Described herein are methods and systems useful for interrogating protein-protein interactions. These systems utilize non-functional fragments of polypeptides that can complement each other to form a fully functional fragment in vivo. The fully functional polypeptide releases a transcription regulating polypeptide that can bind and activate or repress a reporter element.

A system includes sensor-actuator units fixed onto a plate to be actuated according to at least one predetermined vibratory mode, each sensor-actuator unit having an electromechanical actuator and a deformation or vibratory speed sensor, wherein the electromechanical actuator and the sensor are colocated on the surface, that is to say that the measurement by the sensor is performed in immediate proximity to the electromechanical actuator, this proximity being such that the actuator and the sensor can respectively actuate and measure the same predetermined vibratory mode.

A system and method for driving a medical probe. The system including a processor configured to apply respective harmonic electrical signals to two or more piezoelectric crystals coupled with a tip of the medical probe so as to cause the tip to vibrate; and a balancer, which is configured to iteratively adjust the signals to equalize a selected parameter of the signals, so as to cause the tip to vibrate at a predefined trajectory. The method including applying respective harmonic electrical signals to two or more piezoelectric crystals coupled with a tip of the medical probe so as to cause the tip to vibrate. The signals are iteratively adjusted to equalize a selected parameter of the signals, so as to cause the tip to vibrate at a predefined trajectory.

A vibration device is provided that includes a vibration element with a piezoelectric vibrator and a driving device that causes the vibration element to vibrate. The vibration element includes a translucent body and the piezoelectric vibrator is electrically coupled to the driving device. The driving device includes a first circuit that applies an electric signal to the piezoelectric vibrator to render the vibration element in a resonant state, a second circuit that applies an electric signal to the piezoelectric vibrator according to a feedback signal output from the piezoelectric vibrator, and a switch that switches coupling between the first circuit and the piezoelectric vibrator and coupling between the second circuit and the piezoelectric vibrator at a certain timing.

Micromachined ultrasonic transducer (MUT) arrays capable of multiple resonant modes and techniques for operating them are described, for example to achieve both high frequency and low frequency operation in a same device. In embodiments, various sizes of piezoelectric membranes are fabricated for tuning resonance frequency across the membranes. The variously sized piezoelectric membranes are gradually transitioned across a length of the substrate to mitigate destructive interference between membranes oscillating in different modes and frequencies.

Control console for a powered surgical tool that includes a transformer with a secondary winding across which the tool drive signal is present. Also internal to the transformer is a matched current source that consists of a leakage control winding and a capacitor. The current sourced by the matched current at least partially cancels out leakage current that may be present.

A multi-frequency ultrasound therapy apparatus is configured to operate at its center frequency and at the higher harmonic of its center frequency. The center frequency can be for the entire apparatus or for each ultrasound source element. At least one source element can generate ultrasound energy at its center frequency while, simultaneously, at least another source element can generate ultrasound energy at the higher harmonic of its center frequency. In addition, the same source element can generate ultrasound energy at its center frequency and the higher harmonic of its center frequency, respectively, but at different times. A data storage unit that stores encrypted and encoded data is disposed on the apparatus. The encoded data includes a unique identification code of the apparatus, the condition of use of the apparatus, the center frequency of each source element, the ultrasound efficiency of each source element, and/or other parameters relating to the apparatus.

The present invention includes: an ultrasonic horn (14) to which two ultrasonic vibrations can be input to excite a capillary (15) mounted to a front end with different frequencies in a Y-direction and an X-direction; and a control unit (50) which adjusts the respective magnitude of the two ultrasonic vibrations. The Y-direction is a direction in which the ultrasonic horn (14) extends. The control unit (50) adjusts the respective magnitude of the two ultrasonic vibrations to adjust a ratio (ΔY/ΔX) of amplitude of the capillary (15) in the Y-direction and the X-direction. Thus, degradation in the quality of the joining between wires and leads is suppressed.

A mini subwoofer double drive low-frequency vibrator includes a base, an upper cover, a side cover, a flexible printed circuit, a coil, a magnetic body, a counterweight, a spring piece, an internal welding piece, an external welding piece, an insulating tape, and a buffer. The magnetic body and the coil includes a symmetrical double-driving structure at both upper and lower part to mutually offset components in a non-vibration direction of an electromagnetic force and cancel vibration noises. The spring piece adopts a V-shape structure to increase an effective length of a deformation zone and to make a response frequency even lower. Two V-shape springs are distributed symmetrically in a center, making an operation more stable. The buffer is adopted to enhance service life, for fear of a spring damage caused by high circuit voltage.

Aspects of the technology described herein relate to sensing a fingerprint of a subject via an ultrasound fingerprint sensor. Certain aspects relate to transmitting and receiving ultrasound data at multiple different frequencies to provide sensing data from different depths within the skin of the subject. Since different ultrasound frequencies are expected to penetrate a subject's skin to different degrees, sensing a finger at multiple ultrasound frequencies may provide information on different physical aspects of the finger. For instance, sound ultrasound frequencies may sense a surface of the skin, whereas other ultrasound frequencies may penetrate through one or more of the epidermal, dermal or subcutaneous layers. The ultrasound fingerprint apparatus may have utility in various applications, including but not limited to mobile electronic devices, such as mobile phones or tablet computers, a laptop computer or biometric access equipment.