The present invention relates to inorganic fibres having a composition comprising: 65.7 to 70.8 wt % SiO.sub.2; 27.0 to 34.2 wt % CaO; 0.10 to 2.0 wt % MgO; and optional other components providing the balance up to 100 wt %,
wherein the sum of SiO.sub.2 and CaO is greater than or equal to 97.8 wt %; and the other components, when present, comprise no more than 0.80 wt % Al.sub.2O.sub.3; and wherein the amount of MgO and other components are configured to inhibit the formation of surface crystallite grains upon heat treatment at 1100° C. for 24 hours, wherein said surface crystallite grains comprise an average crystallite size in a range of from 0.0 to 0.90 μm.

A process for the manufacture of inorganic fibres comprises: (a) selecting a composition and proportion of: (i) silica sand; (ii) lime comprising at least 0.10 wt % magnesia; and (iii) optional additives comprising a source of oxides or non-oxides of one or more of the lanthanides series of elements, or combinations thereof; (b) mixing the silica sand; lime; and optional additives to form a mixture; (c) melting the mixture in a furnace; and (d) shaping the molten mixture into inorganic fibres. The raw materials selection comprises composition selection and proportion selection of the raw materials to obtain an inorganic fibre composition comprising a range of from 61.0 wt % and 70.8 wt % silica; less than 2.0 wt % magnesia; less than 2.0% incidental impurities; and no more than 2.0 wt % of metal oxides and/or metal non-oxides derived from said optional additives; with calcia providing the balance up to 100 wt %; and wherein the inorganic fibre composition comprises no more than 0.80 wt % Al.sub.20.sub.3 derived from the incidental impurities and/or the optional additives.

The present invention provides a biological glass fiber for regenerative medical materials, comprising a biological glass or a biologically-inert glass made of a glass chemical composition. The glass chemical composition comprises in weight percentage, 5 to 25 wt% Na.sub.2O, 45 to 67 wt% SiO.sub.2, 15 to 25 wt% CaO, 2 to 6 wt% P.sub.2O.sub.5, 1 to 8 wt% MgO, 8 to 12.5 wt% K.sub.2O, 0.1 to 5 wt% total combined of non-toxic elements found in Group 5 and non-toxic elements found in Transition Metal Groups 3B, 4B and 5B, based on 100 wt% of the glass chemical composition; wherein the biological glass fiber forms a fiber configuration. The biological glass fiber is a soluble, resorbable, light transmittable and controllable absorption time regenerative material, and the biological glass fiber can mediate: therapeutic lymphangiogenesis, stem cell regeneration, bone cell regeneration and neurovascular regeneration, or it can be used as a cell carrier.

The disclosure relates to bioactive glasses for use in biomedical applications. In particular, the glasses described herein are phosphate glasses that show fast filling rates of dentin tubules and have advantageous release rates of metal ions, which provide advantages in antibacterial applications and wound healing.

The present invention relates to inorganic fibres having a composition comprising: 61.0 to 70.8 wt % SiO.sub.2; 28.0 to 39.0 wt % CaO; 0.10 to 0.85 wt % MgO other components, if any, providing the balance up to 100 wt %, The sum of SiO.sub.2 and CaO is greater than or equal to 98.8 wt % and the other components comprise less than 0.70 wt % Al.sub.2O.sub.3, if any.

Methods of making a bioactive glass fiber include forming a melt of a glass composition including: 50 to 70% SiO.sub.2; 0.1 to 10% Al.sub.2O.sub.3, 5 to 30% Na.sub.2O, 0.1 to 15% K.sub.2O, 0.1 to 15% MgO, 0.1 to 20% CaO, and 5 to 10% P.sub.2O.sub.5, based on a 100 wt % of the glass composition. The melt has a viscosity of from 200 Poise to 2,000 Poise. Methods include drawing the melt into a drawn glass fiber. Bioactive glass compositions include: 60 to 70% SiO.sub.2; 15 to 30% Na.sub.2O, 5 to 15% K.sub.2O, 1 to 10% CaO, and 5 to 10% P.sub.2O.sub.5, based on a 100 wt % of the glass composition.

A silicate-based glass composition includes: 40-60 wt. % SiO.sub.2, 0-10 wt. % B.sub.2O.sub.3, 0.01-10 wt. % P.sub.2O.sub.5, 0-10 wt. % Al.sub.2O.sub.3, 0-5 wt. % Li.sub.2O, 10-30 wt. % Na.sub.2O, 0.01-15 wt. % K.sub.2O, 0.01-5 wt. % MgO, 15-30 wt. % CaO, 15-35 wt. % MO, and 15-30 wt. % R.sub.2O, such that MO is the sum of MgO, CaO, SrO, BeO, and BaO, and R.sub.2O is the sum of Na.sub.2O, K.sub.2O, Li.sub.2O, Rb.sub.2O, and Cs.sub.2O.

A bioactive glass composition including: 50 to 70% SiO.sub.2; 0.1 to 10% Al.sub.2O.sub.3, 5 to 30% Na.sub.2O, 0.1 to 15% K.sub.2O, 0.1 to 15% MgO, 0.1 to 20% CaO, and 5 to 10% P.sub.2O.sub.5, based on a 100 wt % of the composition. Also disclosed is a method of making the bioactive glass composition.

The present invention relates to inorganic fibres having a composition comprising: 61.0 to 70.8 wt% SiO.sub.2; 28.0 to 39.0 wt% CaO; 0.10 to 0.85 wt% MgO other components, if any, providing the balance up to 100 wt %,

The sum of SiO.sub.2 and CaO is greater than or equal to 98.8 wt % and the other components comprise less than 0.70 wt % Al.sub.2O.sub.3, if any.

An inorganic fiber containing silica, alumina, one or more alkali metal oxides, and one or more of alkaline earth metal oxides, transition metal oxides, or lanthanide series metal oxides. The inorganic fiber exhibits good thermal performance at use temperatures of 1260° C. and greater, retains mechanical integrity after exposure to the use temperatures, is free of crystalline silica upon devitrification, is alkali flux resistant, exhibits low bio-persistence in an acidic medium, and exhibits low dissolution in a neutral medium. Also provided are thermal insulation products incorporating the inorganic fibers, a method for preparing the inorganic fiber and a method of thermally insulating articles using thermal insulation prepared from the inorganic fibers.