The present invention relates to fiber compositions comprising fiber derived from onion and soluble fiber. Additionally, the invention relates to food products comprising said fiber compositions. In another aspect, the invention relates to methods for obtaining said fiber compositions as well as to the cosmetic uses and therapeutic uses thereof in the treatment and/or prevention of metabolic diseases, colon cancer and bowel inflammation.

The present invention relates to fiber compositions comprising fiber derived from onion and soluble fiber. Additionally, the invention relates to food products comprising said fiber compositions. In another aspect, the invention relates to methods for obtaining said fiber compositions as well as to the cosmetic uses and therapeutic uses thereof in the treatment and/or prevention of metabolic diseases, colon cancer and bowel inflammation.

The present invention relates to cultivation of a selenium-rich Cyclocarya paliurus plant, extraction and use of active ingredients thereof, for overcoming disadvantages of high residue, poor absorption, and less environmental friendliness of fertilizers used in cultivation of a selenium-rich plant in the prior art, and overcoming disadvantages of low absorption rate and high adverse reaction rate in current extraction method and application of active ingredients in a selenium-rich plant. The present invention provides a method of cultivating a selenium-rich Cyclocarya paliurus plant, comprising use of a selenium-rich organic fertilizer during the cultivation, wherein the selenium-rich organic fertilizer comprises a selenium-rich yeast, a humic acid, an amino acid, a plant growth regulator and a foliar penetration enhancer. The present invention also provides a method for extracting active ingredients of the selenium-rich Cyclocarya paliurus plant obtained by the above method, comprising pretreatment, extraction, concentration and alcohol precipitation to obtain a crude extract.

The present invention relates to cultivation of a selenium-rich Cyclocarya paliurus plant, extraction and use of active ingredients thereof, for overcoming disadvantages of high residue, poor absorption, and less environmental friendliness of fertilizers used in cultivation of a selenium-rich plant in the prior art, and overcoming disadvantages of low absorption rate and high adverse reaction rate in current extraction method and application of active ingredients in a selenium-rich plant. The present invention provides a method of cultivating a selenium-rich Cyclocarya paliurus plant, comprising use of a selenium-rich organic fertilizer during the cultivation, wherein the selenium-rich organic fertilizer comprises a selenium-rich yeast, a humic acid, an amino acid, a plant growth regulator and a foliar penetration enhancer. The present invention also provides a method for extracting active ingredients of the selenium-rich Cyclocarya paliurus plant obtained by the above method, comprising pretreatment, extraction, concentration and alcohol precipitation to obtain a crude extract.

A pharmaceutical composition composed of a dietary fiber composition composed of from about 48% to about 90% (w/w) glucomannan, from about 5% to about 20% (w/w) xanthan gum, and from about 5% to about 30% (w/w) alginate in combination with at least one of metformin or sitagliptin or a combination thereof is described. The pharmaceutical composition is effective to lower elevated blood glucose levels and total blood cholesterol levels in a subject significantly more than the dietary fiber composition alone or a composition consisting of at least one of metformin or sitagliptin or a combination thereof.

A method of treating hypercholesterolemia in mammals, by administering an effective amount of a microbial fermentation product, and regulating genes involved in lipoprotein metabolism. A method of regulating cholesterol levels in a patient by administering an effective amount of a composition chosen from the group consisting of PAZ, specific components isolated from PAZ, chemically synthesized analogues of the components of PAZ, and regulating genes involved in lipoprotein metabolism. A method of treating high cholesterol levels in an individual by administering an effective amount of a microbial fermentation product, up-regulating the expression of at least one of the genes that encode ABCA1, ApoA1, and SRB1, and down-regulating the gene that encodes CETP. A method of preventing the onset of high cholesterol levels and/or a deleterious lipoprotein profile in an individual.

A method of treating hypercholesterolemia in mammals, by administering an effective amount of a microbial fermentation product, and regulating genes involved in lipoprotein metabolism. A method of regulating cholesterol levels in a patient by administering an effective amount of a composition chosen from the group consisting of PAZ, specific components isolated from PAZ, chemically synthesized analogues of the components of PAZ, and regulating genes involved in lipoprotein metabolism. A method of treating high cholesterol levels in an individual by administering an effective amount of a microbial fermentation product, up-regulating the expression of at least one of the genes that encode ABCA1, ApoA1, and SRB1, and down-regulating the gene that encodes CETP. A method of preventing the onset of high cholesterol levels and/or a deleterious lipoprotein profile in an individual.

The present invention relates to a serum LDL cholesterol lowering edible product containing plant sterol ester and/or plant stanol ester, and especially to a dietary supplement product.

The present invention relates to a serum LDL cholesterol lowering edible product containing plant sterol ester and/or plant stanol ester, and especially to a dietary supplement product.

Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of nicotinic acid, nicotinamide riboside and/or nicotinic acid metabolites in combination with leucine and/or a leucine metabolite, with or without resveratrol.