Process for the preparation of a compound of Formula (I):

##STR00001## the process comprising the reaction of a compound of Formula (II) with malononitrile in the presence of a base and a palladium catalyst,

##STR00002## wherein X, Y and Z, independently of each other, represent fluoro, chloro or C.sub.1-4alkyl; and L is a leaving group; with the proviso that 1 or 2 of X and Y are, independently of each other, fluoro or chloro.

Process for the preparation of a compound of Formula (I), the process comprising the reaction of a compound of Formula (II) with malononitrile in the presence of a base and a palladium catalyst, Formula (II) wherein X, Y and Z, independently of each other, represent fluoro, chloro or C.sub.1-4alkyl; and L is a leaving group; with the proviso that 1 or 2 of X and Y are, independently of each other, fluoro or chloro. ##STR00001##

Process for the preparation of a compound of Formula (I), the process comprising the reaction of a compound of Formula (II) with malononitrile in the presence of a base and a palladium catalyst, Formula (II) wherein X, Y and Z, independently of each other, represent fluoro, chloro or C.sub.1-4alkyl; and L is a leaving group; with the proviso that 1 or 2 of X and Y are, independently of each other, fluoro or chloro. ##STR00001##

Process for the preparation of a compound of Formula (I), the process comprising the reaction of a compound of Formula (II) with malononitrile in the presence of a base and a palladium catalyst, Formula (II) wherein X, Y and Z, independently of each other, represent fluoro, chloro or C.sub.1-4alkyl; and L is a leaving group; with the proviso that 1 or 2 of X and Y are, independently of each other, fluoro or chloro. ##STR00001##

The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: ##STR00001##
which exhibits Acetyl-CoA carboxylase (ACC) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

The present disclosure provides solid forms, including a salt or co-crystal, of Compound I: ##STR00001##
which exhibits Acetyl-CoA carboxylase (ACC) inhibitory activity and may be useful in treating ACC mediated diseases. Also provided herein are processes or steps for the preparation of a Compound I and intermediates useful for the processes or steps described herein.

Provided are methods for removing a perfluorinated alkanoic acid from solutions containing the perfluorinated alkanoic acid and a fluorinated alkoxy acid. These methods include contacting the first solution with an anion-exchange resin to produce a second solution and a resultant anion-exchange resin having perfluorinated alkanoic acid adsorbed thereto, wherein the perfluorinated alkanoic acid is present in the first solution at a first concentration and is present in the second solution at a second concentration which is lower than the first concentration, and separating the second solution from the resultant anion-exchange resin.

Provided are methods for removing a perfluorinated alkanoic acid from solutions containing the perfluorinated alkanoic acid and a fluorinated alkoxy acid. These methods include contacting the first solution with an anion-exchange resin to produce a second solution and a resultant anion-exchange resin having perfluorinated alkanoic acid adsorbed thereto, wherein the perfluorinated alkanoic acid is present in the first solution at a first concentration and is present in the second solution at a second concentration which is lower than the first concentration, and separating the second solution from the resultant anion-exchange resin.

The present invention relates to the production of tri-functional aromatic molecules from diformylfuran, in particular to the production of tri-methyl benzene derivatives such as for example trimellitic acid or 1,2,4-tri(aminomethyl)benzene from diformylfuran and its derivatives.

The present invention relates to the production of tri-functional aromatic molecules from diformylfuran, in particular to the production of tri-methyl benzene derivatives such as for example trimellitic acid or 1,2,4-tri(aminomethyl)benzene from diformylfuran and its derivatives.