The insert includes a base, the base including at least one depression that defines a cavity, the at least one depression including a floor with walls, the walls including a first pair of opposing walls and a second pair of opposing walls, the first pair of opposing walls each defining an undercut, the undercut including a lower inclined segment and an upper inclined segment that join at an apex, the apex of the undercut for each of the first pair of opposing walls facing each other, and a lid connected to an upper brim of the base, the lid covering the cavity.

A break-open single-dose sealed package and method for the production thereof; the sealed package has: a first sheet of semi-rigid plastic material; a second sheet of flexible plastic material set on top of and welded to the first sheet along an annular weld, so as to define a sealed pocket containing a dose of a product; and a pre-weakened area that develops transversely and is obtained in a central area of the first sheet; the pocket is divided into two distinct and separated chambers which are insulated from one another and each contain a corresponding component of the product; and the pocket is divided into the two chambers due to a central weld connecting the second sheet to the first sheet and is weak, so as to be broken by exerting pressure on at least one of the two chambers.

Described is a packaging, and method and system for packaging an individual and single serving of plant matter, such as a cannabis flower. Also described are a method of making and using for the packaging.

A PTP sheet for pharmaceutical drug packaging from which a solid pharmaceutical drug is easily taken out and in which a pocket portion is hard to be accidentally damaged. A PTP sheet has a first sheet from which a pocket portion capable of housing a solid pharmaceutical drug protrudes to the side of an upper surface and a second sheet which is stuck to a lower surface of the first sheet and which closes an opening of the pocket portion. The pocket portion has a peripheral wall portion having a peripheral surface continuous with the upper surface and a top portion having a top surface continuous with the peripheral surface of the peripheral wall portion. A wall thickness of the peripheral wall portion is smaller than a wall thickness of the top portion.

A cover sheet for a multi-compartment package for dispensing plural items is disclosed. The package includes plural individual sealed compartment units which are releasably secured to each other. Each compartment unit includes a flanged base from which a chamber depends. The chamber holds an item to be dispensed and is surrounded by a flange. The cover sheet, includes respective closure members releasably secured to each other by frangible lines. Each closure member is configured to be adhesively secured to the flange of each compartment unit. Each closure member includes plural arcuate tamper-evident cuts therein located adjacent respective corners of the closure member to initiate a tear upon attempted removal of the closure member from the flange of its associated compartment unit.

A cover sheet for a multi-compartment package for dispensing plural items is disclosed. The package includes plural individual sealed compartment units which are releasably secured to each other. Each compartment unit includes a flanged base from which a chamber depends. The chamber holds an item to be dispensed and is surrounded by a flange. The cover sheet, includes respective closure members releasably secured to each other by frangible lines. Each closure member is configured to be adhesively secured to the flange of each compartment unit. Each closure member includes plural arcuate tamper-evident cuts therein located adjacent respective corners of the closure member to initiate a tear upon attempted removal of the closure member from the flange of its associated compartment unit.

A method of manufacturing a PTP sheet for pharmaceutical drug packaging from which a solid pharmaceutical drug is easily taken out and in which a pocket portion is hard to be accidentally damaged. The PTP sheet has a first sheet from which a pocket portion capable of housing a solid pharmaceutical drug protrudes to the side of an upper surface and a second sheet which is stuck to a lower surface of the first sheet and which closes an opening of the pocket portion. The pocket portion has a peripheral wall portion having a peripheral surface continuous with the upper surface and a top portion having a top surface continuous with the peripheral surface of the peripheral wall portion. A wall thickness of the peripheral wall portion is smaller than a wall thickness of the top portion.

A cover sheet for a multi-compartment package for dispensing plural items is disclosed. The package includes plural individual sealed compartment units which are releasably secured to each other. Each compartment unit includes a flanged base from which a chamber depends. The chamber holds an item to be dispensed and is surrounded by a flange. The cover sheet, includes respective closure members releasably secured to each other by frangible lines. Each closure member is configured to be adhesively secured to the flange of each compartment unit. Each closure member includes plural arcuate tamper-evident cuts therein located adjacent respective corners of the closure member to initiate a tear upon attempted removal of the closure member from the flange of its associated compartment unit.

The technical result of the invention is structurally creation of a biotechnical system of common blister pack elements consistently providing the drug substance with excellent ways of delivering a solid therapeutic dose orally or a liquid subtherapeutic dose sublingually.

The combination of individual separate delivery routes for solid therapeutic dose orally or a subtherapeutic liquid dose sublingually is a qualitatively new structural pharmacotherapy unit enabling the postadaptation hormesis effect. The advantage of the new drug form is elimination of the pre-systemic metabolism effect in liver with a subtherapeutic dose along with systemic bioavailability enhancement, prevention of drug destruction by chlorobutanol acid in the stomach and by alkaline contents in the intestines, and body resistance improvement.

The invention relates to novel child-resistant blister card packages for medicaments. The blister card package comprises a rigid container sheet with cavities for containing a medicament and a cover sheet sealed to the container sheet and covering the cavities. The blister card package is detachable into individual sections or units, along lines of perforations. Each individual blister packing unit comprises a tear tab, a fold tab and at least one crease tab. The user operates three-step opening process, namely, tear-fold-tear, to open and access the medicament from the individual blister unit.