A child resistant, zippered plastic bag assembly having a first side panel and a second side panel each having respective upper portions forming a mouth. The bag assembly includes a zippered closure coupled to the respective upper portions of the first and second side panels for interlocking the mouth between an opened condition and a closed condition. A slider having a base operably mounted to, and cooperating, with the zipper closure for movement between a first position, orienting the mouth in the closed condition, and a second position, orienting the mouth in the opened condition. The slider includes a first wing extending outwardly from the base, adjacent the upper portion of the first side panel, and a second wing also extending outwardly from the base, adjacent the upper portion of the second side panel. A lock is operable between the first wing and second wing, and configured to cooperate with the first side panel and the second side panel in a locked state to lock the slider in the first position.