B01F25/4332

FLOW CELL FOR THE SELECTIVE ENRICHMENT OF TARGET PARTICLES OR CELLS
20200164376 · 2020-05-28 ·

The present invention relates to the field of micro fluidics. Specifically, the present invention relates to a novel flow cell for the selective enrichment of target particles or cells from a fluid. The flow cell exhibits a novel design which greatly improves the target particle or cell yield. The invention also provides a micro fluidic device, comprising the flow cell according to the invention. In another aspect, the invention relates to the use of a flow cell or a micro fluidic device of the invention for the isolation of target particles or cells from a fluid sample. Finally, the invention relates to a method for the selective enrichment of target particles or cells from a fluid using the flow cell of the invention.

High performance static mixer

A static mixer device comprising a housing having a proximal end, a distal end, and an opening extending between the proximal and distal ends. In certain embodiments, a plurality of metal frits is positioned within the opening of the housing, each of the metal frits extending across a cross-sectional dimension of the opening and having interconnected porosity. In other embodiments, one or more mixer elements fabricated using laser additive manufacturing technology and having novel configurations are positioned within the opening of the housing. In yet other embodiments, the housing comprises multiple openings having different diameters from each other, with each opening either extending through the housing with a constant diameter or with one or more of the openings having a varying diameter.

Exhaust gas post-treatment apparatus

An exhaust gas post-treatment apparatus comprises a first mixing chamber assembly and a second mixing chamber assembly. The first mixing chamber assembly comprises a first housing provided with a first mixing chamber, a gas inlet pipe, a first mixing pipe at least partially located in the first mixing chamber and a perforated pipe located in the first mixing pipe. The first mixing pipe includes a first pipe body located in the first mixing chamber and a second pipe body extending from the first mixing chamber, wherein a side wall of the first pipe body is provided with apertures and flow plates located in the first mixing chamber. In the axial direction of the perforated pipe, the perforated area of the perforated pipe fully covers the length of the flow plates. The second mixing chamber assembly includes a flow-guiding hood.

Interaction chambers with reduced cavitation

Apparatuses and methods that reduce cavitation in interaction chambers are described herein. In an embodiment, an interaction chamber for a fluid processor or fluid homogenizer includes an inlet chamber having an inlet hole and a bottom end, an outlet chamber having an outlet hole and a top end, a microchannel placing the inlet hole in fluid communication with the outlet hole, wherein an entrance to the microchannel from the inlet chamber is offset a distance from the bottom end, and at least one of: (i) a tapered fillet located on a side wall of the microchannel at the microchannel entrance; (ii) a side wall of the microchannel converging inwardly from the inlet chamber to the outlet chamber; (iii) a top wall and/or bottom wall of the microchannel angled from the inlet chamber to the outlet chamber; and (iv) a top fillet that extends around a diameter of inlet chamber.

EXHAUST GAS POST-TREATMENT APPARATUS

An exhaust gas post-treatment apparatus comprises a first mixing chamber assembly and a second mixing chamber assembly. The first mixing chamber assembly comprises a first housing provided with a first mixing chamber, a gas inlet pipe, a first mixing pipe at least partially located in the first mixing chamber and a perforated pipe located in the first mixing pipe. The first mixing pipe includes a first pipe body located in the first mixing chamber and a second pipe body extending from the first mixing chamber, wherein a side wall of the first pipe body is provided with apertures and flow plates located in the first mixing chamber. In the axial direction of the perforated pipe, the perforated area of the perforated pipe fully covers the length of the flow plates. The second mixing chamber assembly includes a flow-guiding hood.

Chemical treatment apparatus for diluting and activating polymers and methods thereof
10526481 · 2020-01-07 · ·

A chemical treatment apparatus for diluting and activating a polymeric material can include a mixing chamber having a first end, a second end, a first baffle plate positioned between the first end and second end, a high shear mixing zone positioned between the first end of the mixing chamber and the first baffle plate, and a low shear mixing zone positioned downstream from the high shear agitation zone between the second end of the mixing chamber and the first baffle plate. The volume ratio of the high shear mixing zone to the low shear mixing zone can be in the range of 1:2 to 1:10. A method and system for diluting and activating polymeric materials are also disclosed.

METHOD AND DEVICE FOR PREPARING MODIFIED POLY (M-PHENYLENE ISOPHTHALAMIDE) (PMIA) FIBER BY CONTINUOUS POLYMERIZATION-DRY-WET SPINNING

The present disclosure provides a method and a device for preparing a modified poly (m-phenylene isophthalamide) (PMIA) fiber by continuous polymerization-dry-wet spinning. The method includes the following steps: (1) preparing a mixed solution of m-phenylenediamine (MPD) and a copolymerized diamine monomer in N,N-dimethylacetamide (DMAC) serving as a solvent using a cosolvent; (2) mixing isophthaloyl chloride (IPC) with the mixed solution of the MPD and the copolymerized diamine monomer in the DMAC, and conducting pre-polycondensation and polycondensation in sequence to obtain a modified PMIA resin solution; and (3) subjecting the modified PMIA resin solution to additive addition, filtration, defoaming, and dry-wet spinning to obtain the modified PMIA fiber. In the device for preparing a modified PMIA fiber by continuous polymerization-dry-wet spinning, a prepolymerization system includes a micro-mixer and a micro-reactor that are connected in sequence, and a micro-channel of the micro-reactor is designed to be heart-shaped; and a polycondensation system is a combination of multi-stage micro-screws. The present disclosure comprehensively solves the problems during preparation of the PMIA fiber. Moreover, an obtained product has a perfect structure, excellent performances, and desirable stability and controllability, and can be prepared through continuous high-efficiency production.

Method, apparatus and system for aftertreatment of exhaust gas comprising inline housing
10486117 · 2019-11-26 · ·

An apparatus for aftertreatment of exhaust gas including a housing having a longitudinal axis that extends between a first end and a second end of the housing; an exhaust inlet being positioned at a portion of the first end of the housing for entering exhaust gas flow into the interior of the housing; a first substrate being positioned within the interior of the housing downstream to the exhaust inlet, wherein the exhaust gas flow being configured to flow through the first substrate in direction of the longitudinal axis; mixer arrangement being positioned within the interior of the housing downstream to the first substrate and including: first flow guide arrangement configured to guide the exhaust gas flow to rotating and advancing gas flow in direction of a crosswise axis perpendicular to the longitudinal axis; a reactant inlet for dispensing reactant to the rotating and advancing gas flow, the reactant configured to mix with the exhaust gas; and second flow guide arrangement configured to guide the rotating and advancing mixed gas flow in direction of the longitudinal axis as a mixed exhaust gas flow; and a second substrate being positioned within the interior of the housing downstream to the mixer arrangement, wherein the mixed exhaust gas flow being configured to flow through the second substrate in direction of the longitudinal axis.

Flow distributor

A flow distribution system for a multi-phase fluid stream includes an inlet for receiving a multi-phase fluid stream from an inlet pipe, a plurality of outlets each for delivering a portion of the multi-phase fluid stream to a respective outlet pipe, and a hollow housing forming an inner chamber in fluid communication with the inlet and the plurality of outlets, where the housing has a central longitudinal axis. The inner chamber includes a first chamber portion adjacent to the inlet and a second chamber portion adjacent to the plurality of outlets, and the first chamber portion has a cross-sectional area that is less than the cross-sectional area of the second chamber portion. A non-planar flow diverter is positioned within the chamber.

MICROFLUIDIC CHIP AND COSMETIC MANUFACTURING APPARATUS INCLUDING SAME

A microfluidic chip and a cosmetic manufacturing apparatus including the microfluidic chip are disclosed. The microfluidic chip contains an inlet portion including a first and a second fluid inlets; a dissolution portion including a first and a second micro flow paths in which a first and a second modular raw materials dissolved by the first and the second fluids are pre-loaded, respectively; a confluence including a third micro flow path in which the first and the second fluids and the first and the second modular raw materials converge; a stir portion including a fourth micro flow path which forms a mixed fluid by mixing the first and the second fluids and the first and the second modular raw materials; and a vortexing portion configured to form a cosmetic composition.