Container, including a body delimiting a cavity to contain fluid substance. A mobile bottom, inside the cavity, sealedly movable along the body internal wall. The body sealedly coupled to a collar having a surface resting on the body and a tubular member extending from the bottom thereof. The tubular member defining a first passage through which the fluid substance flows in use. An insert housed within the collar and formed of first and second parts, connected by a first breakable portion. A shutter housed, in a sealed manner, inside the insert and formed of first and second sections mutually connected by a second breakable portion. The second section including a surface to cooperate, in a sealed manner, with the tubular member when the second section is fitted thereon and a breakable wall which, when broken, permits access to the cavity.

A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.