Inorganic anions nitrate and nitrite influence metabolic rate and glucose homeostasis. Infusion of nitrite iv caused an acute drop in resting energy expenditure (oxygen consumption) and nitrate, when given perorally, caused a reduction in oxygen consumption during exercise and a depression of the increase in blood glucose observed after an oral glucose tolerance test. The doses of nitrate and nitrite did not cause any detectable change in methemoglobin levels of blood. Also, nitrate and nitrite did not alter lactate levels in blood. This discovery provides useful treatments to regulate the energy expenditure and glucose homeostasis of a mammal by administration of inorganic nitrite and/or nitrate.

The present invention relates to microbiota compositions and their preparation methods and uses. Particularly, the present invention provides microbiota compositions collected from a dual-specificity phosphatase 6 (dusp6) deficient mammal, which is effective in altering a relative abundance of gut microbiota and also useful in reducing body weight, fat mass, and/or size of adipocytes and increasing oxygen consumption and/or energy expenditure and thus can be used to treat or prevent obesity or its associated disorders or conditions in a subject in need.

The present invention relates to microbiota compositions and their preparation methods and uses. Particularly, the present invention provides microbiota compositions collected from a dual-specificity phosphatase 6 (dusp6) deficient mammal, which is effective in altering a relative abundance of gut microbiota and also useful in reducing body weight, fat mass, and/or size of adipocytes and increasing oxygen consumption and/or energy expenditure and thus can be used to treat or prevent obesity or its associated disorders or conditions in a subject in need.

Disclosed is a food composition which promotes lymphatic circulation in the body to improve the environment around the cells and to help normal metabolism of the cells. The food composition according to the present invention includes cnidium, maple syrup, dried bigarade orange, bambusae succus, kalopanax and coix in the form of powder, liquid or extract.

Disclosed is a food composition which promotes lymphatic circulation in the body to improve the environment around the cells and to help normal metabolism of the cells. The food composition according to the present invention includes cnidium, maple syrup, dried bigarade orange, bambusae succus, kalopanax and coix in the form of powder, liquid or extract.

Amino acid compositions for promoting vascular endothelial health include arginine, citrulline, and taurine. Compositions may be combined with additional ingredients to form beverages, concentrates, and non-liquid food compositions. Methods of making concentrate compositions, beverage compositions, and non-liquid food compositions are provided. Methods of administering compositions to improve endothelial health, treat endothelial dysfunction, treat sexual dysfunction, treat altitude sickness, treat decompression sickness, treat jet lag, and treat fatigue include administering compositions including arginine, citrulline, and taurine.

Amino acid compositions for promoting vascular endothelial health include arginine, citrulline, and taurine. Compositions may be combined with additional ingredients to form beverages, concentrates, and non-liquid food compositions. Methods of making concentrate compositions, beverage compositions, and non-liquid food compositions are provided. Methods of administering compositions to improve endothelial health, treat endothelial dysfunction, treat sexual dysfunction, treat altitude sickness, treat decompression sickness, treat jet lag, and treat fatigue include administering compositions including arginine, citrulline, and taurine.

The present invention relates to compositions comprising a water soluble tomato extract (WSTE) which may be used in maintaining cardiovascular health, lessening the risk of developing cardiovascular health problems, or reducing the likelihood of worsening an existing cardiovascular health problem in a subject exposed, or is at risk of exposure, to particulate air pollution.

The present invention relates to compositions comprising a water soluble tomato extract (WSTE) which may be used in maintaining cardiovascular health, lessening the risk of developing cardiovascular health problems, or reducing the likelihood of worsening an existing cardiovascular health problem in a subject exposed, or is at risk of exposure, to particulate air pollution.

Amino acid formulations for cardiac vitality. The formulations comprise a mixture of a plurality of amino acids, wherein the mixture comprises at least one amino acid selected from the group consisting of serine, threonine, histidine, and/or proline, and optionally arginine Methods of enhancing smooth muscle cell vitality, stabilizing cardiac health, and decreasing oxidative stress and inflammation are also described.