The present invention relates to nutritional compositions comprising 2′-Fucosyllactose (2′FL) for use in improving the gastrointestinal barrier. In particular, the present invention relates to improving gastrointestinal barrier in an infant, a young child or children aged above 3 years to 8 years.

The present invention relates to nutritional compositions comprising 2′-Fucosyllactose (2′FL) for use in improving the gastrointestinal barrier. In particular, the present invention relates to improving gastrointestinal barrier in an infant, a young child or children aged above 3 years to 8 years.

Disclosed are methods and compositions comprising glycopeptides obtained from gastrointestinal sources that have superior microbiota effects. Such compositions are advantageous for food stuff, including infant formulations.

Disclosed are methods and compositions comprising glycopeptides obtained from gastrointestinal sources that have superior microbiota effects. Such compositions are advantageous for food stuff, including infant formulations.

The present invention relates to nutritional compositions comprising 2′-Fucosyllactose (2′FL), Di-fucosyllactose (Di-FL), Lacto-N-tetraose (LNT), Lacto-N-neotetraose (LNnT), 3′-Sialyllactose (3′SL) and 6′-Sialyllactose (6′SL) for use in improving gastrointestinal barrier. In particular, the present invention relates to improving the gastrointestinal barrier in an infant, a young child or children aged above 3 years to 8 years.

The present invention relates to nutritional compositions comprising 2′-Fucosyllactose (2′FL), Di-fucosyllactose (Di-FL), Lacto-N-tetraose (LNT), Lacto-N-neotetraose (LNnT), 3′-Sialyllactose (3′SL) and 6′-Sialyllactose (6′SL) for use in improving gastrointestinal barrier. In particular, the present invention relates to improving the gastrointestinal barrier in an infant, a young child or children aged above 3 years to 8 years.

The invention relates to the field of hypoallergenic oligosaccharides for use in nutritional compositions, in particular to oligosaccharides having prebiotic properties. Provided is a hypoallergenic oligosaccharide composition comprising galacto-oligosaccharides (GOS), wherein (i) the galacto-oligosaccharides (GOS) content is at least 40% by weight of the total dry matter of the composition; (ii) the allolactose content is at least 10% by weight of the total dry matter of the composition; (iii) the 6′-GL content is at least 30% by weight of the total GOS in the composition; and (iv) at least 0.5% by weight of the total GOS has a polymerization degree (DP) of six or more. The GOS composition does not trigger GOS-allergy as assessed in a basophil activation test (BAT).

The invention relates to the field of hypoallergenic oligosaccharides for use in nutritional compositions, in particular to oligosaccharides having prebiotic properties. Provided is a hypoallergenic oligosaccharide composition comprising galacto-oligosaccharides (GOS), wherein (i) the galacto-oligosaccharides (GOS) content is at least 40% by weight of the total dry matter of the composition; (ii) the allolactose content is at least 10% by weight of the total dry matter of the composition; (iii) the 6′-GL content is at least 30% by weight of the total GOS in the composition; and (iv) at least 0.5% by weight of the total GOS has a polymerization degree (DP) of six or more. The GOS composition does not trigger GOS-allergy as assessed in a basophil activation test (BAT).

Compositions comprising polysaccharides and oligosaccharides are provided. Methods for the formation of the compositions, including the enzymatic production of the oligosaccharides, and the uses of the compositions in foodstuffs, cosmetics, and nutraceuticals are also provided.

The invention relates to a nutritional composition comprising human milk oligosaccharide (HMO) having an effect on in a mammal to improve, enhance, promote or modulate a GABAergic function in the CNS, preferably in a human infant or a young children between birth and 7 years. The composition can be an infant formula. The HMO may be 2FL, diFL and/or LNT and or LNnT or combinations thereof.