The present invention relates to a compound of dihydrophaseic acid 3′-O-beta-D-glucopyranoside for the prevention and treatment of osteoporosis. It was found that the D3G isolated from the Lycium root bark extract induces the activity of osteoblast differentiation while promoting the proliferation of pre-osteoblast, and promotes the bone remodeling by promoting the differentiation of both osteoblast and osteoclast when mixing and culturing pre-osteoblast which is the precursor of osteoblast, and monocyte which is the precursor of osteoclast. Therefore, the D3G of the present invention is expected to be useful as a pharmacological agent or functional food effective for the prevention and treatment of osteoporosis which is a disease caused by the abnormal balance of bone remodeling.

The present invention relates to a compound of dihydrophaseic acid 3′-O-beta-D-glucopyranoside for the prevention and treatment of osteoporosis. It was found that the D3G isolated from the Lycium root bark extract induces the activity of osteoblast differentiation while promoting the proliferation of pre-osteoblast, and promotes the bone remodeling by promoting the differentiation of both osteoblast and osteoclast when mixing and culturing pre-osteoblast which is the precursor of osteoblast, and monocyte which is the precursor of osteoclast. Therefore, the D3G of the present invention is expected to be useful as a pharmacological agent or functional food effective for the prevention and treatment of osteoporosis which is a disease caused by the abnormal balance of bone remodeling.

The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and cystatin and/or cystatin hydrolysate in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.003 to 0.6.

The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and cystatin and/or cystatin hydrolysate in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.003 to 0.6.

Dietary supplements and formulations for a subject, including veterinary animals and humans, in an oral preparation and/or parenteral preparation, are provided. The formulations comprise elevated amounts of hydrolyzed collagen, a glucosamine salt, a glycosaminoglycan, a sulfone, a polysaccharide acid, an ascorbate salt, a transition metal, and a polyunsaturated fatty acid. A method for enhancing joint health and/or joint repair in a subject, including veterinary animals and humans, having a joint disorder or a disease associated therewith, is also provided, comprising administering the preparation comprising high amounts of hydrolyzed collagen.

A type I collagen or elastin production promoter containing a mycosporine-like amino acid or a salt thereof as an active ingredient; and a method for promoting type I collagen or elastin production, the method including administering an effective amount of a mycosporine-like amino acid or a salt thereof.

A type I collagen or elastin production promoter containing a mycosporine-like amino acid or a salt thereof as an active ingredient; and a method for promoting type I collagen or elastin production, the method including administering an effective amount of a mycosporine-like amino acid or a salt thereof.

The present invention provides a poultry feed or drinking water composition comprising a stable, bioavailable silicon complex formed between silicic acid having free hydroxyl groups and at least one stabilizing agent based on phenol or polyphenol; said poultry feed or drinking water composition for improving bone strength and a method of breeding poultry by feeding to said poultry a feed or drinking water composition comprising a stable, bioavailabie silicon complex formed between silicic add having free hydroxyl groups and at least one stabilizing agent based on phenol or polyphenol.

The present invention provides a poultry feed or drinking water composition comprising a stable, bioavailable silicon complex formed between silicic acid having free hydroxyl groups and at least one stabilizing agent based on phenol or polyphenol; said poultry feed or drinking water composition for improving bone strength and a method of breeding poultry by feeding to said poultry a feed or drinking water composition comprising a stable, bioavailabie silicon complex formed between silicic add having free hydroxyl groups and at least one stabilizing agent based on phenol or polyphenol.

A compound composition for improving bone health and preparation and application thereof are provided. The compound composition is prepared by combining a traditional Chinese medicine extract with chicken cartilage collagen, magnesium, vitamin K2 and vitamin D3. The compound composition overcomes the food safety risk of the existing osteoporosis preventive drugs by adding the traditional Chinese medicine extract for improving osteoporosis and promoting bone health. And the compound composition disclosed can be used as a dietary supplement or health food raw material for preventing or treating osteoporosis. Therefore, the compound composition disclosed is suitable for promotion and application.