A therapy apparatus for treating tissue by the emission of focused ultrasound waves, including:

a creation surface of a pressure field of focused ultrasound waves divided into at least N sectors having segments of asymmetrical concave curve (S1, S2, . . . ) with centres of curvature;

centres of curvature (c.sub.1, c.sub.2, . . . ) asymmetrical to the extent where the centres of curvature are situated at different distances from the plane of symmetry (A1) or from the axis of symmetry (S) and/or at different depths taken according to the axis of symmetry;

the individual axes (a.sub.1, a.sub.2, . . . ) intersecting between the focal zones (Zc.sub.1, Zc.sub.2, . . . ) and the creation surface (8) or beyond the focal zones such that the beams originating from the sectors intersect to create a focal coverage zone (Zr) which is off-axis relative to the plane of symmetry (A1) or to the axis of symmetry (S);

the sectors of this creation surface (8) creating energy deposit zones with profiles corresponding to the focal coverage zones (Zr).

An intraluminal imaging device includes a flexible elongate member sized and shaped for insertion into a vessel of a patient, the flexible elongate member including a proximal portion and a distal portion; an imaging assembly positioned at the distal portion of the flexible elongate member; and a bridge member at electrical ground and in contact with at least a portion of the imaging assembly to maintain the at least portion of the imaging assembly at electrical ground, wherein the bridge member is disposed in cylindrical configuration. Associated devices, systems, and methods are also provided.

A method for generating a mechanical wave, including generating a high amplitude mechanical pulse; coupling the mechanical pulse in a proximal end of a transmission member; propagating the mechanical pulse into the transmission member from the proximal end and a distal end thereof; and transmitting the mechanical pulse at the distal end.

Devices, systems, and methods relating to intraluminal imaging are disclosed. In an embodiment, an intraluminal imaging device is disclosed. One embodiment of the intraluminal imaging device comprises a flexible elongate member configured to be inserted into a body lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion. The intraluminal imaging device further comprises an ultrasound imaging assembly disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly comprises a support member, a flexible substrate positioned around the support member and including a proximal region and a distal region, the proximal region comprising a plurality of cutouts defining a plurality of substrate ribbons, a plurality of transducer elements integrated in the distal region of the flexible substrate, and a plurality of control circuits disposed on the proximal region of the flexible substrate.

An ultrasound probe includes: an ultrasound transducer including plural piezoelectric elements; an acoustic lens layer configured to radiate the ultrasound emitted from the plural piezoelectric elements to outside; a back layer that faces the acoustic lens layer with the ultrasound transducer interposed between the back layer and the acoustic lens layer; and a wiring member having at least a part that is arranged at a first position between the acoustic lens layer and the ultrasound transducer or at a second position that faces the ultrasound transducer with the back layer interposed between the second position and the ultrasound transducer. The wiring member includes: a resin layer having electrically insulating; and an electrically conducting layer that is provided on the resin layer and includes plural signal wirings.

An intraluminal ultrasound imaging device includes a flexible elongate member configured to be inserted into a body lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion. The device includes an ultrasound scanner assembly disposed at the distal portion of the flexible elongate member. The ultrasound scanner assembly includes a flexible substrate comprising a longitudinal width extending from an inner edge to an outer edge; a control region embedded in the flexible substrate; a transducer region embedded in the flexible substrate; and a window region disposed between the outer edge of the flexible substrate and the transducer region, and wherein the window region, the transducer region, and the control region are radially arranged relative to one another. Associated devices, systems, and methods are also described.

Intraluminal ultrasound imaging device, systems and methods are provided. In some embodiments, the intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient, and an ultrasound scanner assembly disposed at a distal portion of the flexible elongate member and configured to obtain imaging data of the body lumen. The ultrasound scanner assembly includes a flexible substrate, a first under-bump metallization (UBM) layer over the flexible substrate, a first solder feature over the first UBM layer, and a first electronic component electrically connected to the first solder feature.

An intraluminal ultrasound imaging device includes a flexible elongate member configured to be inserted into a body lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion. The device also includes an ultrasound scanner assembly disposed at the distal portion of the flexible elongate member. The ultrasound scanner assembly includes a flexible substrate; a transducer region positioned on the flexible substrate; and a control region positioned on the flexible substrate, wherein the transducer region and the control region are radially arranged relative to one another. Associated devices, systems, and methods are also described.

A method for disrupting solid materials suspended in a fluid medium includes introducing a fluid comprising solid materials dispersed in a fluid medium into a fluid duct, flowing the fluid through an annular space between a cylindrical wall of the fluid duct and an outer surface of a cylindrical acoustic projector that is concentric with the cylindrical wall, the acoustic projector comprising a plurality of hammer elements spaced apart from one another by a first plurality of slots in the acoustic projector, supplying electrical energy to a transducer coupled to the acoustic projector to cause the acoustic projector to vibrate, thereby causing cavitations in the fluid, and flowing the fluid through an outlet of the disruptor after the fluid has been exposed to the cavitations. The cavitations can disrupt solid materials such as pulp, flowers, stems and seeds to release juice or oils from the materials.

An apparatus for disrupting solid materials suspended in a fluid medium includes a plurality of hammer elements that transfer acoustic energy from an acoustic transducer into a concentration zone between heads of the hammer elements and inner walls of a fluid duct which act as an anvil, thereby causing cavitations to form within the concentration zone. The transducer may be a cylindrical transducer compression fit into an acoustic projector from which the hammer elements extend towards a distal end, and mass balance elements extend towards a proximal end. The apparatus can be used to efficiently extract juice from fruit pulp, separate oils from plant matter, and process various organic and inorganic materials.