Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating biofilms in or on tissue, including biofilms related to wounds or other skin trauma. The compositions are useful for treating a variety of types of tissue, both on the surface on beneath the surface of tissue. Compositions are provided having various concentrations for different tissue types and infection levels. Compositions may be provided in gel form, and may include nanoparticle encapsulated molecules for controlled release.

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating biofilms in or on tissue, including biofilms related to wounds or other skin trauma. The compositions are useful for treating a variety of types of tissue, both on the surface on beneath the surface of tissue. Compositions are provided having various concentrations for different tissue types and infection levels. Compositions may be provided in gel form, and may include nanoparticle encapsulated molecules for controlled release.

A system to prepare an antimicrobial solution by the electrolysis of brine is presented where the antimicrobial solution is a solution comprising HOCl that contains a HOCl concentration in excess of 500 ppm or more at a pH of 6 to 6.8 with a low residual salt concentration and displays a stability in excess of 60 days and can have a HOCl concentration in excess of 450 for 180 days. The system includes an electrolysis cell that is improved by a superior anode and ceramic membrane such that when employed with a DC power supply controlled by a microprocessor and a controlled brine concentration provided to the cell at ambient temperature at a controlled rate, delivers a fluid that is continuously monitored by a pH probe and an ORP probe for input to the microprocessor.

A system to prepare an antimicrobial solution by the electrolysis of brine is presented where the antimicrobial solution is a solution comprising HOCl that contains a HOCl concentration in excess of 500 ppm or more at a pH of 6 to 6.8 with a low residual salt concentration and displays a stability in excess of 60 days and can have a HOCl concentration in excess of 450 for 180 days. The system includes an electrolysis cell that is improved by a superior anode and ceramic membrane such that when employed with a DC power supply controlled by a microprocessor and a controlled brine concentration provided to the cell at ambient temperature at a controlled rate, delivers a fluid that is continuously monitored by a pH probe and an ORP probe for input to the microprocessor.

A method is provided for filling a bag-on-valve can with a hypochlorous acid solution, including: providing a hypochlorous acid manufacturing apparatus having an anolyte storage tank in which the hypochlorous acid solution is stored; providing a bag-on-valve canning apparatus having a fluid inlet; connecting a pipe between the anolyte storage tank of the hypochlorous acid manufacturing apparatus and the fluid inlet on the bag-on-valve canning apparatus in order to provide the hypochlorous acid solution directly from the hypochlorous acid manufacturing apparatus to the bag-on-valve canning apparatus; providing a bag-on-valve can having a can in which a bag and a valve are disposed, wherein the valve seals the bag during non-use, the bag-on-valve can further including an actuator for actuating the valve; and filling the bag with the hypochlorous acid solution provided through the pipe. An apparatus is also disclosed for producing and canning a hypochlorous acid solution.

A method is provided for filling a bag-on-valve can with a hypochlorous acid solution, including: providing a hypochlorous acid manufacturing apparatus having an anolyte storage tank in which the hypochlorous acid solution is stored; providing a bag-on-valve canning apparatus having a fluid inlet; connecting a pipe between the anolyte storage tank of the hypochlorous acid manufacturing apparatus and the fluid inlet on the bag-on-valve canning apparatus in order to provide the hypochlorous acid solution directly from the hypochlorous acid manufacturing apparatus to the bag-on-valve canning apparatus; providing a bag-on-valve can having a can in which a bag and a valve are disposed, wherein the valve seals the bag during non-use, the bag-on-valve can further including an actuator for actuating the valve; and filling the bag with the hypochlorous acid solution provided through the pipe. An apparatus is also disclosed for producing and canning a hypochlorous acid solution.

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating transient biofilms in or on tissue without harming the natural flora of the tissue. The compositions are useful for treating a variety of types of tissue. Compositions are useful for treating and preventing orally-associated biofilm. Compositions may be provided in mouthwash form, spray form, gel form, cream form, dentifrice form, and may include nanoparticle encapsulated molecules for controlled release.

Disinfecting compositions containing hypochlorous acid and acetic acid are useful for treating transient biofilms in or on tissue without harming the natural flora of the tissue. The compositions are useful for treating a variety of types of tissue. Compositions are useful for treating and preventing orally-associated biofilm. Compositions may be provided in mouthwash form, spray form, gel form, cream form, dentifrice form, and may include nanoparticle encapsulated molecules for controlled release.

The present invention provides a stabilized hypohalous acid solution (or formulation thereof), which may be conveniently packaged for sale, or stored for later use on demand. The invention further provides methods of making the stabilized hypohalous acid solution, as well as methods of use for disinfecting mammalian tissue, including wounds and burns, disinfecting or cleansing surfaces, or treating and/or preserving food products and cut flowers, among other uses.

The present invention provides a stabilized hypohalous acid solution (or formulation thereof), which may be conveniently packaged for sale, or stored for later use on demand. The invention further provides methods of making the stabilized hypohalous acid solution, as well as methods of use for disinfecting mammalian tissue, including wounds and burns, disinfecting or cleansing surfaces, or treating and/or preserving food products and cut flowers, among other uses.