A method for preparing a filtered beverage includes filtering a raw beverage using a cross-flow ultrafiltration device to produce a solids fraction and a liquid fraction; heating the solids fraction to a temperature of 60 C. or greater to produce a pasteurized solids fraction; microfiltering the liquid fraction through a microfilter having a size cut-off of 1 m or smaller to produce a microfiltered liquid fraction; and combining the pasteurized solids fraction and the microfiltered liquid fraction to result in the filtered beverage.

A method for preparing a filtered beverage includes filtering a raw beverage using a cross-flow ultrafiltration device to produce a solids fraction and a liquid fraction; heating the solids fraction to a temperature of 60 C. or greater to produce a pasteurized solids fraction; microfiltering the liquid fraction through a microfilter having a size cut-off of 1 m or smaller to produce a microfiltered liquid fraction; and combining the pasteurized solids fraction and the microfiltered liquid fraction to result in the filtered beverage.

Systems, devices and methods for controlled intramedullary delivery of light (frequencies from about 380 nm to about 500 nm) to treat tissue or bones disorders, including osteomyelitis, by a flexible fiber are provided, where the light is delivered in a circumferential fashion around the fiber, and where the energy delivered from the fiber is of a similar average intensity at the front end and back end of the fiber, and in between. The methods and systems deliver intramedullary light to the canal over long lengths via a minimally invasive pathway to a bone. The methods and systems deliver and maintain a light delivery system within the canal of the bone to provide single or multiple doses of light to kill, eliminate, remove or reduce bacteria, viruses, fungus and pathogens, without removal of the light fiber system, thereby providing single or multiple treatments.

A food preservative having antimicrobial and antioxidant activity and a method of fabrication. The food preservative includes an inner core including an extract of pomegranate peels and onion peels, and an outer coating of chia nano particles. The outer coating encapsulates the inner core.

A face is maintained for transplant by circulating perfusate in through vascular vessels of a face after removal from a donor until transplant. The method includes placing a transplantable face on a support that maintains its preexisting structural shape within a chamber. Circulation is maintained by pumping a perfusate from a reservoir through vascular vessels, collecting perfusate from the chamber and returning it to the reservoir for recirculation. Prior to recirculating the collected perfusate it is filtered and irradiated with radiant energy thereby inactivating pathogens. Prior to return the collected perfusate is oxygenated and purified by dialysis with the dialysate being recharged by being passed through an ion exchange medium.

Provided are methods and systems for the pathogen inactivation of blood products and compositions, including methods of using devices (e.g., comprising component(s) configured to control flow of fluid(s)) to determine the amount of pathogen inactivation compound (PIC) necessary for pathogen inactivation of a blood composition (e.g., based at least in part on one or more input parameters) and allow transfer of the blood composition and the PIC into a container, e.g., of a processing set.

A transfer device for enabling an aseptic transition between a first object, in particular a first process unit, and a second object, in particular a second process unit. Furthermore, a system consisting of at least two objects, in particular process units, and to a system consisting of three or four or more objects and/or process units.

Methoxy polyethylene glycol for use as a medicament, in particular in skin healing, wound healing and treatment of a microbial infection. A method for treating a medical device and/or implant to reduce or eliminate microbial contamination comprises applying a liquid formulation comprising methoxy polyethylene glycol. This invention relates to the novel discovery that methoxy polyethylene glycol, an inactive polymer with no known pharmacological effect, was able to come between microbes and a surface, removing the microbes or releasing the attachment or adherence of the microbes to the surface and thereby improving wound healing significantly, eliminating infections and colonies of microbes.

Packaging for prosthetic heart valves including an assembly for stabilizing dry prosthetic tissue implants such as heart valves during storage. The packaging assembly includes a primary sterile barrier that permits gas sterilization of the tissue implant, and a secondary sterile barrier that also prevents oxidation of the implant during long-term storage. Tissue heart valves may be placed or suspended within a cavity of an inner rigid tray with a gas-permeable lid sealed thereon, and a cap placed over the cavity to limit movement of the valve therein. The inner tray is placed within an outer sterile barrier, such as another rigid tray or a flexible pouch, and the assembly is then sterilized. The outer sterile barrier may include a double seal so that a first gas-permeable seal can be closed for sterilization, after which a second gas-impermeable seal can be closed to seal out any further oxygen contact with the tissue implant. Alternatively, the inner tray may be placed within a sterile pouch and the assembly gas-sterilized, and then the entire assembly is placed within another pouch that provides an impermeable barrier to the surrounding atmosphere to prevent oxidation of the tissue implant.

The invention concerns a method for the manipulation of sterilized objects (22, 23, 24) in a controlled atmosphere chamber (12), comprising a step of gripping at least one of the sterilized objects (22, 23, 24) from the outside of the chamber (12), and a step of inserting the latter inside the chamber (12) through an access aperture defined in correspondence with at least one wall (15, 16) thereof, subsequently a step of closing the access aperture and a step of decontaminating the interior of the chamber (12) by delivering a decontaminating agent.