The present invention relates to a new process for preparing 3-chloro-2-vinylphenylsulfonate derivatives.

The current application relates to cannabinoid derivatives of formula (I) and pharmaceutical compositions comprising the same. The cannabinoid derivative can be used for the treatment of diseases associated with cannabinoid receptor such as pain, ADHD/ADD, alcohol use disorder, anxiety disorder, and dementias.

The present disclosure provides phenolic compounds useful in the treatment of neurological conditions such as convulsions and tremors, having the structure of Formula (I):

##STR00001##

wherein R.sup.2, R.sup.4, & R.sup.5, are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating neurological conditions.

The present disclosure provides phenolic compounds useful in the treatment of neurological conditions such as convulsions and tremors, having the structure of Formula (I):

##STR00001##

wherein R.sup.2, R.sup.4, & R.sup.5, are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating neurological conditions.

The present disclosure provides phenolic compounds useful in the treatment of neurological conditions such as convulsions and tremors, having the structure of Formula (I): ##STR00001##
wherein R.sup.2, R.sup.4, & R.sup.5, are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating neurological conditions.

The present disclosure provides phenolic compounds useful in the treatment of neurological conditions such as convulsions and tremors, having the structure of Formula (I): ##STR00001##
wherein R.sup.2, R.sup.4, & R.sup.5, are as defined in the detailed description; pharmaceutical compositions comprising at least one of the compounds; and methods for treating neurological conditions.

Compositions include a curing agent of Formula 1:

##STR00001## R.sub.1 and R.sub.5 are independently H, Cl, Br, C.sub.1-18 alkyl or alkoxy which may contain chlorine or bromine substitutions, or X. R.sub.2-R.sub.4 are independently OH, H, Cl, Br, C.sub.1-18 alkyl or alkoxy which may contain chlorine or bromine substitutions, or X. At least one of R.sub.2, R.sub.3, and R.sub.4 is OH. Not more than 3 of R.sub.1-R.sub.5 are Cl or Br. X is Formula 2 or Formula 3:

##STR00002## R.sub.6-R.sub.10 are independently H, Cl, Br, C.sub.1-18 alkyl or alkoxy which may contain chlorine or bromine substitutions, acetyl or methylsulfonyl which may be alkyl- or aryl-substituted or may contain chlorine or bromine substitutions, nitro, nitrile, keto, aceto, or sulfone. R.sub.11-R.sub.18 are independently H, Cl, Br, C.sub.1-18 alkyl or alkoxy which may contain chlorine or bromine substitutions, nitro, or nitrile, where one of R.sub.11-R.sub.18 is a single bond to (Y).sub.n. Y is SO.sub.2 or O and n is 0 or 1. At least one of R.sub.1-R.sub.5, is Cl, Br, C.sub.1-18 alkyl or alkoxy which may contain chlorine or bromine substitutions, or X. When X is present, at least one of R.sub.6-R.sub.18 is Cl, Br, C.sub.1-18 alkyl or alkoxy which may contain chlorine or bromine substitutions, nitro, nitrile, keto, aceto, or sulfone.