The present invention provides a process for preparing a diester compound of the following general formula (1), having a dimethylcyclobutane ring, wherein R.sup.1 and R.sup.2 represent, independently of each other, a monovalent hydrocarbon group having 1 to 10 carbon atoms, the process comprising reacting a dimethylcyclobutanone compound of the following general formula (2), wherein R.sup.1 is as defined above, with a phosphonic ester compound of the following general formula (3), wherein R.sup.2 and R.sup.3 represent, independently of each other, a monovalent hydrocarbon group having 1 to 10 carbon atoms, to produce the diester compound (1), having a dimethylcyclobutane ring.

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The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.

The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.

The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.

The present invention relates to a cost-effective and efficient method for preparing treprostinil with high purity, and an intermediate therefor.

The present invention relates to a cost-effective and efficient method for preparing treprostinil with high purity, and an intermediate therefor.

Provided are processes for preparing alpha, beta-unsaturated functional compounds using four major reaction steps: 1) air oxidation of an iso-paraffin to a mixture of alkyl hydroperoxide and alcohol; 2) converting the alkyl hydroperoxide and alcohol to dialkyl peroxide; 3) oxidative cross-coupling between a primary or secondary alcohol and a compound comprising at least one R3CH2- (R3=hydrogen or an optionally substituted hydrocarbyl) moiety to afford a coupled product using the dialkyl peroxide as a radical initiator, while the dialkyl peroxide is converted to a tertiary alcohol; 4) dehydration of the coupled product to yield an alpha, beta-unsaturated functional compound.

Provided are processes for preparing alpha, beta-unsaturated functional compounds using four major reaction steps: 1) air oxidation of an iso-paraffin to a mixture of alkyl hydroperoxide and alcohol; 2) converting the alkyl hydroperoxide and alcohol to dialkyl peroxide; 3) oxidative cross-coupling between a primary or secondary alcohol and a compound comprising at least one R3CH2- (R3=hydrogen or an optionally substituted hydrocarbyl) moiety to afford a coupled product using the dialkyl peroxide as a radical initiator, while the dialkyl peroxide is converted to a tertiary alcohol; 4) dehydration of the coupled product to yield an alpha, beta-unsaturated functional compound.

Disclosed is a method of: providing a fiber having propylene oxide adsorbed thereon; exposing the fiber to a gaseous sample; allowing the propylene oxide to react with any chlorine in the sample to form chloro-2-propanol. The method can be used to detect potassium chlorate.

Disclosed is a method of: providing a fiber having propylene oxide adsorbed thereon; exposing the fiber to a gaseous sample; allowing the propylene oxide to react with any chlorine in the sample to form chloro-2-propanol. The method can be used to detect potassium chlorate.