The invention relates to a human milk oligosaccharide (HMO) for use in reducing or preventing fatigue and/or improving focus or concentration on a mental or physical activity in a human. The invention also relates to a synthetic composition for use, comprising one or more of said HMOs. The invention further relates to a method for reducing or preventing fatigue and/or improving focus or concentration on a mental or physical activity by administering at least one HMO and the use of said one or more HMOs in a dietary management of a human.

The invention relates to a human milk oligosaccharide (HMO) for use in reducing or preventing fatigue and/or improving focus or concentration on a mental or physical activity in a human. The invention also relates to a synthetic composition for use, comprising one or more of said HMOs. The invention further relates to a method for reducing or preventing fatigue and/or improving focus or concentration on a mental or physical activity by administering at least one HMO and the use of said one or more HMOs in a dietary management of a human.

A method for treating a sleep disorder according to an embodiment of the present disclosure includes administering a composition comprising an extract of Hibiscus syriacus as an effective ingredient to a subject in need thereof. Because the Hibiscus syriacus extract of the present invention has an effect of improving sleep time deteriorated by stress, and an effect of reducing the content of corticosterone, which increases due to stress, and increasing the content of serotonin in blood. In addition, the composition has an effect of enhancing in a significant sense the expression of GABAR A α1 in cerebral cortex, which decreases due to stress, in a group administered with Hibiscus syriacus extract. As such, the composition comprising Hibiscus syriacus extract as an effective ingredient as an effective ingredient can be advantageously used as a functional health food composition or a pharmaceutical composition for preventing, ameliorating or treating sleeping disorders.

A method for treating a sleep disorder according to an embodiment of the present disclosure includes administering a composition comprising an extract of Hibiscus syriacus as an effective ingredient to a subject in need thereof. Because the Hibiscus syriacus extract of the present invention has an effect of improving sleep time deteriorated by stress, and an effect of reducing the content of corticosterone, which increases due to stress, and increasing the content of serotonin in blood. In addition, the composition has an effect of enhancing in a significant sense the expression of GABAR A α1 in cerebral cortex, which decreases due to stress, in a group administered with Hibiscus syriacus extract. As such, the composition comprising Hibiscus syriacus extract as an effective ingredient as an effective ingredient can be advantageously used as a functional health food composition or a pharmaceutical composition for preventing, ameliorating or treating sleeping disorders.

This invention relates to the use of a nutritional composition comprising sialylated oligosaccharides for enhancing cognitive development and learning skills in mammals. The nutritional composition comprises 3′-Siallylactose (3′-SL) and 6′-Siallylactose (6′-SL) in a weight ratio between 10:1 and 1:10 and is specifically for use in enhancing learning skills and/or enhancing memory function in an individual by increasing the sialic acid (Neu5Ac) concentration in the brain of said individual.

This invention relates to the use of a nutritional composition comprising sialylated oligosaccharides for enhancing cognitive development and learning skills in mammals. The nutritional composition comprises 3′-Siallylactose (3′-SL) and 6′-Siallylactose (6′-SL) in a weight ratio between 10:1 and 1:10 and is specifically for use in enhancing learning skills and/or enhancing memory function in an individual by increasing the sialic acid (Neu5Ac) concentration in the brain of said individual.

Described herein are pet food compositions comprising—in relevant part—neutral detergent fiber and crude fiber in amounts, which are effective in inducing satiety and supporting healthy weight management. Methods of making and using these pet food compositions are also described.

Described herein are pet food compositions comprising—in relevant part—neutral detergent fiber and crude fiber in amounts, which are effective in inducing satiety and supporting healthy weight management. Methods of making and using these pet food compositions are also described.

The disclosure provides a method of improving the cognitive function of an animal by providing a composition containing beta-casein, wherein at least 75% by weight of the beta-casein is a beta-casein variant that does not produce BCM-7 on digestion in the gut of the animal.

The disclosure provides a method of improving the cognitive function of an animal by providing a composition containing beta-casein, wherein at least 75% by weight of the beta-casein is a beta-casein variant that does not produce BCM-7 on digestion in the gut of the animal.