Systems and methods for protecting autonomous mobile machine tailgating may include an elevator control system that receives, from an autonomous mobile machine, an request signal requesting access by the autonomous mobile machine to a restricted floor of a facility. The elevator control system may also determine a presence of an individual in an elevator with the autonomous mobile machine. The elevator control system may perform a tailgate prevention operation to prevent an unauthorized access of the individual to the restricted floor by following the autonomous mobile machine. The elevator control system may also provide access for the autonomous mobile machine to exit the elevator at the restricted floor, in response to the tailgate prevention operation being performed.