supplements containing the 25-OH D3 and antioxidants/anti-inflammatories and premixes are also provided.

The invention pertains to a method for synthesizing a product of interest by culturing a microalgal cell obtained from a subterranean habitat for producing the product of interest. The microalgal cell obtained from a subterranean habitat can be cultured in the dark, in light, in low nutrition, or nutrient rich conditions for at least a portion of production cycle. A combination of these conditions can be used to specifically manipulate a microalgal cell culture to produce a product of interest. The product of interest can be a water-soluble carotenoid, for example, a water-soluble carotenoid produced by culturing an algae belonging to the genus Haematococcus or a capsular exopolysaccharide produced by culturing an algae belonging to the genus Parachlorella. Compositions containing the water-soluble carotenoid, for example, as sunscreen and compositions containing the exopolysaccharide, for example, as moisturizing cream are also described.

The present invention relates to a new alga having an improved ability to produce a pigment, and when a mutant of the present invention is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. Further, the pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. In particular, since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO, so that it is expected that the procedure of constructing the mutant can create a big economic effect in terms of an industry which produces lutein and zeaxanthin by using microalgae.

The present invention relates to a new alga having an improved ability to produce a pigment, and when a mutant of the present invention is used, a carotenoid-based pigment, specifically, a xanthophyll can be produced by consuming less energy, so that it is possible to efficiently produce the pigment at the industrial level. Further, the pigment can be applied as a raw material for a food, a health functional food and a medicine, which include the pigment. In particular, since a DNA fragment is not likely to be inserted into a target base sequence or a base sequence other than the target, it is expected that the procedure of constructing the mutant is not regulated as a GMO, so that it is expected that the procedure of constructing the mutant can create a big economic effect in terms of an industry which produces lutein and zeaxanthin by using microalgae.

The present invention relates to the use of bacterial 3-phytases for the production of feed or food products. Further, the present invention relates to the use of bacterial 3-phytases for feeding animals and for the production of a food or feed additive.

The present invention relates to the use of bacterial 3-phytases for the production of feed or food products. Further, the present invention relates to the use of bacterial 3-phytases for feeding animals and for the production of a food or feed additive.

The present invention provides a composition comprising a high content of highly pure, low-cost, and safe carotenoid and a method for industrially producing the same. The present invention also provides functional food, a pharmaceutical composition and a cosmetic product comprising such a composition. The present invention further provides a method for producing a composition containing at least 80% of carotenoid, which is characterized in treating a microorganism culture with extraction using a lower alcohol at 80 C. at the lowest or a combination of water and a lower alcohol at 80 C. at the lowest, and then washing and filtrating the precipitate obtained from the extract solution with a combination of a lower alcohol and water.

The present invention provides a composition comprising a high content of highly pure, low-cost, and safe carotenoid and a method for industrially producing the same. The present invention also provides functional food, a pharmaceutical composition and a cosmetic product comprising such a composition. The present invention further provides a method for producing a composition containing at least 80% of carotenoid, which is characterized in treating a microorganism culture with extraction using a lower alcohol at 80 C. at the lowest or a combination of water and a lower alcohol at 80 C. at the lowest, and then washing and filtrating the precipitate obtained from the extract solution with a combination of a lower alcohol and water.

A comprehensive nutrition pet food that satisfies a nutritional food standard for a dog or a cat, the comprehensive nutrition pet including a unicellular organism ingredient containing astaxanthin and being free of meals, in which a content of the astaxanthin is 0.0012% to 0.0080% by mass, relative to a total amount of the comprehensive nutrition pet food, and an a* value of the comprehensive nutrition pet food in an L*a*b* color space is 8.0 to 20.