Essential oils, such as CBD oil, are extracted from biomass, such as hemp, in a continuous process. The biomass is delivered to the upper end of a vertically oriented extraction chamber, while a solvent is injected at the lower end thereof. As the solvent flows upwardly, the oil is removed from the biomass. The resulting liquor is collected and purified.

The invention relates to methods for producing botanical extracts comprising cannabinoids and terpenes using cold extraction with highly polyunsaturated lipid solvents. These methods allow for the extraction of cannabinoids and terpenes while leaving behind impurities that are commonly found in organic solvent extraction methods.

The invention relates to methods for producing botanical extracts comprising cannabinoids and terpenes using cold extraction with highly polyunsaturated lipid solvents. These methods allow for the extraction of cannabinoids and terpenes while leaving behind impurities that are commonly found in organic solvent extraction methods.

A method of generating an oligosaccharide encapsulated cannabidiol (CBD) formulation includes forming a cannabidiol ethanol mixture comprising ethanol and cannabidiol, forming an oligosaccharide CBD slurry by mixing the oligosaccharide with the cannabidiol ethanol mixture. The slurry is heated and mixed in a pressurized chamber to form a colloidal mixture, which is distributed into a tray as a layer. A cover is added to the tray to form an evaporation vessel, which is heated in a heating chamber. A rapid cooling process is performed on the colloidal mixture layer by removing the cover and spraying pulverized dry ice on the layer. The rapid cooling process is repeated until crystal formation is detected within the layer, the crystals including oligosaccharide encapsulated cannabidiol. An oligosaccharide encapsulated cannabidiol formulation includes cannabidiol and at least one oligosaccharide in a ratio in the range between about 1000:1 to 2200:1 (w/w) of CBD.

Methods for extracting and concentrating cannabinoids using ultrasound-enhanced solvent extraction. Freshly harvested cannabis plant materials, which may be selectively chosen plant parts or the entire plant itself, are shredded to a particular particle size. The plant material is then mixed with a solvent to form a slurry, and thereafter subjected to ultrasound to release intracellular contents into the solvent. Filtering steps are then applied to remove biomass, waxes and chlorophyll. Water removal and solvent recovery steps are further applied to ultimately derive an extract having high concentrations of target cannabinoids, and in particular cannabidiol (CBD). The methods may be deployed on-site in batch or continuous flow processes, and may further be utilized to derive other types of materials from plants, such as essential oils.

Methods for extracting and concentrating cannabinoids using ultrasound-enhanced solvent extraction. Freshly harvested cannabis plant materials, which may be selectively chosen plant parts or the entire plant itself, are shredded to a particular particle size. The plant material is then mixed with a solvent to form a slurry, and thereafter subjected to ultrasound to release intracellular contents into the solvent. Filtering steps are then applied to remove biomass, waxes and chlorophyll. Water removal and solvent recovery steps are further applied to ultimately derive an extract having high concentrations of target cannabinoids, and in particular cannabidiol (CBD). The methods may be deployed on-site in batch or continuous flow processes, and may further be utilized to derive other types of materials from plants, such as essential oils.

The present specification discloses methods of purifying one or more cannabinoids from a plant material using unique biphasic solvent systems and liquid-liquid chromatography as centrifugation partitioning chromatography (CPC) or counter current chromatography (CCC). The present specification also provides purified cannabinoids such as CBG, CBGA, CBGV, CBD, CBDA, CBDV, THC, THCA and THCV, compositions comprising one or more of these cannabinoids produced by the disclosed method, and methods for treating a disease or condition employing such purified cannabinoids and compositions.

Systems and methods of extracting compounds from botanical matter are provided. The system includes: a solvent source; an extraction vessel which receives botanical matter from which compounds, including at least one target compound are extracted into a solution; a detector that obtains real time information the compounds; a separation vessel for separating the target compound from the solution; a throttle located between the extraction vessel and the separation vessel for controlling flow of the solution; and a controller connected to the detector and the at the throttle for receiving and processing the real time information and controlling, via the throttle, flow rate of the solution from the extraction vessel to the separation vessel based at least partly on the processed real time information about the compounds.

Systems and methods of extracting compounds from botanical matter are provided. The system includes: a solvent source; an extraction vessel which receives botanical matter from which compounds, including at least one target compound are extracted into a solution; a detector that obtains real time information the compounds; a separation vessel for separating the target compound from the solution; a throttle located between the extraction vessel and the separation vessel for controlling flow of the solution; and a controller connected to the detector and the at the throttle for receiving and processing the real time information and controlling, via the throttle, flow rate of the solution from the extraction vessel to the separation vessel based at least partly on the processed real time information about the compounds.

The present invention relates to a method for extracting, separating and purifying compounds of interest obtained from essential oils and plant extracts which is continuously held.