Embodiments may provide systems and method for purifying natural and/or organically certified nutraceuticals, such as cannabinoids. Embodiments may include refined or unrefined solvents, refined or unrefined plant extracts, refined or unrefined source compounds to be purified to any degree. Embodiments may reduce the concentration of impurities such as other cannabinoids (e.g., THC), terpenes, pesticides, herbicides, mycotoxins, heavy metals, other solvents (e.g., ethanol), waxes, or other impurities. Embodiments may increase the concentration of target compound(s) from its respective source material.

Chromatography systems and methods for using carbon dioxide to separate one or more cannabis-derived compounds from other components of a mixture are generally described. Some of the methods described herein comprise transporting a mixture comprising a first cannabis-derived compound and one or more other components through a chromatography column containing a stationary phase comprising a packing material. In some embodiments, the mixture is transported through the column within a mobile phase that comprises carbon dioxide (e.g., supercritical CO.sub.2, liquid CO.sub.2). The mobile phase may be substantially free of a co-solvent that is in liquid phase at standard room temperature and pressure. In some embodiments, the mobile phase is free of any co-solvent and comprises 100 vol % carbon dioxide. The first cannabis-derived compound may interact with the stationary phase and/or the mobile phase to a different degree than the one or more other components of the mixture, causing at least partial separation of the first cannabis-derived compound from the one or more other components within the column. Due to this separation, at least one fraction of the mobile phase that comprises the first cannabis-derived compound and is substantially free of the one or more other components of the mixture may be collected.

The present invention relates to methods for treating cannabis biomass in order to isolate tetrahydrocannabinolic acid (THCA). In another aspect, the present invention relates to a process that involves purification followed by extraction of cannabis biomass to isolate and improve yields of high-purity crystalline extracts.

The present invention relates to methods for treating cannabis biomass in order to isolate tetrahydrocannabinolic acid (THCA). In another aspect, the present invention relates to a process that involves purification followed by extraction of cannabis biomass to isolate and improve yields of high-purity crystalline extracts.

The present invention relates to isomerizing hydroformylation of plant oils to feedstock chemicals and monomers. More particularly, the present invention relates to compound of formula (I) and process for preparation thereof using isomerizing functionalization of cashew nut shell liquid (CNSL). ##STR00001##

The present invention relates to a method for preparing cannabidiol by separation and purification using high-speed countercurrent chromatography, comprising: alcohol extraction and water precipitation, adsorption with a macroporous resin, and high-speed countercurrent chromatography separation. The present invention separates and obtains high-purity cannabidiol from industrial hemp flowers or leaves, while at the same time removing the psychotoxic component tetrahydrocannabinol by combining a macroporous resin chromatographic column with a high-speed countercurrent chromatograph, and optimizing process parameters, and the solvent used therein being environmentally friendly, leaving no residues, having low cost and being recyclable. Therefore, the method is suitable for industrial production.

The present invention relates to a method for preparing cannabidiol by separation and purification using high-speed countercurrent chromatography, comprising: alcohol extraction and water precipitation, adsorption with a macroporous resin, and high-speed countercurrent chromatography separation. The present invention separates and obtains high-purity cannabidiol from industrial hemp flowers or leaves, while at the same time removing the psychotoxic component tetrahydrocannabinol by combining a macroporous resin chromatographic column with a high-speed countercurrent chromatograph, and optimizing process parameters, and the solvent used therein being environmentally friendly, leaving no residues, having low cost and being recyclable. Therefore, the method is suitable for industrial production.

The separation of essential oils from a botanical biomass can be accomplished in a more effective way and with higher yields using microwaves to extract essential oils by dry or azeotropic distillation and isolating products from the essential oils.

The separation of essential oils from a botanical biomass can be accomplished in a more effective way and with higher yields using microwaves to extract essential oils by dry or azeotropic distillation and isolating products from the essential oils.

Methods of isolating phenols from phenol-containing media. The methods include combining a phospholipid-containing composition with the phenol-containing medium to generate a combined medium, incubating the combined medium to precipitate phenols in the combined medium and thereby form a phenol precipitate phase and a phenol-depleted phase, and separating the phenol precipitate phase and the phenol-depleted phase. The methods can further include extracting phenols from the separated phenol precipitate phase. The extracting can include mixing the separated phenol precipitate phase with an extraction solvent to solubilize in the extraction solvent at least a portion of the phenols originally present in the phenol precipitate phase.