This invention relates to the use of the combination of 25-hydroxyvitamin D3 (25-OH D3) and antioxidants/anti-inflammatories (ascorbic acid, vitamin E and at least one carotenoid) to make a pharmaceutical, nutraceutical or food supplement which can ameliorate various problems observed in humans connected with polycystic ovarian syndrome and cardiovascular diseases. Pharmaceuticals, nutraceuticals and food supplements containing the 25-OH D3 and antioxidants/anti-inflammatories and premixes are also provided.

The invention describes one or more compositions for causing an increase in thermogenesis in mammals, comprising at least caffeine, hordenine and -phenylethylamine and optionally the addition of B vitamins. The caffeine is often provided from green coffee bean extracts and normally comprises from 0.0001 g to 0.30 g of caffeine from 0.00001 g to 0.1 g of hordenine from barley and from 0.00001 g to 1.0 g -phenylethylamine from cocoa beans. The present invention finally provides a method that may cause a simultaneous and synergistic increase in central nervous system activity assisted by the addition of vitamin B as well as thermogenesis in mammals prior to physical exercise, the method comprising providing a composition comprising a source of caffeine, hordenine and -phenylethylamine.

The invention describes one or more compositions for causing an increase in thermogenesis in mammals, comprising at least caffeine, hordenine and -phenylethylamine and optionally the addition of B vitamins. The caffeine is often provided from green coffee bean extracts and normally comprises from 0.0001 g to 0.30 g of caffeine from 0.00001 g to 0.1 g of hordenine from barley and from 0.00001 g to 1.0 g -phenylethylamine from cocoa beans. The present invention finally provides a method that may cause a simultaneous and synergistic increase in central nervous system activity assisted by the addition of vitamin B as well as thermogenesis in mammals prior to physical exercise, the method comprising providing a composition comprising a source of caffeine, hordenine and -phenylethylamine.

Disclosed in the present specification is a composition comprising a Prunus mume flower extract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of IL-36G (NM 019618), which is a gene having an expression level affected by fine dust in skin cells, is regulated to a novel level. By using the composition for treating fine dust-caused skin damage, gene expression changed by fine dust can return to a normal level to treat skin cell damage.

Disclosed in the present specification is a composition comprising a Prunus mume flower extract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of IL-36G (NM 019618), which is a gene having an expression level affected by fine dust in skin cells, is regulated to a novel level. By using the composition for treating fine dust-caused skin damage, gene expression changed by fine dust can return to a normal level to treat skin cell damage.

The present invention relates to compositions and their uses, specifically provides supplements for equines, in particular horses and ponies. Such a composition is ideal for horses and ponies where promoting, supporting or maintaining calm behavior is desired or required.

The present invention relates to compositions and their uses, specifically provides supplements for equines, in particular horses and ponies. Such a composition is ideal for horses and ponies where promoting, supporting or maintaining calm behavior is desired or required.

What is disclosed is a protein supplement drink mix comprising at least one base protein powder and a plurality of separately packaged second components, each second component having at least one different active ingredient pre-selected for the physiological needs regarding a pre-determined activity, age, and/or gender demographic. The first component and the second component are mixed generally with a liquid to provide a base for a protein drink, although a liquid can form a portion of the first component or second components.

What is disclosed is a protein supplement drink mix comprising at least one base protein powder and a plurality of separately packaged second components, each second component having at least one different active ingredient pre-selected for the physiological needs regarding a pre-determined activity, age, and/or gender demographic. The first component and the second component are mixed generally with a liquid to provide a base for a protein drink, although a liquid can form a portion of the first component or second components.

The present invention relates to an antimicrobial composition comprising, as an active ingredient, 7,10-epoxyoctadeca-7,9-dienoic acid or a combination of 7,10-epoxyoctadeca-7,9-dienoic acid and another antibiotic. The growth of bacteria can be effectively inhibited regardless of the class of antibiotics when using the antimicrobial composition of the present invention. Therefore, the antimicrobial composition of the present invention can be useful in related pharmaceutical, food and cosmetic industries requiring the inhibition of bacterial growth.