An operational unit for locating and neutralizing pathogen cells in blood includes a cassette which has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates the holding chambers and passes light to an underlying sensor array such that the cells in the blood selectively block the light to produce shadow images of the cells. A processor performs pattern recognition to locate the pathogen cells by use of an image library. After the pathogen cells are located, a source of ultraviolet light is activated and UV light is passed through selectively controlled shutters to illuminate only the limited areas that have the identified pathogen cells. Sufficient ultraviolet light energy is applied to destroy the identified cells. A pump refills the cassette holding chambers, returns the neutralized-pathogen blood to the patient, and the process is repeated.

Provided herein are compositions and kits including a pathogen-inactivated cryoprecipitate suitable for infusion into a subject at least 1 day after thawing. The methods are useful in the efficient preparation of cryoprecipitates with desirable characteristics, including pathogen-inactivated cryoprecipitates that are suitable for infusion into a subject at least 1 day after thawing.

A peritoneal dialysis (PD) disinfection device includes a top made of a material configured to let light pass through the material, a bottom, a printed circuit board (PCB) secured between the top and the bottom, a plurality of ultraviolet light emitting diodes (UV-LEDs) secured to the PCB, and a power source operable to supply power to the plurality of UV-LEDs. At least one of the top, the bottom, and the PCB includes a feature that enables a patient to locate and orient the PD disinfection device so that UV light from the plurality of UV-LEDs is directed towards a connection end of the patient's catheter or a catheter/patient exit site.

Provided are a moist-heat sterilized nimodipine composition free of ethanol and phospholipid and a method for preparing the same. The composition comprises (1) nimodipine; (2) a non-phospholipid surfactant selected from polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil, polyoxyl 15 hydroxystearate, D-alpha-tocopherol polyethylene glycol 1000 succinate (TPGS), polysorbates, glyceryl monocaprylocaprate, or any mixture of two or more thereof; and (3) a co-solvent, which is propylene glycol.

A method and products are provided for in situ generation of a disinfectant composition for the treatment of organic matter. The method comprises bringing together a first reagent (12) and a second reagent (14) via a membrane (15) to generate the disinfectant composition. A pouch (10) for use in the method comprises a first section (11) for housing the first reagent (12) and a second section (13) for housing the second reagent (14). The pouch (10) further comprises a membrane (15) adapted in use to permit the first reagent (12) and the second reagent (14) to be brought together, thereby to generate the disinfectant composition. The pouch (10) can be incorporated into the structure of a bag (17) or packaging having a chamber for the organic matter, the pouch (10) being arranged such that the generated disinfectant composition is dispensed into the chamber.

A method for removing organic pollutants from water bodies by activating persulfate with nutrient-enhanced soybean sprout-based biochar involves a method for removing organic pollutants from water bodies by activating persulfate with biochar. The invention is intended to solve the technical problems that existing biochar materials show poor catalytic activity when used for activating persulfate and requires the addition of a large amount of modifiers, which easily leads to secondary pollution to the environment, and the existing biochar materials are susceptible to interference from halogen ions, oxoanions, and natural organic matters in a persulfate system. The raw material of a catalyst used in the invention is soybean, and has an activation process mainly based on non-radical activation, exhibiting high reaction rate and saving persulfate. With the addition of 0.2 g/L catalyst and 0.5 mM potassium persulfate, the degradation efficiency against 10 mg/L phenol can reach 100% within 10 min.

An improved mobile apparatus for sterilizing surgical trays serves as a self-contained autoclave, allowing sterilization of the interior of the apparatus and its contents. A method of sterilization using the apparatus is presented as well. By means of a dedicated transfer and storage system, the apparatus, integrable with respect to a transfer cart and a lift device, may be moved easily between a location of sterilization, a storage area, and an operating room, and more than one such apparatus may be stacked vertically for storage to enhance storage efficiency.

Provided herein are embodiments for a wearable or portable dialysis system. The wearable or portable dialysis system includes a dialysis machine including a pump to move dialysate through a filtering component thereof. The wearable or portable dialysis system further includes an electric circuit in communication with the dialysis machine for controlling electronic components of the dialysis machine. The filtering component includes an electricity generation and purification membrane (EPM) in a filtering path of the filtering component, and the EPM is coupled to the electric circuit. In response to dialysate moving through the filtering path of the filtering component, electricity is generated by the EPM and provided to the electric circuit to power the electronic components of the dialysis machine.

Collagen-based tissue matrices are treated in a reactor by a flow of supercritical carbon dioxide, including at least one chemical additive inserted via an insertion device that is in communication with a loop. The additive is injected into the liquid or supercritical carbon dioxide when the reactor is already pressurized. The method combines supercritical CO.sub.2 as a solvent and a chemical additive as a co-solvent, in a dynamic treatment flow which circulates in the loop associated with the reactor, in order to increase their action on the treated tissue. The circulation of an additive, which is progressively injected and then recirculated with the CO.sub.2, forms part of a first treatment cycle. Several cycles, each with an additive, may follow one after the other, separated by a step of separating out the additive and the CO.sub.2, which is carried out with or without maintaining the pressurization and the circulation of CO.sub.2.

Mounting hardware for a faucet including one or more light sources for illumination. The light source(s) can be configured to emit light from one or more vertically oriented surfaces of the mounting hardware. One or more sensors can acquire sensor data that can be used to control operation of the light source(s). The light sources can include visible and/or ultraviolet light sources. When included, the ultraviolet light can be directed onto one or more areas of one or more horizontally oriented surfaces located adjacent to the vertically oriented surface(s). The light sources can be located in an escutcheon of the mounting hardware.