A process for room temperature substrate bonding employs a first substrate substantially transparent to a laser wavelength is selected. A second substrate for mating at an interface with the first substrate is then selected. A transmissivity change at the interface is created and the first and second substrates are mated at the interface. The first substrate is then irradiated with a laser of the transparency wavelength substantially focused at the interface and a localized high temperature at the interface from energy supplied by the laser is created. The first and second substrates immediately adjacent the interface are softened with diffusion across the interface to fuse the substrates.

A method for producing a pneumatically actuatable microfluidic analysis cartridge includes closing a joining side of a fluidic part of the analysis cartridge with a first fluid-tight elastic membrane and/or closing a joining side of a pneumatic part of the analysis cartridge with a second membrane. The fluidic part is configured to perform fluidic basic operations of a biochemical analysis process, and the pneumatic part is configured to control the basic operations using air pressure. The joining side of the fluidic part and the joining side of the pneumatic part are aligned, and the fluidic part and the pneumatic part are connected to form the analysis cartridge.

A lens holder including a first portion made of a first plastic material capable of being laser welded to an imager assembly. The lens holder further includes a second portion made of a second plastic material capable of blocking infrared radiation. The first portion and the second portion are coupled together in nested relation.

A method of making a flowcell includes bonding a first surface of an organic solid support to a surface of a first inorganic solid support via a first bonding layer, wherein the organic solid support includes a plurality of elongated cutouts. The method further includes bonding a surface of a second inorganic solid support to a second surface of the organic solid support via a second bonding layer, so as to form the flowcell. The formed flowcell includes a plurality of channels defined by the surface of the first inorganic solid support, the surface of the second inorganic solid support, and walls of the elongated cutouts.

This invention provides a process and device for simultaneous laser welding; after using the moving lower die and the fixing upper die to make the base and the lens attached, by using the light pipe, for example, transparent substances or other cheap materials, to make the laser, which is emitted from the laser source, emit through the lens to a welding region of the base after being processed, to operate rapid and average heating to the welding region; meanwhile, using the welding cylinder to press the base and the lens together, to make base and the lens pressed and welded together in molten state, and when welding, it does not generate powder or other defects, and, at the same time, it can make the height H and the width w of the generated waste selvage between [0, 0.4] mm, which can improve the performance of welding object more efficiently.

Plastic parts are welded in a laser welding system. An infrared laser source in a laser chamber is controlled by a controller using closed-loop feedback control with a corrected feedback signal that is compensated for background infrared radiation in the laser chamber. Prior to the infrared laser source being turned on, the controller senses with the optical sensor an intensity of background infrared radiation in the laser chamber. Once the laser is on, the controller senses with the optical sensor an intensity of infrared laser radiation in the laser chamber. The controller calculates the corrected feedback signal by subtracting the intensity of the background infrared radiation sensed when the infrared laser source was off from the intensity of the infrared laser radiation sensed when the infrared laser source is on.

A manufacturing method is provided for a fluid control apparatus, in which the flow of a fluid is controlled by bringing a diaphragm valve element into contact with or separating the diaphragm valve element from a valve seat. The diaphragm valve element may be a joint body that is a combination of (a) a seat member that makes contact with the valve seat and (b) a body member. The joint body is formed by machining a material joint body obtained by welding together a seat-member material which is a material for the seat member and a body member material which is a material for the body member. The welding is performed on contact faces of the seat-member material and the body-member material of the material joint body in a range wider than contact faces of the seat member and the body member of the joint body.

The present disclosure relates to methods and components for the bonding together of plastic components during a manufacturing and/or assembly process to create molds for lost-wax casting.

A resin-junction body includes a first resin member, a second resin member including a concave portion and laminated on the first resin member so as to contact the first resin member at a contact surface. The concave portion comprises a bottom face on a first resin member side. The resin-junction body further includes a joining layer that joins the first resin member and the second resin member and that extends from the bottom face towards the first resin member.

A fluidic device including an inorganic solid support attached to an organic solid support by a bonding layer, wherein the inorganic solid support has a rigid structure and wherein the bonding layer includes a material that absorbs radiation at a wavelength that is transmitted by the inorganic solid support or the organic solid support; and a channel formed by the inorganic solid support and the organic solid support, wherein the bonding layer that attaches the inorganic solid support to the organic solid support provides a seal against liquid flow. Methods for making fluidic devices, such as this, are also provided.