The present invention concerns a method for synthesizing cyclohexenone and cyclohexenol compounds having specific fragrances and remanence properties, said method consisting in condensing a ketone on an -methylene-aldehyde in order to obtain, by means of a domino reaction, compounds of formula (I). ##STR00001##

The present invention concerns a method for synthesizing cyclohexenone and cyclohexenol compounds having specific fragrances and remanence properties, said method consisting in condensing a ketone on an -methylene-aldehyde in order to obtain, by means of a domino reaction, compounds of formula (I). ##STR00001##

The present invention pertains to novel cyclopentanols and their unexpected advantageous use thereof in enhancing, improving or modifying the fragrance of perfumes, colognes, toilet waters, fabric care products, personal products, and the like.

The present invention pertains to novel cyclopentanols and their unexpected advantageous use thereof in enhancing, improving or modifying the fragrance of perfumes, colognes, toilet waters, fabric care products, personal products, and the like.

Disclosed are 2-methylene analogs of vitamin D.sub.3 and related compounds, their biological activities, and various pharmaceutical uses for these analogs. Particularly disclosed are 1-hydroxy-2-methylene-vitamin D.sub.3, (20S)-1-hydroxy-2-methylene-vitamin D.sub.3, and (5E)-1,25-dihydroxy-2-methylene-vitamin D.sub.3, their biological activities, and various pharmaceutical uses for these compounds including methods of treating and/or preventing bone diseases and disorders.

Disclosed are 2-methylene analogs of vitamin D.sub.3 and related compounds, their biological activities, and various pharmaceutical uses for these analogs. Particularly disclosed are 1-hydroxy-2-methylene-vitamin D.sub.3, (20S)-1-hydroxy-2-methylene-vitamin D.sub.3, and (5E)-1,25-dihydroxy-2-methylene-vitamin D.sub.3, their biological activities, and various pharmaceutical uses for these compounds including methods of treating and/or preventing bone diseases and disorders.

Cyclohexenone and cyclohexenol compounds are provided having specific fragrances and remanence properties, along with methods for synthesizing these compounds, including obtaining the compound by condensing a ketone on an -methylene-aldehyde in order to obtain, by means of a domino reaction, compounds of formula (II) as follows:

##STR00001##

Cyclohexenone and cyclohexenol compounds are provided having specific fragrances and remanence properties, along with methods for synthesizing these compounds, including obtaining the compound by condensing a ketone on an -methylene-aldehyde in order to obtain, by means of a domino reaction, compounds of formula (II) as follows:

##STR00001##

The various aspects presented herein relate to the perfumery industry. More particularly, the various aspects presented herein relate to malodor counteracting compositions and/or ingredients, methods for counteracting malodors, as well as to the perfumed articles or perfuming compositions comprising as an active ingredient, at least one compound selected from the group consisting of: a compound of Formula (I), a compound of Formula (II), a compound of Formula (III), a compound of Formula (IV), and mixtures thereof.

The present invention relates to compounds of pharmaceutical interest. More particularly, it relates to compounds of formula (I), to processes for obtaining thereof, to the intermediates of their synthesis and processes for obtaining the latter. The compounds of formula (I) have a certain affinity with the vitamin D receptor, they are active in a similar order to 1,25-dihydroxyvitamin D.sub.3 (1,25D), with the advantage of producing less or no hypercalcemia.