A glass container comprises a glass body comprising a first region under a compressive stress extending from a surface of the glass body to a depth of compression and a second region extending from the depth of compression into a thickness of the glass body, the second region being under a tensile stress. The glass container also includes a localized compressive stress region having a localized compressive stress extending from the surface to a localized depth of compression within the body. The localized depth of compression is greater than the depth of compression of the first region. The glass container also includes a crack re-direction region extending in a predetermined propagation direction, wherein the crack re-direction region possesses a higher tensile stress than the tensile stress in the second region in a sub-region of the crack re-direction region, the sub-region extending substantially perpendicular to the predetermined propagation direction.

A glass tube semi-finished product or a hollow glass product manufactured from the glass tube semi-finished product is provided with a first marking with information on the origin and/or tube-specific production data of the glass tube semi-finished product, which marking is read from the hollow glass product after its manufacture to determine the origin and/or the tube-specific production data of the glass tube semi-finished product, e.g., to identify the semi-finished glass tube from which the hollow glass product has been made, and/or trace the tube-specific production data of this glass tube semi-finished product. This means that the entire supply chain for the hollow glass product from the supplier of the originally used glass tube semi-finished product up to the end product can be determined. The physical and chemical characteristics of the glass tube semi-finished product are not altered for producing the first marking.

A glass tube semi-finished product or a hollow glass product manufactured from the glass tube semi-finished product is provided with a first marking with information on the origin and/or tube-specific production data of the glass tube semi-finished product, which marking is read from the hollow glass product after its manufacture to determine the origin and/or the tube-specific production data of the glass tube semi-finished product, e.g., to identify the semi-finished glass tube from which the hollow glass product has been made, and/or trace the tube-specific production data of this glass tube semi-finished product. This means that the entire supply chain for the hollow glass product from the supplier of the originally used glass tube semi-finished product up to the end product can be determined. The physical and chemical characteristics of the glass tube semi-finished product are not altered for producing the first marking.

A glass container comprises a glass body comprising a first region under a compressive stress extending from a surface of the glass body to a depth of compression and a second region extending from the depth of compression into a thickness of the glass body, the second region being under a tensile stress. The glass container also includes a localized compressive stress region having a localized compressive stress extending from the surface to a localized depth of compression within the body. The localized depth of compression is greater than the depth of compression of the first region. The glass container also includes a crack re-direction region extending in a predetermined propagation direction, wherein the crack re-direction region possesses a higher tensile stress than the tensile stress in the second region in a sub-region of the crack re-direction region, the sub-region extending substantially perpendicular to the predetermined propagation direction.

A glass container comprises a glass body comprising a first region under a compressive stress extending from a surface of the glass body to a depth of compression and a second region extending from the depth of compression into a thickness of the glass body, the second region being under a tensile stress. The glass container also includes a localized compressive stress region having a localized compressive stress extending from the surface to a localized depth of compression within the body. The localized depth of compression is greater than the depth of compression of the first region. The glass container also includes a crack re-direction region extending in a predetermined propagation direction, wherein the crack re-direction region possesses a higher tensile stress than the tensile stress in the second region in a sub-region of the crack re-direction region, the sub-region extending substantially perpendicular to the predetermined propagation direction.

A glass tube element having a hollow cylindrical section with a shell having an outer diameter is provided. A first ratio is a difference value to a mean value. The difference value is a difference of a minimal and maximal value of the outer diameter. The mean value is a mean of the minimal and maximal values. A sub-section having a start, an end, and a distance of 1 meter measured along a straight line from the start to the end and intersecting with a center axis of the sub-section at the start and the end. The sub-section having, for every point of the center axis, a shortest distance to the straight line. A second ratio of a specific distance to 1 meter, the specific distance being defined as a largest of all shortest distances. A product of the first and second ratio is smaller than 4×10.sup.−6.

A synthetic quartz glass substrate having a controlled hydrogen molecule concentration is prepared by (a) hot shaping a synthetic quartz glass ingot into a glass block, (b) slicing the glass block into a glass plate, (c) annealing the glass plate at 500-1,250 C. for 15-60 hours, (d) hydrogen doping treatment of the glass plate in a hydrogen gas atmosphere at 300-450 C. for 20-40 hours, and (e) dehydrogenation treatment of the glass plate at 200-400 C. for 5-10 hours.

A synthetic quartz glass substrate having a controlled hydrogen molecule concentration is prepared by (a) hot shaping a synthetic quartz glass ingot into a glass block, (b) slicing the glass block into a glass plate, (c) annealing the glass plate at 500-1,250 C. for 15-60 hours, (d) hydrogen doping treatment of the glass plate in a hydrogen gas atmosphere at 300-450 C. for 20-40 hours, and (e) dehydrogenation treatment of the glass plate at 200-400 C. for 5-10 hours.

A glass container for storing pharmaceutical formulations may include a glass body formed from a Type IA or Type IB glass composition according to ASTM Standard E438-92(2011). The glass body may include a wall portion with an inner surface and an outer surface, a heel portion and a floor portion, wherein the inner surface of the glass container is formed by the inner surface of the glass body. The glass body may include at least a class A2 base resistance or better according to ISO 695, at least a type HGB2 hydrolytic resistance or better according to ISO 719 and Type 1 chemical durability according to USP <660>. The glass container does not comprise a boron-rich layer on the inner surface of the glass body in as formed condition.

A glass container for storing pharmaceutical formulations may include a glass body formed from a Type IA or Type IB glass composition according to ASTM Standard E438-92(2011). The glass body may include a wall portion with an inner surface and an outer surface, a heel portion and a floor portion, wherein the inner surface of the glass container is formed by the inner surface of the glass body. The glass body may include at least a class A2 base resistance or better according to ISO 695, at least a type HGB2 hydrolytic resistance or better according to ISO 719 and Type 1 chemical durability according to USP <660>. The glass container does not comprise a boron-rich layer on the inner surface of the glass body in as formed condition.