A method of synthesising an organic high explosive includes the steps of i) providing a first solution A, ii) providing a second solution B, wherein the admixture of solution A and solution B are selected such that they are capable upon formation of the admixture of reacting together to provide an organic high explosive, and iii) causing the solution A and B to be mixed and passed through a flow reactor to create an admixture, wherein the flow reactor includes a pipe, wherein the internal diameter of the pipe is selected such that it is less than the critical diameter of the organic high explosive, thereby preventing detonation of the formed organic high explosive in said flow reactor.

Fluidic systems, modules, and associated methods are generally described. In some embodiments, a fluidic system comprises a module which is configured such that fluid may flow therethrough with a relatively uniform time-averaged linear flow rate (i.e., the time-averaged flow rate that is perpendicular to the transverse cross-sectional area) and/or time-averaged flux across the transverse cross-sectional area of the module. Advantageously, such modules may behave in a way such that the time-averaged linear flow rate and/or time-averaged flux exhibits minimal or no dependence on the transverse cross-sectional area thereof. This may allow for modules to be scaled-up in a relatively facile manner by merely increasing the transverse cross-sectional area, which may eliminate or substantially reduce the need for other components of the module to be redesigned upon scale-up. In some embodiments, modules may be scaled-up in a manner that requires no or minimal chemical process adjustments.

A continuous-flow preparation method for an amino alcohol compound using a micro-reaction system. The micro-reaction system includes a feed pump, a micromixer, a microchannel reactor, and a back pressure valve. An aldehyde compound and an amine compound are simultaneously fed to the micro-mixer for mixing to obtain a mixed solution. The mixed solution is directly fed to the micro-channel reactor and undergoes an addition reaction. The reaction mixture is collected, and subjected to concentration, separation and purification to obtain the desired amino alcohol compound.

A smart catalyst support with real-time temperature field monitoring and dynamic regulation in the reaction zone is provided. Specifically for a variety of different properties of the material composition of the three-dimensional porous structure; three-dimensional porous structure using multi-material 3D printing technology and selective carbonization process manufacturing and forming; the three-dimensional porous structure consists of three parts: thermoelectric phase, conductor phase and structural phase, responsible for temperature field perception, temperature field regulation and electrical isolation, respectively; temperature field sensing is realized by the combination of thermoelectric phase and conductor to form a thermocouple using the Seebeck effect; temperature field regulation is realized by generating joule heat to the input current of the conductor phase; the temperature field sensing and temperature field regulation process are interconnected from electrical isolation by structural phase, using the insulation properties of the structural phase to achieve.

Proposed are an automated microreactor for effective optimization of a high-speed chemical reaction, and a method of optimizing a high-speed chemical reaction using the same. The automated microreactor includes a raw material supply unit including a plurality of flow rate controllers that supply a plurality of raw materials and control flow rates of the plurality of raw materials, an intermediate reaction unit including a plurality of micromixers for intermediate that generate a first mixture and a plurality of tubular reactors for intermediate that generate an intermediate product, an intermediate reaction control unit including a valve member, and a product reaction unit including a product micromixer that produces a second mixture and producing a product, through which optimal synthesis conditions (optimal temperature, flow rate, reaction volume and organolithium reagent type) can be achieved to obtain the highest yield in a short time.

The present invention relates to a continuous flow process for synthesis of acephate and its intermediates. The present invention more particularly relates to synthesis of acephate and its intermediates in a microreactor system.