A prophylactic agent for spontaneous cancer may contain a plant fermentation product as a mixture of (a) to (g), fermentation products of: (a) barley, black soybean, red rice, black rice, adzuki bean, adlay, Japanese barnyard millet, foxtail millet, and/or proso millet; (b) mandarin orange, grape, apple, Vitis coignetiae berry, peach, persimmon, papaya, Japanese pear, watermelon, Japanese apricot, fig, Chinese quince fruit, kabocha squash, kumquat, Yuzu, loquat fruit, apricot, jujube, chestnut, matatabi fruit, and/or Japanese plum; (c) purple sweet potato, Jerusalem artichoke, carrot, onion, sweet potato, taro, Japanese wild yarn, daikon, red turnip, great burdock, lotus root, yacon, lily bulb, arrowhead, ginger, garlic, and/or turmeric; (d) cabbage, perilla, Moms leaf, fish mint, Japanese mugwort, Sasa veitchii, and/or dandelion; (e) kelp, wakame, and/or mozuku; (f) black sesame, walnut, and/or ginkgo nut; and (g) maitake and/or shiitake. A SAM evaluation system and/or SAMP mouse may evaluate such cancers and/or substances thereon.

The invention relates to preparation comprising at least one probiotic strain belonging to the genus Bacillus megaterium, and a polyunsaturated fatty acid component comprising at least one omega-3 or omega-6 fatty acid selected from eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), arachidonic acid (ARA), alpha linolenic acid, stearidonic acid, eicosatetraenoic acid, docosapentaenoic acid, linoleic acid, γ-linolenic acid, wherein the polyunsaturated fatty acid component comprises an omega-3 or omega-6 fatty acid salt. The invention further relates to use of the inventive preparation as a feed or food supplement, pharmaceutical product, feed-or foodstuff compositions and for topical applications.

The invention relates to preparation comprising at least one probiotic strain belonging to the genus Bacillus megaterium, and a polyunsaturated fatty acid component comprising at least one omega-3 or omega-6 fatty acid selected from eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), arachidonic acid (ARA), alpha linolenic acid, stearidonic acid, eicosatetraenoic acid, docosapentaenoic acid, linoleic acid, γ-linolenic acid, wherein the polyunsaturated fatty acid component comprises an omega-3 or omega-6 fatty acid salt. The invention further relates to use of the inventive preparation as a feed or food supplement, pharmaceutical product, feed-or foodstuff compositions and for topical applications.

The present invention pertains to an anticancer composition containing IF1 (ATPase inhibitory factor 1). The IF1 (ATPase inhibitory factor 1) according to the present invention has the effect of releasing extracellular ATP, induces cytotoxicity in various cancer cells and exhibits anticancer efficacy, and is thus very useful as an active ingredient of a powerful anticancer agent.

The present invention pertains to an anticancer composition containing IF1 (ATPase inhibitory factor 1). The IF1 (ATPase inhibitory factor 1) according to the present invention has the effect of releasing extracellular ATP, induces cytotoxicity in various cancer cells and exhibits anticancer efficacy, and is thus very useful as an active ingredient of a powerful anticancer agent.

The present invention relates to a composition for preventing, treating or improving a prostate disease containing Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora extracts as an active ingredient. According to the present invention, the complex extract of Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora has an effect of inhibiting the activity of 5α-reductase associated with benign prostatic hyperplasia and has an advantage of having a few or no side effects of reducing a male sexual function by using a synthetic compound in the related art using ingredients derived from natural plants. Further, it is confirmed that in a complex extract obtained by mixing Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora extracts at a more proper ratio, the 5α-reductase inhibitory activity is significantly excellent.

The present invention relates to a composition for preventing, treating or improving a prostate disease containing Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora extracts as an active ingredient. According to the present invention, the complex extract of Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora has an effect of inhibiting the activity of 5α-reductase associated with benign prostatic hyperplasia and has an advantage of having a few or no side effects of reducing a male sexual function by using a synthetic compound in the related art using ingredients derived from natural plants. Further, it is confirmed that in a complex extract obtained by mixing Acanthopanax sessiliflorus, Phragmites rhizome, and Pinus densiflora extracts at a more proper ratio, the 5α-reductase inhibitory activity is significantly excellent.

Healthful supplements are described herein. For example, the supplements can include at least four of the following types of nutrients: an amino acid blend, a coconut extract, a vegetable glycerin extract, an alcohol blend, a cannabinoid blend, a hemp plant extract, a Boswellia serrata extract, a curcuma/turmeric blend, black cumin seed, an Artemisia ludoviciana extract, an Astragalus extract, a fenugreek extract, a mushroom extract blend, or any combination thereof.

Healthful supplements are described herein. For example, the supplements can include at least four of the following types of nutrients: an amino acid blend, a coconut extract, a vegetable glycerin extract, an alcohol blend, a cannabinoid blend, a hemp plant extract, a Boswellia serrata extract, a curcuma/turmeric blend, black cumin seed, an Artemisia ludoviciana extract, an Astragalus extract, a fenugreek extract, a mushroom extract blend, or any combination thereof.

The invention relates to pharmaceutical compositions comprising calcium lactate as an active agent and a polysaccharide, polymer, lipid, or a combination thereof. The pharmaceutical compositions are useful treating cancer. The invention also relates to foods and nutrient compositions comprising calcium lactate.