An antimicrobial ceramic glazing composition contains one or more antimicrobial agents disposed therein. Methods for making and using the glazing composition are disclosed, as well as substrates having a fired antimicrobial glaze thereon. The antimicrobial agents comprise metallic oxides, with a subset of the disclosed combinations exhibiting synergistic effect in fired glazes.

An antimicrobial ceramic glazing composition contains one or more antimicrobial agents disposed therein. Methods for making and using the glazing composition are disclosed, as well as substrates having a fired antimicrobial glaze thereon. The antimicrobial agents comprise metallic oxides, with a subset of the disclosed combinations exhibiting synergistic effect in fired glazes.

An antimicrobial ceramic glazing composition contains one or more antimicrobial agents disposed therein. Methods for making and using the glazing composition are disclosed, as well as substrates having a fired antimicrobial glaze thereon. The antimicrobial agents comprise metallic oxides, with a subset of the disclosed combinations exhibiting synergistic effect in fired glazes.

Embodiments of the present invention pertain to antimicrobial glass compositions, glasses and articles. The articles include a glass, which may include a glass phase and a cuprite phase. In other embodiments, the glasses include as plurality of Cu.sup.1+ ions, a degradable phase including B2O3, P.sub.2O.sub.5 and K.sub.2O and a durable phase including SiO.sub.2. Other embodiments include glasses having a plurality of Cu.sup.1+ ions disposed on the surface of the glass and in the glass network and/or the glass matrix. The article may also include a polymer. The glasses and articles disclosed herein exhibit a 2 log reduction or greater in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus, and E. coli, under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing condition and under Modified JIS Z 2801 for Bacteria testing conditions.

The present invention is directed to a kind of machinable glass ceramic which can be chemically toughened. The machinable and chemically toughenable glass ceramic, which comprises, as represented by weight percentage based on the following compositions, 25-75 wt % of SiO.sub.2, 6-30 wt % of Al.sub.2O.sub.3, 0.1-30 wt % of Na.sub.2O, 0-15 wt % of K.sub.2O, 0-30 wt % of B.sub.2O.sub.3, 4-35 wt % of MgO, 0-4 wt % of CaO, 1-20 wt % of F, 0-10 wt % of ZrO.sub.2, 0.1-10 wt % of P.sub.2O.sub.5, 0-1 wt % of CeO.sub.2 and 0-1 wt % of SnO.sub.2, wherein P.sub.2O.sub.5+Na.sub.2O>3 wt %, and Al.sub.2O.sub.3+Na.sub.2O+P.sub.2O.sub.5>17 wt %. Mica crystalline phase can be formed in the glass ceramic and the glass ceramic can be chemically toughened by one step, two steps or multiple steps with depth of K-ion layer of at least 15 m and surface compress stress of at least 300 MPa. The profile on depth of the ion exchange layer follows the complementary error function. Hardness can be improved by at least 20% after chemical toughening. The dimension deviation ratio is less than 0.06% by ion-exchanging.

A strengthened antimicrobial glass including greater from about 50.0 mol. % to about 65.0 mol. % SiO.sub.2, about 14.0 mol. % to about 22.0 mol. % Al.sub.2O.sub.3, about 14.0 mol. % to about 22.0 mol. % R.sub.2O, wherein R is an alkali metal, and about 4.0 mol. % to 10.0 mol. % P.sub.2O.sub.5. The glass may have a compressive stress layer having a thickness of greater than or equal to about 20 m less than or equal to about 60 m and having a compressive stress of greater than or equal to about 700 MPa. The glass may have an antimicrobial activity greater than or equal to about 1.0 log kill at about 23 C. and about 40.0% relative humidity. A method for making the glass may include obtaining a glass article, strengthening the glass article by contact with a first ion-exchange liquid, and contacting the glass article with second ion-exchange liquid comprising an antimicrobial agent.

Described herein are various antimicrobial soda lime glass articles that have improved resistance to discoloration when exposed to harsh conditions, including manufacturing conditions. The improved antimicrobial glass articles described herein generally include a SLG substrate that has a thickness, t; a compressive stress layer of about 0.15*t or greater; and an antimicrobial agent-containing region having an antimicrobial agent and a thickness less than the thickness of the compressive stress layer. Roughly 2 to 20 microns of the primary surfaces of the glass substrate can be removed prior to development of the compressive stress and antimicrobial agent-containing region. In some aspects, prior-annealed and tempered, or prior-annealed, SLG is employed as the substrate. In some aspects, the substrate includes tin at one surface. The improved SLG substrates experience substantially no discoloration when exposed to harsh conditions. Methods of making and using the glass articles are also described.

A method of making an antimicrobial glass article that includes the steps: submersing the article in a strengthening bath to exchange a portion of ion-exchangeable metal ions in the glass article with a portion of ion-exchanging metal ions in the strengthening bath to form a compressive stress layer extending from the first surface to a diffusion depth in the article; removing a portion of the compressive stress layer from the first surface of the article to a first depth above the diffusion depth in the article to define a new first surface and a remaining compressive stress layer; and submersing the article in an antimicrobial bath to exchange a portion of the ion-exchangeable and the ion-exchanging metal ions in the compressive stress layer with a portion of the silver metal ions in the antimicrobial bath to impart an antimicrobial property in the article.

A method of making a glass having antimicrobial properties and high compressive stress. The method includes a first ion exchange step in which potassium cations are exchanged for sodium cations in the base glass to provide a surface layer under compressive stress, followed by a second ion exchange in which silver cations are exchanged for potassium and lithium ions in the glass to produce the antimicrobial glass. In some embodiments, the antimicrobial glass has a maximum compressive stress that is at least 80% of the maximum compressive stress obtained by the potassium-for-sodium exchange in the first bath. A base glass and an ion exchanged glass antimicrobial having antimicrobial properties are also provided.

An antibacterial composition, includes: a borate-based glass material having a composition of: 0-25 wt. % SiO.sub.2, 30-75 wt. % B.sub.2O.sub.3, 0-10 wt. % P.sub.2O.sub.5, 0-30 wt. % Al.sub.2O.sub.3, 0-5 wt. % Li.sub.2O, 1-25 wt. % Na.sub.2O, 0-15 wt. % K.sub.2O, 0-10 wt. % MgO, 10-25 wt. % CaO, 12-30 wt. % MO, 8-25 wt. % R.sub.2O, and 30-75 (B.sub.2O.sub.3+Al.sub.2O.sub.3), such that at least one of P.sub.2O.sub.5 or Al.sub.2O.sub.3 is present, MO is the sum of MgO, CaO, SrO, and BaO, R.sub.2O is the sum of Na.sub.2O, K.sub.2O, Li.sub.2O, and Rb.sub.2O, and the borate-based glass material is configured to achieve at least a 3.5-log kill rate of at least one of E. coli, P. gingivalis, or S. mutans bacteria.